Twin study on transplacental-acquired antibodies and attention deficit/hyperactivity disorder - A pilot study

Journal of Neuroimmunology

Volumn 236, Issue 1-2, 2011, Pages 72-75

  Bilenberg, Niels ^a   Hougaard, David ^b   Norgaard Pedersen, Bent ^b   Nordenbæk, Claudia Maria ^a   Olsen, Jørn ^c  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

ADHD; Etiology; Infectious Agents; Twins

Indexed keywords

MATERNAL ANTIBODY; PNEUMOCOCCUS POLYSACCHARIDE;

ADOLESCENT; ANTIBODY BLOOD LEVEL; ARTICLE; ATTENTION DEFICIT DISORDER; BLOOD ANALYSIS; CHILD; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MONOZYGOTIC TWINS; NEWBORN; PILOT STUDY; PLACENTAL TRANSFER; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; TWIN DISCORDANCE;

ADOLESCENT; ANTIGENS, BACTERIAL; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BACTERIAL CAPSULES; CHILD; CHILD, PRESCHOOL; DISEASES IN TWINS; FEMALE; HUMANS; MALE; MATERNAL-FETAL EXCHANGE; PILOT PROJECTS; PREGNANCY; QUESTIONNAIRES; STREPTOCOCCUS PNEUMONIAE;

EID: 79960168705     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2011.04.012     Document Type: Article

References (32)

