Discovery of potent hepatitis C virus NS5A inhibitors with dimeric structures

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 8, 2011, Pages 3795-3802

  Lemm, Julie A ^a   Leet, John E ^a   O'Boyle II, Donald R ^a   Romine, Jeffrey L ^a   Huang, Xiaohua Stella ^a   Schroeder, Daniel R ^a   Alberts, Jeffrey ^a,b   Cantone, Joseph L ^a   Sun, Jin Hua ^a   Nower, Peter T ^a   Martin, Scott W ^a   Serrano Wu, Michael H ^a,c   Meanwell, Nicholas A ^a   Snyder, Lawrence B ^a   Gao, Min ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BMS 790052; BMS 824; DIMER; HEPATITIS C VIRUS NS5A INHIBITOR; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; HEPATITIS C VIRUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REPLICON; VIRUS RESISTANCE;

ALANINE; ANTIVIRAL AGENTS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIARRHEA VIRUSES, BOVINE VIRAL; DRUG DISCOVERY; DRUG RESISTANCE, VIRAL; HEPACIVIRUS; HUMANS; IMIDAZOLES; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROLINE; STILBENES; THIAZOLIDINES; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 79960323218     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00146-11     Document Type: Article

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