High-resolution genomic profiling in hairy cell leukemia-variant compared with typical hairy cell leukemia

Leukemia

Volumn 25, Issue 7, 2011, Pages 1189-1192

  Hockley, S L ^a   Morgan, G J ^a   Leone, P E ^a   Walker, B A ^a   Morilla, A ^a   Else, M ^a   Wotherspoon, A ^b   Dearden, C ^a   Catovsky, D ^a   Gonzalez, D ^a   Matutes, E ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PROTEIN P53;

ADULT; AGED; ALLELIC IMBALANCE; ARTICLE; CHROMOSOME 17P; CHROMOSOME 5; CHROMOSOME 7Q; CHROMOSOME ABERRATION; CHROMOSOME DELETION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA COPY NUMBER ABERRATION; FEMALE; GENE DOSAGE; GENETIC GAIN; GENETIC VARIABILITY; GENOMICS; HAIRY CELL LEUKEMIA; HAIRY CELL LEUKEMIA VARIANT; HETEROZYGOSITY LOSS; HUMAN; IMMUNOGLOBULIN HEAVY CHAIN GENE; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC HYPERMUTATION; TRISOMY;

EID: 79960285663     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.47     Document Type: Article

References (8)

1. Foucar K, Falini B, Catovsky D, Stein H. Hairy cell leukaemia. In: Swerdlow SH, Campo E, Harris NL et al (eds). WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press: Lyon, 2008.
2. Matutes E, Wotherspoon A, Catovsky D. The variant form of hairycell leukaemia. Best Pract Res Clin Haematol 2003; 16: 41-56.
3. Hockley SL, Giannouli S, Morilla A, Wotherspoon A, Morgan GJ, Matutes E et al. Insight into the molecular pathogenesis of hairy cell leukaemia, hairy cell leukaemia variant and splenic marginal zone lymphoma, provided by the analysis of their IGH rearrangements and somatic hypermutation patterns. Br J Haematol 2009; 148: 666-669.
4. Sambani C, Trafalis DT, Mitsoulis-Mentzikoff C, Poulakidas E, Makropoulos V, Pantelias GE et al. Clonal chromosome rearrangements in hairy cell leukemia: personal experience and review of literature. Cancer Genet Cytogenet 2001; 129: 138-144. (Pubitemid 32826306)
5. Andersen CL, Gruszka-Westwood A, Ostergaard M, Koch J, Jacobsen E, Kjeldsen E et al. A narrow deletion of 7q is common to HCL, and SMZL, but not CLL. Eur J Haematol 2004; 72: 390-402. (Pubitemid 38703530)
6. Konig EA, KusserWC, Day C, Porzsolt F, Glickman BW, Messer G et al. p53 mutations in hairy cell leukemia. Leukemia 2000; 14: 706-711. (Pubitemid 30195463)
7. Dierlamm J, Stefanova M, Wlodarska I, Michaux L, Hinz K, Penas EM et al. Chromosomal gains and losses are uncommon in hairy cell leukemia: a study based on comparative genomic hybridization and interphase fluorescence in situ hybridization. Cancer Genet Cytogenet 2001; 128: 164-167. (Pubitemid 32706592)
8. Forconi F, Sozzi E, Cencini E, Zaja F, Intermesoli T, Stelitano C et al. Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single agent cladribine and with more aggressive behavior. Blood 2009; 114: 4696-4702.