A method to calculate binding equilibrium concentrations in the allosteric ternary complex model that supports ligand depletion

Mathematical Biosciences

Volumn 232, Issue 2, 2011, Pages 135-141

  Gnacadja, Gilles ^a  

^a AMGEN INC   (United States)

Author keywords

Allosteric ternary complex model; Binding equilibrium; Ligand depletion

Indexed keywords

BINDING EQUILIBRIA; CALCULATION METHODS; COOPERATIVITY FACTORS; EQUILIBRIUM CONCENTRATION; EQUILIBRIUM DISSOCIATION CONSTANT; EXPLICIT FORMULA; LIGAND DEPLETION; NUMERICAL ALGORITHMS; TERNARY COMPLEX;

ALGORITHMS; DISSOCIATION; LIGANDS;

EQUILIBRIUM CONSTANTS;

LIGAND;

ALGORITHM; LIGAND; NUMERICAL MODEL;

ALGORITHM; ALLOSTERIC TERNARY COMPLEX MODEL; ALLOSTERISM; ARTICLE; DISSOCIATION CONSTANT; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; METHODOLOGY; QUANTITATIVE ANALYSIS;

ALGORITHMS; BINDING, COMPETITIVE; KINETICS; LIGANDS; MODELS, CHEMICAL; PHARMACOLOGY; THERMODYNAMICS;

EID: 79960109943     PISSN: 00255564     EISSN: 18793134     Source Type: Journal    
DOI: 10.1016/j.mbs.2011.05.003     Document Type: Article

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