A conjugate of pyridine-4-aldoxime and atropine as a potential antidote against organophosphorus compounds poisoning

Acta Biochimica Polonica

Volumn 58, Issue 2, 2011, Pages 193-198

  Lovrić, Jasna ^a   Berend, Suzana ^b   Vrdoljak, Ana Lucić ^b   Radić, Božica ^b   Katalinić, Maja ^b   Kovarik, Zrinka ^b   Želježić, Davor ^b   Kopjar, Nevenka ^b   Rast, Slavko ^c   Mesić, Milan ^c  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

^c Galapagos Research Centre doo   (Croatia)

Author keywords

Antidotal potential; Atropine; Genotoxicity; Organophosphates; Pyridine 4 aldoxime

Indexed keywords

8 (4 (4 ( (HYDROXYIMINO)METHYL) 1 PYRIDINIUMYL)BUTYL) 3 ((3 HYDROXY 2 PHENYLPROPANOYL)OXY) 8 METHYL 8 AZONIABICYCLO(3.2.1)OCTANE; 8-(4-(4-(-(HYDROXYIMINO)METHYL)-1-PYRIDINIUMYL)BUTYL)-3-((3-HYDROXY-2-PHENYLPROPANOYL)OXY)-8-METHYL-8-AZONIABICYCLO(3.2.1)OCTANE; ACETYLCHOLINESTERASE; ANTIDOTE; ATROPINE DERIVATIVE; CHOLINESTERASE INHIBITOR; CHOLINESTERASE REACTIVATOR; ORGANOPHOSPHATE; PARAOXON; PRALIDOXIME; SOMAN; TABUN;

ADULT; ANIMAL; ARTICLE; CELL DEATH; CELL SURVIVAL; DRUG EFFECT; ENZYME ASSAY; ENZYMOLOGY; ERYTHROCYTE; HUMAN; LYMPHOCYTE; MALE; MOUSE; SYNTHESIS;

ACETYLCHOLINESTERASE; ADULT; ANIMALS; ANTIDOTES; ATROPINE DERIVATIVES; CELL DEATH; CELL SURVIVAL; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; ENZYME ASSAYS; ERYTHROCYTES; HUMANS; LYMPHOCYTES; MALE; MICE; PARAOXON; PHOSPHORIC ACID ESTERS; PRALIDOXIME COMPOUNDS; SOMAN;

ANIMALIA; MUS;

EID: 79960141269     PISSN: 0001527X     EISSN: 1734154X     Source Type: Journal    
DOI: None     Document Type: Article

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