Endometrial regeneration using autologous adult stem cells followed by conception by in vitro fertilization in a patient of severe Ashermans syndrome

Journal of Human Reproductive Sciences

Volumn 4, Issue 1, 2011, Pages 43-48

  Nagori, Chaitanya ^a   Panchal, Sonal ^a   Patel, Himanshu ^b  

^a Dr Nagoris Institute for Infertility   (India)

^b Stem Cure (Centre for Reproductive Medicine and Stem Cell Therapy)   (India)

Author keywords

Adult stem cells; Ashermans syndrome; endometrial regeneration; endometrial thickness; hormone replacement therapy

Indexed keywords

ACETYLSALICYLIC ACID; CD133 ANTIGEN; CD9 ANTIGEN; CHORIONIC GONADOTROPIN BETA SUBUNIT; COPPER INTRAUTERINE DEVICE; ESTRADIOL VALERATE; ESTROGEN; ETHINYLESTRADIOL; HEPARIN; HERMES ANTIGEN; MEDROXYPROGESTERONE ACETATE; PROGESTERONE; THY 1 ANTIGEN;

ADULT; ADULT STEM CELL; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BONE MARROW; BONE MARROW BIOPSY; CASE REPORT; CELL DIFFERENTIATION; CELL ISOLATION; CELL SEPARATION; COLOR ULTRASOUND FLOWMETRY; CONCEPTION; CURETTAGE; DISEASE SEVERITY; DOPPLER ECHOGRAPHY; DRUG DOSE INCREASE; ECHOCARDIOGRAPHY; ECHOGRAPHY; EMBRYO TRANSFER; ENDOMETRIAL ANGIOGENIC STEM CELL; ENDOMETRIUM; ENDOMETRIUM REGENERATION; ESTROGEN THERAPY; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FETUS HEART RATE; FOLLOW UP; GENE EXPRESSION; GESTATIONAL SAC; HEART CONTRACTION; HORMONAL THERAPY; HORMONE BLOOD LEVEL; HORMONE SUBSTITUTION; HUMAN; HYSTEROSCOPY; IMMUNOMAGNETIC ISOLATION; INTRAUTERINE CONTRACEPTIVE DEVICE; LAPAROSCOPY; M MODE ECHOCARDIOGRAPHY; MENSTRUAL CYCLE; MENSTRUATION; ORGAN SIZE; OVARY FOLLICLE; PREGNANCY; REPEAT PROCEDURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPEROVULATION; SYSTOLE; TISSUE REGENERATION; TRANSABDOMINAL ECHOGRAPHY; TRANSVAGINAL ECHOGRAPHY; UTERUS BLOOD FLOW; UTERUS SYNECHIA; WITHDRAWAL BLEEDING; YOLK SAC;

EID: 79960204749     PISSN: 09741208     EISSN: 19984766     Source Type: Journal    
DOI: 10.4103/0974-1208.82360     Document Type: Article

References (22)

1. Tepper OM, Sealove BA, Murayama T, Asahara T. Newly emerging concepts in blood vessel growth: Recent discovery of endothelial progenitor cells and their function in tissue regeneration. J Investig Med 2003;51:353-9. (Pubitemid 37517620)
2. Jiang S, Walker L, Afentoulis M, Anderson DA, Jauron-Mills L, Corless CL, et al. Transplanted human bone marrow contributes to vascular endothelium. Proc Natl Acad Sci U S A 2004;101:16891-6. (Pubitemid 39601334)
3. Urbich C, Dimmeler S. Endothelial progenitor cells: Characterization and role in vascular biology. Circ Res 2004;95:343-53. (Pubitemid 39100452)
4. Peters BA, Diaz LA, Polyak K, Meszler L, Romans K, Guinan EC, et al. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med 2005;11:261-2. (Pubitemid 40460552)
5. Taylor HS. Endometrial cells derived from donor stem cells in bone marrow transplant recipients. JAMA 2004;292:81-5. (Pubitemid 38923797)
6. Yin AH, Miraglia S, Zanjani ED, Almeida-Porada G, Ogawa M, Leary AG, et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997;90:5002-12. (Pubitemid 28007217)
7. Miraglia S, Godfrey W, Yin AH, Atkins K, Warnke R, Holden JT, et al. A novel five-transmembrane hematopoietic stem cell antigen: Isolation, characterization, and molecular cloning. Blood 1997;90:5013-21. (Pubitemid 28007218)
8. Piechaczek C. CD133. J Biol Regul Homeost Agents 2001;15:101-2. (Pubitemid 32492736)
9. Bhring HJ, Seiffert M, Bock TA, Scheding S, Thiel A, Scheffold A, et al. Expression of novel surface antigens on early hematopoietic cells. Ann N Y Acad Sci 1999;872:25-38.
10. Gallacher L, Murdoch B, Wu DM, Karanu FN, Keeney M, Bhatia M. Isolation and characterization of human CD34(-)Lin(-) and CD34(+)Lin(-) hematopoietic stem cells using cell surface markers AC133 and CD7. Blood 2000;95:2813-20. (Pubitemid 30235890)
11. de Wynter EA, Buck D, Hart C, Heywood R, Coutinho LH, Clayton A, et al. CD34+AC133+ cells isolated from cord blood are highly enriched in long-term culture-initiating cells, NOD/SCID-repopulating cells and dendritic cell progenitors. Stem Cells 1998;16:387-96. (Pubitemid 28524504)
12. Gehling UM, Ergn S, Schumacher U, Wagener C, Pantel K, Otte M, et al. In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood 2000;95:3106-12.
13. Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 2000;95:952-8. (Pubitemid 30062717)
14. Uchida N, Buck DW, He D, Reitsma MJ, Masek M, Phan TV, et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A 2000;97:14720-5. (Pubitemid 32016642)
15. Cummings BJ, Uchida N, Tamaki SJ, Salazar DL, Hooshmand M, Summers R, et al. Human neural stem cells differentiate and promote locometer recovery in spinal cord-injured mice. Proc Natl Acad Sci U S A 2005;102:14069-74. (Pubitemid 41377704)
16. Bussolati B, Bruno S, Grange C, Buttiglieri S, Deregibus MC, Cantino D, et al Isolation of renal progenitor cells from adult human kidney. Am J Pathol 2005;166:545-55 (Pubitemid 40189050)
17. Yu DM, Wong YM, Cheong Y, Xia E, Li TC. Asherman syndrome - one century later. Fertil Steril 2008;89:759-79. (Pubitemid 351491241)
18. Valle RF, Scirra JJ. Intrauterine adhesions: Hysteroscopic diagnosis, classification, treatment and reproductive outcome. Am J Obstet Gynecol 1988;158:1459-70.
19. Meng X, Ichim TE, Zhong J, Rogers A, Yin Z, Jackson J, et al. Endometrial regenerative cells: A novel stem cell population. J Transl Med 2007;5:57.
20. Du H, Taylor HS. Contribution of bone marrow-derived stem cells to endometrium and endometriosis. Stem Cells 2007;25:2082-6. (Pubitemid 47258186)
21. Narkar M, Kholkute S, Chitlange S, Nandedkar T. Expression of steroid hormone receptors, proliferation and apoptotic markers in primate endometrium. Mol Cell Endocrinol 2006;246:107-13. (Pubitemid 43238403)
22. Song M, Ramaswamy S, Ramachandran S, Flowers LC, Horowitz IR, Rock JA, et al. Angiogenic role for glycodelin in tumorigenesis. Proc Natl Acad Sci U S A 2001;98:9265-70. (Pubitemid 32743905)