메뉴 건너뛰기




Volumn 41, Issue 2, 2011, Pages 387-399

SILAC-based proteomic analysis to dissect the "histone modification signature" of human breast cancer cells

Author keywords

Breast cancer; Epigenetic mark; Histones; Mass spectrometry; Quantitative proteomics

Indexed keywords

HISTONE H3; HISTONE H4;

EID: 79960281535     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-010-0668-2     Document Type: Article
Times cited : (65)

References (43)
  • 1
    • 75649094197 scopus 로고    scopus 로고
    • Mass spectrometry in epigenetic research
    • 19957154 10.1007/978-1-60327-194-3-13 1:CAS:528:DC%2BC3cXnvFWntr8%3D
    • HC Beck 2010 Mass spectrometry in epigenetic research Methods Mol Biol 593 263 282 19957154 10.1007/978-1-60327-194-3-13 1:CAS:528:DC%2BC3cXnvFWntr8%3D
    • (2010) Methods Mol Biol , vol.593 , pp. 263-282
    • Beck, H.C.1
  • 2
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • DOI 10.1093/emboj/cdg542
    • AP Bracken D Pasini M Capra E Prosperini E Colli K Helin 2003 EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer EMBO J 22 20 5323 5335 14532106 10.1093/emboj/cdg542 1:CAS:528: DC%2BD3sXot1Cqsro%3D (Pubitemid 37279943)
    • (2003) EMBO Journal , vol.22 , Issue.20 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 3
    • 23944472674 scopus 로고    scopus 로고
    • Mass spectrometric analysis of histone posttranslational modifications
    • DOI 10.1016/j.ymeth.2005.03.009, PII S1046202305000782, Protein Acetylation
    • AL Burlingame X Zhang RJ Chalkley 2005 Mass spectrometric analysis of histone posttranslational modifications Methods 36 4 383 394 16112065 10.1016/j.ymeth.2005.03.009 1:CAS:528:DC%2BD2MXos1ahs7k%3D (Pubitemid 41188070)
    • (2005) Methods , vol.36 , Issue.4 , pp. 383-394
    • Burlingame, A.L.1    Zhang, X.2    Chalkley, R.J.3
  • 4
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: Patterns and paradigms
    • 19308066 10.1038/nrg2540 1:CAS:528:DC%2BD1MXksF2rsL0%3D
    • H Cedar Y Bergman 2009 Linking DNA methylation and histone modification: patterns and paradigms Nat Rev Genet 10 5 295 304 19308066 10.1038/nrg2540 1:CAS:528:DC%2BD1MXksF2rsL0%3D
    • (2009) Nat Rev Genet , vol.10 , Issue.5 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 5
    • 34548312353 scopus 로고    scopus 로고
    • Histone proteomics and the epigenetic regulation of nucleosome mobility
    • DOI 10.1586/14789450.4.4.465
    • MS Cosgrove 2007 Histone proteomics and the epigenetic regulation of nucleosome mobility Exp Rev Proteomics 4 4 465 478 10.1586/14789450.4.4.465 1:CAS:528:DC%2BD2sXptFyrtbo%3D (Pubitemid 47347595)
    • (2007) Expert Review of Proteomics , vol.4 , Issue.4 , pp. 465-478
    • Cosgrove, M.S.1
  • 6
    • 57449099865 scopus 로고    scopus 로고
    • MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
    • 19029910 10.1038/nbt.1511 1:CAS:528:DC%2BD1cXhsVWjtLzJ
    • J Cox M Mann 2008 MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification Nat Biotechnol 26 12 1367 1372 19029910 10.1038/nbt.1511 1:CAS:528:DC%2BD1cXhsVWjtLzJ
    • (2008) Nat Biotechnol , vol.26 , Issue.12 , pp. 1367-1372
    • Cox, J.1    Mann, M.2
  • 7
    • 0034968451 scopus 로고    scopus 로고
