Chemical synthesis of the (25R)- and (25S)-epimers of 3α,7α, 12α-trihydroxy-5α-cholestan-27-oic acid as well as their corresponding glycine and taurine conjugates

Chemistry and Physics of Lipids

Volumn 164, Issue 5, 2011, Pages 368-377

  Ogawa, Shoujiro ^a   Mitamura, Kuniko ^b   Ikegawa, Shigeo ^b   Krasowski, Matthew D ^c   Hagey, Lee R ^d   Hofmann, Alan F ^d   Iida, Takashi ^a  

^a NIHON UNIVERSITY   (Japan)

^b KINKI UNIVERSITY   (Japan)

^c UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

3 ,7 ,12 Trihydroxy 5 cholestan 27 oic acid; 5 Bile acid; Allo bile acid; Bile acid biosynthesis; Chemical synthesis; NMR

Indexed keywords

3ALPHA,7ALPHA,12ALPHA TRIHYDROXY 5ALPHA CHOLESTAN 27 OIC ACID; BILE ACID; BILE ACID CONJUGATE; CHOLIC ACID; DICARBOXYLIC ACID; ESTER; GLYCINE; IODINE DERIVATIVE; METHYLMALONIC ACID; TAURINE; TRIPHENYLPHOSPHINE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DECARBOXYLATION; EPIMER; HYDROLYSIS; IODINATION; NONHUMAN; NUCLEOPHILICITY; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SYNTHESIS;

EID: 79960266039     PISSN: 00093084     EISSN: 18732941     Source Type: Journal    
DOI: 10.1016/j.chemphyslip.2011.04.008     Document Type: Article

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