Increased MLL gene rearrangements in amniocytes from fetuses of mothers who smoke

Leukemia Research

Volumn 35, Issue 8, 2011, Pages 1066-1069

  de la Chica, Rosa Ana ^a   Mediano, Carmen ^b   Salido, Marta ^a   Espinet, Blanca ^a   Manresa, Josep Maria ^c   Solé, Francesc ^a  

^a HOSPITAL DEL MAR   (Spain)

^b Infantil Vall d'Hebron   (Spain)

^c INSTITUT CATALÀ DE LA SALUT   (Spain)

Author keywords

Amniocytes; Maternal smoking; MLL rearrangements; Tobacco

Indexed keywords

ADULT; AMNION CELL; ARTICLE; CANCER RISK; CELL CULTURE; CHROMOSOME 11Q; CIGARETTE SMOKING; CONTROLLED STUDY; FEMALE; FETUS; GENE; GENE REARRANGEMENT; GENOTOXICITY; HUMAN; HUMAN CELL; LEUKEMIA; MATERNAL SMOKING; MLL GENE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ADULT; AMNIOTIC FLUID; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 11; FEMALE; FETUS; GENE REARRANGEMENT; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MOTHERS; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PREGNANCY; PROGNOSIS; PROSPECTIVE STUDIES; SMOKING;

EID: 79960238529     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.04.010     Document Type: Article

References (12)

1. Chang J.S. Parental smoking and childhood leukemia. Methods Mol Biol 2009, 472:103-137.
2. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al. editors: WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues. IARC: Lyon 2008.
3. Ford A.M., Ridge S.A., Cabrera M.E., Mahmoud H., Steel C.M., Chan L.C., et al. In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 1993, 363:358-360.
4. Gale K.B., Ford A.M., Repp R., Borkhardt A., Keller C., Eden O.B., et al. Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. Proc Natl Acad Sci USA 1997, 94:13950-13954.
5. de la Chica R.A., Ribas I., Giraldo J., Egozcue J., Fuster C. Chromosomal instability in amniocytes from fetuses of mothers who smoke. JAMA 2005, 10:1212-1222.
6. Liang K.Y., Zeger S.L. Longitudinal data analysis using generalized linear models. Biometrika 1986, 73:13-22.
7. Villalbí J.R., Rodríguez-Sanz M., Villegas R., Borrell C. Changes in the population smoking patterns: Barcelona, 1983-2006. Med Clin (Barc) 2009, 28(132):414-419.
8. Jauniaux E., Gulbis B., Acharya G., Thiry P., Rodeck C. Maternal tobacco exposure and cotinine levels in fetal fluids in the first half of pregnancy. Obstet Gynecol 1999, 93:25-29.
9. Spitz M.R., Wei Q., Dong Q., Amos C.I., Wu X. Genetic susceptibility to lung cancer: the role of DNA damage and repair. Cancer Epidemiol Biomarkers Prev 2003, 12:689-698.
10. Richards R.I. Fragile and unstable chromosomes in cancer: causes and consequences. Trends Genet 2001, 17:339-345.
11. Mahgoub N., Parker R.I., Hosler M.R., Close P., Winick N.J., Masterson M., et al. RAS mutations in pediatric leukemias with MLL gene rearrangements. Genes Chromosomes Cancer 1998, 21:270-275.
12. Zangrando A., Dell'orto M.C., Te Kronnie G., Basso G. MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures. BMC Med Genomics 2009, 23:2-36.