Effects of two simulated oxytetracycline dosing regimens on horizontal transfer of antimicrobial resistance plasmids in an in vitro pharmacodynamic model

American Journal of Veterinary Research

Volumn 72, Issue 7, 2011, Pages 877-883

  Lubbers, Brian V ^a   Peterson, Greg J ^a,b   Narayanan, Sanjeev K ^a   Havel, James A ^a   Coetzee, Johann F ^a   Apley, Michael D ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b KANSAS DEPARTMENT OF HEALTH AND ENVIRONMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXYTETRACYCLINE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EXPOSURE; DRUG PROTEIN BINDING; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMID; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; VERTICAL TRANSMISSION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CONJUGATION, GENETIC; ESCHERICHIA COLI; GENE TRANSFER, HORIZONTAL; MICROBIAL SENSITIVITY TESTS; OXYTETRACYCLINE; PLASMIDS; SALMONELLA TYPHIMURIUM; SELECTION, GENETIC; TETRACYCLINE RESISTANCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM;

EID: 79960196979     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.72.7.877     Document Type: Article

References (30)

1. Spellberg B. Dr. William H. Stewart: mistaken or maligned? (lett) Clin Infect Dis 2008;47:294.
2. Phillips I, Casewell M, Cox T, et al. Does the use of antibiotics in food animals pose a risk to human health? A critical review of published data. J Antimicrob Chemother 2004;53:28-52.
3. Tenover FC. Development and spread of bacterial resistance to antimicrobial agents: an overview. Clin Infect Dis 2001;33(suppl 3):108-115.
4. Blaser JM, Stone BB, Groner MC, et al. Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance. Antimicrob Agents Chemother 1987;3:1054-1060.
5. Jumbe N, Louie A, Leary R, et al. Application of a mathematical model to prevent in vivo amplification of antibioticresistant bacterial populations during therapy. J Clin Invest 2003;112:275-285.
6. Thomas JK, Forrest A, Bhavnani SM, et al. Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy. Antimicrob Agents Chemother 1998;42:521-527.
7. AVMA. Judicious therapeutic use of antimicrobials. Available at: www.avma.org/issues/policy/jtua.asp. Accessed Aug 27, 2009.
8. Courvalin P. Can pharmacokinetic-pharmacodynamic parameters provide dosing regimens that are less vulnerable to resistance? Clin Microbiol Infect 2008;14:989-994.
9. Firsov AA, Smirnova MV, Lubenko IY, et al. Testing the mutant selection window hypothesis with Staphylococcus aureus exposed to daptomycin and vancomycin in an in vitro dynamic model. J Antimicrob Chemother 2006;58:1185-1192.
10. Olofsson SK, Marcusson LL, Lindgren PK, et al. Selection of ciprofloxacin resistance in Escherichia coli in an in vitro kinetic model: relation between drug exposure and mutant prevention concentration. J Antimicrob Chemother 2006;57:1116-1121.
11. Zhao X, Drlica K. Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies. J Infect Dis 2001;185:561-565.
12. Schwarz S, Chaslus-Dancla E. Use of antimicrobials in veterinary medicine and mechanisms of resistance. Vet Res 2001;32:201-225.
13. Doucet-Populaire F, Trieu-Cuot P, Dosbaa I, et al. Inducible transfer of conjugative transposon Tn1545 from Enterococcus faecalis to Listeria monocytogenes in the digestive tracts of gnotobiotic mice. Antimicrob Agents Chemother 1991;35:185-187.
14. Giles WP, Benson AK, Olson ME, et al. DNA sequence analysis of regions surrounding blaCMY-2 from multiple Salmonella plasmid backbones. Antimicrob Agents Chemother 2004;48:2845-2852.
15. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals: approved standard. M31-A2.2nd ed. Wayne, NJ: Clinical and Laboratory Standards Institute, 2002.
16. Grasso S, Meinardi G, DeCarneri I, et al. New in vitro model to study the effect of antibiotic concentration and rate of elimination on antibacterial activity. Antimicrob Agents Chemother 1978;13:570-576.
17. Murakawa T, Sakamoto H, Hirose T, et al. New in vitro model for evaluating bactericidal efficacy of antibiotics. Antimicrob Agents Chemother 1980;18:377-381.
18. Sanfilippo A, Morvillo E. An experimental model for the study of the antibacterial activity of the sulfonamides. Chemotherapy 1968;13:54-60.
19. Pijpers A, Schoevers EJ, Van Gogh H, et al. The pharmacokinetics of oxytetracycline following intravenous administration in healthy and diseased pigs. J Vet Pharmacol Ther 1990;13:320-326.
20. El Korchi G, Prats C, Arboix M, et al. Disposition of oxytetracycline in pigs after i.m. administration of two long-acting formulations. J Vet Pharmacol Ther 2001;24:247-250.
21. Blondeau JM, Hansen G, Metzler K, et al. The role of PK/PD parameters to avoid selection and increase of resistance: mutant prevention concentration. J Chemother 2004;16(suppl 3):1-19.
22. MacGowan AP, Bowker KE, Noel AR. Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection. Antimicrob Agents Chemother 2008;52:1401-1406.
23. Ryback MJ. Pharmacodynamics: relation to antimicrobial resistance. Am J Infect Control 2006;34:38-45.
24. Shoemaker NB, Vlamakis H, Hayes K, et al. Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon. Appl Environ Microb 2001;67:561-568.
25. Schjørring S, Struve C, Krogfelt KA. Transfer of antimicrobial resistance plasmids from Klebsiella pneumoniae to Escherichia coli in the mouse intestine. J Antimicrob Chemother 2008;62:1086-1093.
26. Showsh SA, Andrews RE Jr. Tetracycline enhances Tn916-mediated conjugal transfer. Plasmid 1992;28:213-224.
27. Torres OR, Korman RZ, Zahler SA, et al. The conjugative transposon Tn925: enhancement of conjugal transfer by tetracycline in Enterococcus faecalis and mobilization of chromosomal genes in Bacillus subtilis and E. faecalis. Mol Gen Genet 1991;225:395-400.
28. Loftin KA, Adams CD, Meyer MT, et al. Effects of ionic strength, temperature, and pH on degradation of selected antibiotics. J Environ Quality 2008;37:378-386.
29. Oxytetracycline monograph. In: Budavari S, ed. The Merck index. 11th ed. Rahway, NJ: Merck and Co Inc, 1989;1104.
30. Hirt H, Schlievert PM, Dunny GM. In vivo induction of virulence and antibiotic resistance transfer in Enterococcus faecalis mediated by the sex pheromone-sensing system of pCF10. Infect Immun 2002;70:716-723.