Prognostic value of radiobiological hypoxia during fractionated irradiation for local tumor control

Strahlentherapie und Onkologie

Volumn 187, Issue 5, 2011, Pages 306-310

  Zips, Daniel ^a   Böke, Simon ^a   Kroeber, Theresa ^a   Meinzer, Andreas ^a   Brüchner, Kerstin ^a   Thames, Howard D ^c   Baumann, Michael ^a,b   Yaromina, Ala ^a  

^a Helmholtz Zentrum Dresden Rossendorf   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Fractionated irradiation; Head and neck cancer; Human tumor xenograft; Local tumor control; Radiobiological hypoxia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CONTROL; CANCER STEM CELL; CELL HYPOXIA; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PROGNOSIS; RADIATION DOSE FRACTIONATION; RADIOBIOLOGY; RADIOSENSITIVITY; SQUAMOUS CELL CARCINOMA;

EID: 79960290731     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-011-2210-1     Document Type: Article

References (22)

1. Baumann M, Appold S, Zimmer J et al. Radiobiological hypoxia, oxygen tension, interstitial fluid pressure and relative viable tumour area in two human squamous cell carcinomas in nude mice during fractionated radiotherapy. Acta Oncol 2001;40:519-28. (Pubitemid 32682037)
2. Baumann M, Krause M, Hill R. Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer 2008;8:545-54. (Pubitemid 351881850)
3. Dellas K, Bache M, Pigorsch SU et al. Prognostic impact of HIF-1alpha expression in patients with definitive radiotherapy for cervical cancer. Strahlenther Onkol 2008;184:169-74. (Pubitemid 351365780)
4. Gerweck LE, Zaidi ST, Zietman A. Multivariate determinants of radiocurability. I: Prediction of single fraction tumor control doses. Int J Radiat Oncol Biol Phys 1994;29:57-66. (Pubitemid 24138865)
5. Horsman M, Wouters B, Joiner M et al. The oxygen effect and fractionated radiotherapy. In: Joiner M, Van der Kogel A (eds) Basic Clinical Radiobiology. 4th ed. London: Hodder Arnold, 2009;207-16.
6. Kappler M, Taubert H, Holzhausen HJ et al. Immunohistochemical detection of HIF-1alpha and CAIX in advanced head-and-neck cancer. Prognostic role and correlation with tumor markers and tumor oxygenation parameters. Strahlenther Onkol 2008;184:393-9.
7. Menegakis A, Yaromina A, Eicheler W et al. Prediction of clonogenic cell survival curves based on the number of residual DNA double strand breaks measured by gammaH2AX staining. Int J Radiat Biol 2009;85:1032-41.
8. Moulder JE, Rockwell S. Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data. Int J Radiat Oncol Biol Phys 1984;10:695-712. (Pubitemid 14084223)
9. O'Brien CA, Kreso A, Dick JE. Cancer stem cells in solid tumors: an overview. Semin Radiat Oncol 2009;19:71-7.
10. Olive PL, Banuelos CA, Durand RE et al. Endogenous and radiation-induced expression of gammaH2AX in biopsies from patients treated for carcinoma of the uterine cervix. Radiother Oncol;94:82-9.
11. Palcic B, Skarsgard LD. Reduced oxygen enhancement ratio at low doses of ionizing radiation. Radiat Res 1984;100:328-39. (Pubitemid 15223907)
12. Rades D, Setter C, Dunst J et al. Prognostic impact of VEGF and VEGF receptor 1 (FLT1) expression in patients irradiated for stage II/III non-small cell lung cancer (NSCLC). Strahlenther Onkol 2010;186:307-14.
13. Rofstad EK. Hypoxia and reoxygenation in human melanoma xenografts. Int J Radiat Oncol Biol Phys 1989;17:81-9. (Pubitemid 19173242)
14. Rohrer Bley C, Laluhova D, Roos M et al. Correlation of pretreatment polaro graphically measured oxygen pressures with quantified contrast-enhanced power doppler ultrasonography in spontaneous canine tumors and their impact on outcome after radiation therapy. Strahlenther Onkol 2009;185:756-62.
15. Vaupel P. Tumor microenvironmental physiology and its implications for radiation oncology. Semin Radiat Oncol 2004;14:198-206. (Pubitemid 38903223)
16. Walker AM, Suit HD. Assessment of local tumor control using censored tumor response data. Int J Radiat Oncol Biol Phys 1983;9:383-6. (Pubitemid 13055184)
17. Wouters B, Koritzinsky M. The tumour microenvironment and cellular hypoxia responses. In: Joiner M, Van der Kogel A (eds) Basic Clincal Radiobiology. 4th ed. London: Hodder Arnold 2009;217-32.
18. Yaromina A, Krause M, Thames HD et al. Pre-treatment number of clonogenic tumour cells and their radiosensitivity are major determinants of local tumour control after fractionated irradiation. Radiother Oncol 2007;83:304-10. (Pubitemid 46915546)
19. Yaromina A, Kroeber T, Meinzer A et al. Exploratory study of the prognostic value of microenvironmental parameters during fractionated irradiation in human squamous cell carcinoma xenografts. Int J Radiat Oncol Biol Phys 2011; in press.
20. Yaromina A, Thames H, Zhou X, et al. Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation. Radiother Oncol 2010;96:116-22.
21. Yaromina A, Zips D, Thames HD et al. Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) cell lines in nude mice: the need for a multivariate approach in biomarker studies. Radiother Oncol 2006;81:122-9. (Pubitemid 44780780)
22. Zips D. Tumour growth and response to radiation. In: Joiner M, van der Kogel A (eds) Basic clinical radiobiology. 4th ed. London: Hodder Arnold 2009;78-101.