The infusion of opioids during terminal withdrawal of mechanical ventilation in the medical intensive care unit

Journal of Pain and Symptom Management

Volumn 42, Issue 1, 2011, Pages 44-51

  Mazer, Mark A ^a,c   Alligood, Chad M ^c   Wu, Qiang ^b  

^a EAST CAROLINA UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c PITT COUNTY MEMORIAL HOSPITAL   (United States)

Author keywords

guidelines; mechanical ventilation; Opioids; palliative care; terminal care; withholding treatment

Indexed keywords

MORPHINE;

ACUTE LUNG INJURY; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL TRIAL; COMA; DEATH; EXTUBATION; FEMALE; HUMAN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORBIDITY; OUTCOME ASSESSMENT; PROSPECTIVE STUDY; RESPIRATORY FAILURE; RESUSCITATION; SEPSIS; TERMINALLY ILL PATIENT; TREATMENT WITHDRAWAL;

ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; EUTHANASIA, PASSIVE; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; MORPHINE; PAIN; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; WITHHOLDING TREATMENT;

EID: 79960146005     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2010.10.256     Document Type: Article

References (29)

1. T.J. Prendergast, M.T. Classens, and J.M. Luce A national survey of end of life care for critically ill patients Am J Respir Crit Care Med 158 1998 1163 1167 (Pubitemid 28489017)
2. T.J. Prendergast, and J.M. Luce Increasing incidence of withholding and withdrawal of life support from the critically ill Am J Respir Crit Care Med 155 1997 15 20 (Pubitemid 27053134)
3. C.L. Sprung, S.L. Cohen, and P. Sjokvist End-of-life practices in European intensive care units: the Ethicus Study JAMA 290 2003 790 797 (Pubitemid 37432956)
4. C.L. Sprung, D. Ledoux, and H.H. Bulow Relieving suffering or intentionally hastening death: where do you draw the line? Crit Care Med 36 2008 8 13
5. G.G. Wood, and E. Martin Withholding and withdrawing life-sustaining therapy in a Canadian intensive care unit Can J Anaesth 42 1995 186 191
6. K. Faber-Langendoen, and P.N. Lanken Dying patients in the intensive care unit: forgoing treatment, maintaining care Ann Intern Med 133 2000 886 893
7. R.D. Truog, A.F.M. Cist, and S.E. Brackett Recommendations for end of life care in the intensive care unit: the Ethics Committee of the Society of Critical Care Medicine Crit Care Med 29 2001 2332 2348 (Pubitemid 34038168)
8. J. Jacobi, G.L. Fraser, and D.B. Coursin Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult Crit Care Med 30 2002 119 141 (Pubitemid 34112188)
9. R.D. Truog, M.L. Campbell, and J.R. Curtis Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American Academy of Critical Care Medicine Crit Care Med 36 2008 953 963
10. K. Faber-Langendoen The clinical management of dying patients receiving mechanical ventilation. A survey of physician practice Chest 106 1994 880 888 (Pubitemid 24278899)
11. R.P. George Lethal opioids or dangerous prescribers? Palliat Med 21 2007 77 80
12. The SUPPORT Principal Investigators A controlled trial to improve care for seriously ill hospitalized patients: the study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT) JAMA 274 1996 1591 1598
13. J.D. Chan, P.D. Treece, and R.A. Engleberg Narcotic and benzodiazepine use after withdrawal of life support Chest 126 2004 286 293
14. M.J. Edwards Opioids and benzodiazepines appear paradoxically to delay inevitable death after ventilator withdrawal J Palliat Care 21 2005 299 302 (Pubitemid 43116692)
15. M. Campbell How to withdraw mechanical ventilation: a systematic review of the literature AACN Adv Crit Care 4 2007 397 403
16. J.F. Payen, O. Bru, and J.L. Bosson Assessing pain in critically ill sedated patients by using a behavioral pain scale Crit Care Med 29 2001 2258 2263 (Pubitemid 34038155)
17. K. Faber-Langendoen, and D. Bartels Process of forgoing life-sustaining treatment in a university hospital: an empirical study Crit Care Med 20 1992 570 577
18. S.A. Mayer, and S.B. Kossoff Withdrawal of life support in the neurological intensive care unit Neurology 52 1999 1602 1609 (Pubitemid 29220634)
19. B.J. Daly, D. Thomas, and M.A. Dyer Procedures used in withdrawal of mechanical ventilation Am J Crit Care 5 1996 331 338 (Pubitemid 126484550)
20. M.L. Campbell, K.S. Bizek, and M. Thill Patient responses during rapid terminal weaning from mechanical ventilation: prospective study Crit Care Med 27 1999 73 77 (Pubitemid 29052817)
21. M. Ankrom, L. Zelesnick, and I. Barofsky Elective discontinuation of life sustaining mechanical ventilation on a chronic ventilator unit J Am Geriatr Soc 49 2001 1549 1554 (Pubitemid 33051410)
22. S. O'Mahony, M. McHugh, L. Zallman, and P. Selwyn Ventilator withdrawal: procedures and outcomes J Pain Symptom Manage 26 2003 954 961
23. G.M. Rocker, D.K. Heyland, and D.J. Cook Most critically ill patients are perceived to die in comfort during withdrawal of life support: a Canadian multicentre study Can J Anaesth 51 2004 623 630 (Pubitemid 38867929)
24. M.C. Wilson, N.G. Smedira, C. Fink, J.A. McDowell, and J.M. Luce Ordering and administration of sedatives and analgesics during the withholding and withdrawal of life support from critically ill patients JAMA 267 1992 949 953
25. S.P. Keenan, K.D. Busche, and L.M. Chen A retrospective review of a large cohort of patients undergoing the process of withholding or withdrawal of life support Crit Care Med 25 1997 1324 1331 (Pubitemid 27347296)
26. R. Hall, and G.M. Rocker End-of-life care in the ICU: treatments provided when life support was or was not withdrawn Chest 118 2000 1424 1430
27. B. Estfan, F. Mahmoud, and P. Shaheen Respiratory function during parenteral opioid titration for cancer pain Palliat Med 21 2007 81 86 (Pubitemid 46455833)
28. C. Tishelman, L.-M. Petersson, L. Degner, and M. Sprangers Symptom prevalence, intensity and distress in patients with inoperable lung cancer in relation to time of death J Clin Oncol 25 2007 5381 5389 (Pubitemid 350232213)
29. M. Campbell, T. Templin, and J. Walch A respiratory distress observation scale for patients unable to self-report dyspnea J Palliat Med 13 2010 285 289