    • Emerging connections between DNA methylation and histone acetylation
    • JR Dobosy EU Selker 2001 Emerging connections between DNA methylation and histone acetylation Cell Mol Life Sci 58 5-6 721 727 11437233 10.1007/PL00000895 1:CAS:528:DC%2BD3MXlt1ait7o%3D (Pubitemid 32553029)
    • (2001) Cellular and Molecular Life Sciences , vol.58 , Issue.5-6 , pp. 721-727
    • Dobosy, J.R.1    Selker, E.U.2
  • 9
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
    • DOI 10.1038/sj.onc.1205600
    • M Esteller 2002 CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future Oncogene 21 35 5427 5440 12154405 10.1038/sj.onc.1205600 1:CAS:528:DC%2BD38XlslSqt7w%3D (Pubitemid 34983479)
    • (2002) Oncogene , vol.21 , Issue.35 REV. ISS. 3 , pp. 5427-5440
    • Esteller, M.1
  • 10
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • DOI 10.1038/301089a0
    • AP Feinberg B Vogelstein 1983 Hypomethylation distinguishes genes of some human cancers from their normal counterparts Nature 301 5895 89 92 6185846 10.1038/301089a0 1:CAS:528:DyaL3sXms1ertA%3D%3D (Pubitemid 13154475)
    • (1983) Nature , vol.301 , Issue.5895 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 11
    • 33947153008 scopus 로고    scopus 로고
    • Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer
    • DOI 10.1002/ijc.22474
    • W Feng Z Lu RZ Luo X Zhang E Seto WS Liao Y Yu 2007 Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer Int J Cancer 120 8 1664 1668 17230502 10.1002/ijc.22474 1:CAS:528:DC%2BD2sXjtFOktro%3D (Pubitemid 46399351)
    • (2007) International Journal of Cancer , vol.120 , Issue.8 , pp. 1664-1668
    • Feng, W.1    Lu, Z.2    Luo, R.Z.3    Zhang, X.4    Seto, E.5    Liao, W.S.-L.6    Yu, Y.7
  • 13
    • 7544229161 scopus 로고    scopus 로고
    • Application of mass spectrometry to the identification and quantification of histone post-translational modifications
    • DOI 10.1002/jcb.20106
    • MA Freitas AR Sklenar MR Parthun 2004 Application of mass spectrometry to the identification and quantification of histone post-translational modifications J Cell Biochem 92 4 691 700 15211567 10.1002/jcb.20106 1:CAS:528:DC%2BD2cXlslenur0%3D (Pubitemid 44264260)
    • (2004) Journal of Cellular Biochemistry , vol.92 , Issue.4 , pp. 691-700
    • Freitas, M.A.1    Sklenar, A.R.2    Parthun, M.R.3
  • 14
    • 33846809241 scopus 로고    scopus 로고
    • Characterization of histones and their post-translational modifications by mass spectrometry
    • DOI 10.1016/j.cbpa.2006.11.022, PII S1367593106001864
    • BA Garcia J Shabanowitz DF Hunt 2007 Characterization of histones and their post-translational modifications by mass spectrometry Curr Opin Chem Biol 11 1 66 73 17157550 10.1016/j.cbpa.2006.11.022 1:CAS:528:DC%2BD2sXhsFOhsL8%3D (Pubitemid 46216127)
    • (2007) Current Opinion in Chemical Biology , vol.11 , Issue.1 , pp. 66-73
    • Garcia, B.A.1    Shabanowitz, J.2    Hunt, D.F.3
  • 15
    • 0345357773 scopus 로고    scopus 로고
    • Gene Silencing in Cancer in Association with Promoter Hypermethylation
    • DOI 10.1056/NEJMra023075
    • JG Herman SB Baylin 2003 Gene silencing in cancer in association with promoter hypermethylation N Engl J Med 349 21 2042 2054 14627790 10.1056/NEJMra023075 1:CAS:528:DC%2BD3sXptFKmu7s%3D (Pubitemid 37448928)
