Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ 9-THCV in animal models of Parkinson's disease

British Journal of Pharmacology

Volumn 163, Issue 7, 2011, Pages 1495-1506

  Garcia C ^a,b,c   Palomo Garo, C ^a,b,c   Garcia Arencibia M ^a,b   Ramos, J A ^a,b,c   Pertwee, R G ^d   Fernandez Ruiz J ^a,b,c  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c INSTITUTO RAMÓN Y CAJAL DE INVESTIGACIÓN SANITARIA IRYCIS   (Spain)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

9 THCV; 6 hydroxydopamine lesioned rats; cannabinoid receptors; LPS lesioned mice; neuroprotection; Parkinson's disease

Indexed keywords

CANNABIDIOL; CANNABINOID 2 RECEPTOR; CANNABINOID DERIVATIVE; DELTA 9 TETRAHYDROCANNABIVARIN; DOPAMINE; GLUTAMIC ACID; LIPOPOLYSACCHARIDE; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; CANNABINOID 1 RECEPTOR; DELTA TETRAHYDROCANNABIVARIN; NEUROPROTECTIVE AGENT; RIMONABANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL LOSS; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; LONG TERM CARE; MALE; MOTOR CONTROL; MOUSE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SINGLE DRUG DOSE; SUBSTANTIA NIGRA; SYMPTOMATOLOGY; TREATMENT DURATION; WILD TYPE; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; RECEPTOR BLOCKING;

ANIMALS; ANTIOXIDANTS; CANNABINOIDS; CYCLOHEXANOLS; DISEASE MODELS, ANIMAL; DOPAMINE; GLUTAMIC ACID; LIPOPOLYSACCHARIDES; MALE; MICE; MOTOR ACTIVITY; NEURONS; NEUROPROTECTIVE AGENTS; OXIDOPAMINE; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; SUBSTANTIA NIGRA; TETRAHYDROCANNABINOL; TYROSINE 3-MONOOXYGENASE;

EID: 79960300079     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01278.x     Document Type: Article

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