1. Achenbach T.M.R.L.A. Manual for ASEBA School-Age Forms & Profiles University of Vermont, Research Center for Children 2001, Youth & Families, Burlington, VT.
2. American Psychiatric Association Diagnostic and statistical manual mental disorders, 4th edition (DSM-IV) 1994, Washington, DC. 4th ed.
3. Bilenberg N. The Child Behavior Checklist (CBCL) and related material: standardization and validation in Danish population based and clinically based samples. Acta Psychiatr. Scand. 1999, 100:2-52.
4. Bilenberg N., Petersen D.J., Hoerder K., Gillberg C. The prevalence of child-psychiatric disorders among 8-9-year-old children in Danish mainstream schools. Acta Psychiatr. Scand. 2005, 111(1):59-67.
5. Braunschweig D., Ashwood P., Krakowiak P., Hertz-Picciotto I., Hansen R., Croen L.A., Pessah I.N., Van de W.J. "Autism: maternally derived antibodies specific for fetal brain proteins". Neurotoxicology 2008, 29(2):226-231.
6. Brown A.S., Derkits E.J. Prenatal infection and schizophrenia: a review of epidemiologic and translational studies. Am. J. Psychiatry 2010, 167(3):261-280.
7. Brown A.S., Begg M.D., Gravenstein S., Schaefer C.A., Wyatt R.J., Bresnahan M., Babulas V.P., Susser E.S. Serologic evidence of prenatal influenza in the etiology of schizophrenia. Arch. Gen. Psychiatry 2004, 61(8):774-780.
8. Brown A.S., Schaefer C.A., Quesenberry C.P., Liu L., Babulas V.P., Susser E.S. Maternal exposure to toxoplasmosis and risk of schizophrenia in adult offspring. Am. J. Psychiatry 2005, 162(4):767-773.
9. Buka S.L., Tsuang M.T., Torrey E.F., Klebanoff M.A., Bernstein D., Yolken R.H. Maternal infections and subsequent psychosis among offspring. Arch. Gen. Psychiatry 2001, 58(11):1032-1037.
10. Diamond B., Huerta P.T., Mina-Osorio P., Kowal C., Volpe B.T. Losing your nerves? Maybe it's the antibodies. Nat. Rev. Immunol. 2009, 9(6):449-456.
11. Earley M.C., Vogt R.F., Shapiro H.M., Mandy F.F., Kellar K.L., Bellisario R., Pass K.A., Marti G.E., Stewart C.C., Hannon W.H. Report from a workshop on multianalyte microsphere assays. Cytometry 2002, 50(5):239-242.
12. Faraone S.V., Sergeant J., Gillberg C., Biederman J. The worldwide prevalence of ADHD: is it an American condition?. World Psychiatry. 2003, 2(2):104-113.
13. Goodman R., Renfrew D., Mullick M. Predicting type of psychiatric disorder from Strengths and Difficulties Questionnaire (SDQ) scores in child mental health clinics in London and Dhaka. Eur. Child Adolesc. Psychiatry 2000, 9(2):129-134.
14. Hayes B., Sharif F. Behavioural and emotional outcome of very low birth weight infants-literature review. J. Matern. Fetal Neonatal Med. 2009, 22(10):849-856.
15. Knudsen L.B., Olsen J. The Danish Medical Birth Registry. Dan. Med. Bull. 1998, 45(3):320-323.
16. Mednick S.A., Machon R.A., Huttunen M.O., Bonett D. Adult schizophrenia following prenatal exposure to an influenza epidemic. Arch. Gen. Psychiatry 1988, 45(2):189-192.
17. Mortensen P.B., Norgaard-Pedersen B., Waltoft B.L., Sorensen T.L., Hougaard D., Torrey E.F., Yolken R.H. Toxoplasma gondii as a risk factor for early-onset schizophrenia: analysis of filter paper blood samples obtained at birth. Biol. Psychiatry 2007, 61(5):688-693.
18. Mortensen P.B., Pedersen C.B., Hougaard D.M., Norgaard-Petersen B., Mors O., Borglum A.D., Yolken R.H. A Danish National Birth Cohort study of maternal HSV-2 antibodies as a risk factor for schizophrenia in their offspring. Schizophr. Res. 2010, 122(1-3):257-263.
19. Nahmias A.J., Nahmias S.B., Danielsson D. The possible role of transplacentally-acquired antibodies to infectious agents, with molecular mimicry to nervous system sialic acid epitopes, as causes of neuromental disorders: prevention and vaccine implications. Clin. Dev. Immunol. 2006, 13(2-4):167-183.
20. Nordenbeck, C., Kyvik, K., Skytthe, A., Bilenberg, N., in press. "Efficiency of a small size screening instrument in identifying children with autism spectrum disorders in a large population of twins". Epidemiol. Res. Int.
21. Obel C., Linnet K.M., Henriksen T.B., Rodriguez A., Jarvelin M.R., Kotimaa A., Moilanen I., Ebeling H., Bilenberg N., Taanila A., Ye G., Olsen J. "Smoking during pregnancy and hyperactivity-inattention in the offspring - comparing results from three Nordic cohorts". Int. J. Epidemiol. 2009, 38(3):698-705.
22. Ornoy, A. 2002, "[The effects of Cytomegalic virus (CMV) infection during pregnancy on the developing human fetus]", Harefuah, vol. 141, no. 6, pp. 565-568, 577.
23. Petersen D.J., Bilenberg N., Hoerder K., Gillberg C. The population prevalence of child psychiatric disorders in Danish 8- to 9-year-old children. Eur. Child Adolesc. Psychiatry 2006, 15(2):71-78.
24. Rietveld M.J., Hudziak J.J., Bartels M., van Beijsterveldt C.E., Boomsma D.I. Heritability of attention problems in children: longitudinal results from a study of twins, age 3 to 12. J. Child Psychol. Psychiatry 2004, 45(3):577-588.
25. Sanchez-Carpintero R., Albesa S.A., Crespo N., Villoslada P., Narbona J. A preliminary study of the frequency of anti-basal ganglia antibodies and streptococcal infection in attention deficit/hyperactivity disorder. J. Neurol. 2009, 256(7):1103-1108.
26. Singer H.S., Morris C.M., Gause C.D., Gillin P.K., Crawford S., Zimmerman A.W. Antibodies against fetal brain in sera of mothers with autistic children. J. Neuroimmunol. 2008, 194(1-2):165-172.
27. Skogstrand K., Thorsen P., Norgaard-Pedersen B., Schendel D.E., Sorensen L.C., Hougaard D.M. Simultaneous measurement of 25 inflammatory markers and neurotrophins in neonatal dried blood spots by immunoassay with xMAP technology. Clin. Chem. 2005, 51(10):1854-1866.
28. Skytthe A., Kyvik K., Bathum L., Holm N., Vaupel J.W., Christensen K. The Danish Twin Registry in the new millennium. Twin Res. Hum. Genet. 2006, 9(6):763-771.
29. SPSS. [17.0]. 2010. Chicago, Illinois 60606, SPSS Inc. Ref Type: Computer Program.
30. Swanson J.M., Kinsbourne M., Nigg J., Lanphear B., Stefanatos G.A., Volkow N., Taylor E., Casey B.J., Castellanos F.X., Wadhwa P.D. Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis. Neuropsychol. Rev. 2007, 17(1):39-59.
31. van Loo K.M., Martens G.J. "Genetic and environmental factors in complex neurodevelopmental disorders". Curr.Genomics 2007, 8(7):429-444.
32. Webster W.S. Teratogen update: congenital rubella. Teratology 1998, 58(1):13-23.