Can pharmacokinetic-pharmacodynamic parameters provide dosing regimens that are less vulnerable to resistance?

Clinical Microbiology and Infection

Volumn 14, Issue 11, 2008, Pages 989-994

  Courvalin, P ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Antibiotic; Bacterium; Pharmacodynamic; Pharmacokinetic; Resistance; Review

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CHLORAMPHENICOL; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); GAMMA GLUTAMYLTRANSFERASE; MITOMYCIN C; PENICILLIN G; PEPTIDOGLYCAN; PNEUMOCOCCUS VACCINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; STREPTOMYCIN; SULFONAMIDE; TEICOPLANIN; TETRACYCLINE; TRIMETHOPRIM; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIAL TRANSMISSION; CHROMOSOME; DNA REPLICATION; DRUG DOSE REGIMEN; GENE MUTATION; GENE TRANSLOCATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HORIZONTAL GENE TRANSFER; HOST SUSCEPTIBILITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACODYNAMICS; PHARMACOKINETICS; PLASMID; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REPLICON; REVIEW; TRANSPOSON;

BACTERIA (MICROORGANISMS);

EID: 56849110070     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2008.02081.x     Document Type: Review

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