    • (2003) New England Journal of Medicine , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 16
    • 33845781998 scopus 로고    scopus 로고
    • Genome-wide and locus-specific DNA hypomethylation in G9a deficient mouse embryonic stem cells
    • DOI 10.1111/j.1365-2443.2006.01029.x
    • K Ikegami M Iwatani M Suzuki M Tachibana Y Shinkai S Tanaka JM Greally S Yagi N Hattori K Shiota 2007 Genome-wide and locus-specific DNA hypomethylation in G9a deficient mouse embryonic stem cells Genes Cells 12 1 1 11 17212651 10.1111/j.1365-2443.2006.01029.x 1:CAS:528:DC%2BD2sXpt1Kqtw%3D%3D (Pubitemid 44971094)
    • (2007) Genes to Cells , vol.12 , Issue.1 , pp. 1-11
    • Ikegami, K.1    Iwatani, M.2    Suzuki, M.3    Tachibana, M.4    Shinkai, Y.5    Tanaka, S.6    Greally, J.M.7    Yagi, S.8    Hattori, N.9    Shiota, K.10
  • 17
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • DOI 10.1126/science.1063127
    • T Jenuwein CD Allis 2001 Translating the histone code Science 293 5532 1074 1080 11498575 10.1126/science.1063127 1:CAS:528:DC%2BD3MXmtVWltro%3D (Pubitemid 32758077)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 18
    • 77951855269 scopus 로고    scopus 로고
    • Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36
    • 20150217 10.1074/mcp.M900489-MCP200 1:CAS:528:DC%2BC3cXpslyrsLo%3D
    • HR Jung D Pasini K Helin ON Jensen 2010 Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36 Mol Cell Proteomics 9 5 838 850 20150217 10.1074/mcp.M900489-MCP200 1:CAS:528: DC%2BC3cXpslyrsLo%3D
    • (2010) Mol Cell Proteomics , vol.9 , Issue.5 , pp. 838-850
    • Jung, H.R.1    Pasini, D.2    Helin, K.3    Jensen, O.N.4
  • 19
    • 38649083118 scopus 로고    scopus 로고
    • Assigning significance to peptides identified by tandem mass spectrometry using decoy databases
    • DOI 10.1021/pr700600n
    • L Kall JD Storey MJ MacCoss WS Noble 2008 Assigning significance to peptides identified by tandem mass spectrometry using decoy databases J Proteome Res 7 1 29 34 18067246 10.1021/pr700600n (Pubitemid 351171110)
    • (2008) Journal of Proteome Research , vol.7 , Issue.1 , pp. 29-34
    • Kall, L.1    Storey, J.D.2    MacCoss, M.J.3    Noble, W.S.4
  • 20
    • 0033214591 scopus 로고    scopus 로고
    • Localization of labile posttranslational modifications by electron capture dissociation: The case of γ-carboxyglutamic acid
    • DOI 10.1021/ac990684x
    • NL Kelleher RA Zubarev K Bush B Furie BC Furie FW McLafferty CT Walsh 1999 Localization of labile posttranslational modifications by electron capture dissociation: the case of gamma-carboxyglutamic acid Anal Chem 71 19 4250 4253 10517147 10.1021/ac990684x 1:CAS:528:DyaK1MXlt12ksLs%3D (Pubitemid 29466405)
    • (1999) Analytical Chemistry , vol.71 , Issue.19 , pp. 4250-4253
    • Kelleher, N.L.1    Zubarev, R.A.2    Bush, K.3    Furie, B.4    Furie, B.C.5    McLafferty, F.W.6    Walsh, C.T.7
  • 21
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin Modifications and Their Function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • T Kouzarides 2007 Chromatin modifications and their function Cell 128 4 693 705 17320507 10.1016/j.cell.2007.02.005 1:CAS:528:DC%2BD2sXis12ju7Y%3D (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 23
    • 33749657892 scopus 로고    scopus 로고
    • PTMs on H3 Variants before Chromatin Assembly Potentiate Their Final Epigenetic State
    • DOI 10.1016/j.molcel.2006.08.019, PII S1097276506006009
    • A Loyola T Bonaldi D Roche A Imhof G Almouzni 2006 PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state Mol Cell 24 2 309 316 17052464 10.1016/j.molcel.2006.08.019 1:CAS:528:DC%2BD28XhtF2rs7zN (Pubitemid 44557123)
    • (2006) Molecular Cell , vol.24 , Issue.2 , pp. 309-316
    • Loyola, A.1    Bonaldi, T.2    Roche, D.3    Imhof, A.4    Almouzni, G.5
  • 24
    • 33845329203 scopus 로고    scopus 로고
    • Functional and quantitative proteomics using SILAC
    • DOI 10.1038/nrm2067, PII NRM2067
    • M Mann 2006 Functional and quantitative proteomics using SILAC Nat Rev Mol Cell Biol 7 12 952 958 17139335 10.1038/nrm2067 1:CAS:528:DC%2BD28Xht1KisrrF (Pubitemid 44871421)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.12 , pp. 952-958
    • Mann, M.1
  • 25
    • 5644231221 scopus 로고    scopus 로고
    • Characterization of Tetrahymena histone H2B variants and posttranslational populations by Electron Capture Dissociation (ECD) Fourier Transform Ion Cyclotron Mass Spectrometry (FT-ICR MS)
    • DOI 10.1074/mcp.M400041-MCP200
    • KF Medzihradszky X Zhang RJ Chalkley S Guan MA McFarland MJ Chalmers AG Marshall RL Diaz CD Allis AL Burlingame 2004 Characterization of Tetrahymena histone H2B variants and posttranslational populations by electron capture dissociation (ECD) Fourier transform ion cyclotron mass spectrometry (FT-ICR MS) Mol Cell Proteomics 3 9 872 886 15199121 10.1074/mcp.M400041-MCP200 1:CAS:528:DC%2BD2cXotlGmu74%3D (Pubitemid 39369200)
    • (2004) Molecular and Cellular Proteomics , vol.3 , Issue.9 , pp. 872-886
    • Medzihradszky, K.F.1    Zhang, X.2    Chalkley, R.J.3    Guan, S.4    McFarland, M.A.5    Chalmers, M.J.6    Marshall, A.G.7    Diaz, R.L.8    Allis, C.D.9    Burlingame, A.L.10
  • 27
    • 18744375196 scopus 로고    scopus 로고
    • Identifying and quantifying in vivo methylation sites by heavy methyl SILAC
    • 15782174 10.1038/nmeth715 1:CAS:528:DC%2BD2MXisVGhurc%3D
    • SE Ong G Mittler M Mann 2004 Identifying and quantifying in vivo methylation sites by heavy methyl SILAC Nat Methods 1 2 119 126 15782174 10.1038/nmeth715 1:CAS:528:DC%2BD2MXisVGhurc%3D
    • (2004) Nat Methods , vol.1 , Issue.2 , pp. 119-126
    • Ong, S.E.1    Mittler, G.2    Mann, M.3
  • 28
    • 1642272372 scopus 로고    scopus 로고
    • Shotgun Annotation of Histone Modifications: A New Approach for Streamlined Characterization of Proteins by Top Down Mass Spectrometry
    • DOI 10.1021/ja039748i
    • JJ Pesavento YB Kim GK Taylor NL Kelleher 2004 Shotgun annotation of histone modifications: a new approach for streamlined characterization of proteins by top down mass spectrometry J Am Chem Soc 126 11 3386 3387 15025441 10.1021/ja039748i 1:CAS:528:DC%2BD2cXhs1ylsro%3D (Pubitemid 38366706)
    • (2004) Journal of the American Chemical Society , vol.126 , Issue.11 , pp. 3386-3387
    • Pesavento, J.J.1    Kim, Y.-B.2    Taylor, G.K.3    Kelleher, N.L.4
  • 29
    • 39649119288 scopus 로고    scopus 로고
    • The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma
    • DOI 10.1002/ijc.23283
    • S Pfister S Rea M Taipale F Mendrzyk B Straub C Ittrich O Thuerigen HP Sinn A Akhtar P Lichter 2008 The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma Int J Cancer 122 6 1207 1213 18058815 10.1002/ijc.23283 1:CAS:528:DC%2BD1cXit1yhsrk%3D (Pubitemid 351287218)
    • (2008) International Journal of Cancer , vol.122 , Issue.6 , pp. 1207-1213
    • Pfister, S.1    Rea, S.2    Taipale, M.3    Mendrzyk, F.4    Straub, B.5    Ittrich, C.6    Thuerigen, O.7    Sinn, H.P.8    Akhtar, A.9    Lichter, P.10
  • 31
    • 34548183872 scopus 로고    scopus 로고
    • Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
    • DOI 10.1038/nprot.2007.261, PII NPROT.2007.261
    • J Rappsilber M Mann Y Ishihama 2007 Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips Nat Protoc 2 8 1896 1906 17703201 10.1038/nprot.2007.261 1:CAS:528:DC%2BD2sXhtFagtr3O (Pubitemid 47308128)
    • (2007) Nature Protocols , vol.2 , Issue.8 , pp. 1896-1906
    • Rappsilber, J.1    Mann, M.2    Ishihama, Y.3
  • 32
    • 24944544077 scopus 로고    scopus 로고
    • Precise and parallel characterization of coding polymorphisms, alternative splicing, and modifications in human proteins by mass spectrometry
    • DOI 10.1074/mcp.M500064-MCP200
    • MJ Roth AJ Forbes MT Boyne II YB Kim DE Robinson NL Kelleher 2005 Precise and parallel characterization of coding polymorphisms, alternative splicing, and modifications in human proteins by mass spectrometry Mol Cell Proteomics 4 7 1002 1008 15863400 10.1074/mcp.M500064-MCP200 1:CAS:528:DC%2BD2MXmtFKkurk%3D (Pubitemid 41309157)
    • (2005) Molecular and Cellular Proteomics , vol.4 , Issue.7 , pp. 1002-1008
    • Roth, M.J.1    Forbes, A.J.2    Boyne II, M.T.3    Kim, Y.-B.4    Robinson, D.E.5    Kelleher, N.L.6
  • 33
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • DOI 10.1038/nature03672
    • DB Seligson S Horvath T Shi H Yu S Tze M Grunstein SK Kurdistani 2005 Global histone modification patterns predict risk of prostate cancer recurrence Nature 435 7046 1262 1266 15988529 10.1038/nature03672 1:CAS:528: DC%2BD2MXls1Ontbg%3D (Pubitemid 40943093)
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 34
    • 32344453537 scopus 로고    scopus 로고
    • Gene-specific characterization of human histone H2B by electron capture dissociation
    • DOI 10.1021/pr050268v
    • N Siuti MJ Roth CA Mizzen NL Kelleher JJ Pesavento 2006 Gene-specific characterization of human histone H2B by electron capture dissociation J Proteome Res 5 2 233 239 16457587 10.1021/pr050268v 1:CAS:528: DC%2BD28XitFSksQ%3D%3D (Pubitemid 43222290)
    • (2006) Journal of Proteome Research , vol.5 , Issue.2 , pp. 233-239
    • Siuti, N.1    Roth, M.J.2    Mizzen, C.A.3    Kelleher, N.L.4    Pesavento, J.J.5
  • 35
    • 34247110340 scopus 로고    scopus 로고
    • Mass spectrometry-based strategies for characterization of histones and their post-translational modifications
    • DOI 10.1586/14789450.4.2.211
    • X Su C Ren MA Freitas 2007 Mass spectrometry-based strategies for characterization of histones and their post-translational modifications Exp Rev Proteomics 4 2 211 225 10.1586/14789450.4.2.211 1:CAS:528:DC%2BD2sXkt1Wru74%3D (Pubitemid 46588457)
    • (2007) Expert Review of Proteomics , vol.4 , Issue.2 , pp. 211-225
    • Su, X.1    Ren, C.2    Freitas, M.A.3
  • 36
    • 65649096557 scopus 로고    scopus 로고
    • Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression
    • 19383825 10.1158/1078-0432.CCR-08-2319 1:CAS:528:DC%2BD1MXltFOrur4%3D
    • J Suzuki YY Chen GK Scott S Devries K Chin CC Benz FM Waldman ES Hwang 2009 Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression Clin Cancer Res 15 9 3163 3171 19383825 10.1158/1078-0432.CCR-08-2319 1:CAS:528:DC%2BD1MXltFOrur4%3D
    • (2009) Clin Cancer Res , vol.15 , Issue.9 , pp. 3163-3171
    • Suzuki, J.1    Chen, Y.Y.2    Scott, G.K.3    Devries, S.4    Chin, K.5    Benz, C.C.6    Waldman, F.M.7    Hwang, E.S.8
  • 37
    • 0035816682 scopus 로고    scopus 로고
    • Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3
    • 11316813 10.1074/jbc.M101914200 1:CAS:528:DC%2BD3MXlt1ans7s%3D
    • M Tachibana K Sugimoto T Fukushima Y Shinkai 2001 Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3 J Biol Chem 276 27 25309 25317 11316813 10.1074/jbc.M101914200 1:CAS:528:DC%2BD3MXlt1ans7s%3D
    • (2001) J Biol Chem , vol.276 , Issue.27 , pp. 25309-25317
    • Tachibana, M.1    Sugimoto, K.2    Fukushima, T.3    Shinkai, Y.4
  • 39
    • 32344453899 scopus 로고    scopus 로고
    • Mass spectrometric characterization of human histone H3: A bird's eye view
    • DOI 10.1021/pr050266a
    • CE Thomas NL Kelleher CA Mizzen 2006 Mass spectrometric characterization of human histone H3: a bird's eye view J Proteome Res 5 2 240 247 16457588 10.1021/pr050266a 1:CAS:528:DC%2BD28XisFCnsg%3D%3D (Pubitemid 43222291)
    • (2006) Journal of Proteome Research , vol.5 , Issue.2 , pp. 240-247
    • Thomas, C.E.1    Kelleher, N.L.2    Mizzen, C.A.3
  • 41
    • 32544452237 scopus 로고    scopus 로고
    • Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins
    • VP Tryndyak O Kovalchuk IP Pogribny 2006 Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins Cancer Biol Ther 5 1 65 70 16322686 10.4161/cbt.5.1.2288 1:CAS:528:DC%2BD28XkvVSnt78%3D (Pubitemid 43234980)
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.1 , pp. 65-70
    • Tryndyak, V.P.1    Kovalchuk, O.2    Pogribny, I.P.3
  • 43
    • 0036652176 scopus 로고    scopus 로고
    • Histone acetylation and deacetylation: Identification of acetylation and methylation sites of HeLa histone H4 by mass spectrometry
    • 12239278 10.1074/mcp.M200031-MCP200 1:CAS:528:DC%2BD38XnsFKls7w%3D
    • K Zhang KE Williams L Huang P Yau JS Siino EM Bradbury PR Jones MJ Minch AL Burlingame 2002 Histone acetylation and deacetylation: identification of acetylation and methylation sites of HeLa histone H4 by mass spectrometry Mol Cell Proteomics 1 7 500 508 12239278 10.1074/mcp.M200031-MCP200 1:CAS:528:DC%2BD38XnsFKls7w%3D
    • (2002) Mol Cell Proteomics , vol.1 , Issue.7 , pp. 500-508
    • Zhang, K.1    Williams, K.E.2    Huang, L.3    Yau, P.4    Siino, J.S.5    Bradbury, E.M.6    Jones, P.R.7    Minch, M.J.8    Burlingame, A.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.