Investigation on the pharmacological profile of antimony(III) complexes with hydroxyquinoline derivatives: Anti-trypanosomal activity and cytotoxicity against human leukemia cell lines

BioMetals

Volumn 24, Issue 4, 2011, Pages 595-601

  Reis, Débora C ^a   Pinto, Mauro C X ^a   Souza Fagundes, Elaine M ^a   Rocha, Lucas F ^b   Pereira, Valéria R A ^b   Melo, Cristiane M L ^b   Beraldo, Heloisa ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

5 Chloro 7 iodo 8 hydroxyquinoline (clioquinol); 5 Chloro 8 hydroxyquinoline; 8 Hydroxyquinoline; Anti trypanosomal; Antimony(III) complexes; Cytotoxicity; Leukemia

Indexed keywords

ANTIMONY DERIVATIVE; BIS(5 CHLORO 7 IODO 8 HYDROXYQUINOLINATO)(CHLORO)ANTIMONY; BIS(5 CHLORO 8 HYDROXYQUINOLINATO)(CHLORO)ANTIMONY; BIS(8 HYDROXYQUINOLINATO)(CHLORO)ANTIMONY; CLIOQUINOL; QUINOLINOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; EPIMASTIGOTE; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; MALE; MOUSE; NONHUMAN; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ANIMALS; ANTIMONY; ANTINEOPLASTIC AGENTS; ANTIPROTOZOAL AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; HYDROXYQUINOLINES; MALE; MICE; MICE, INBRED BALB C; ORGANOMETALLIC COMPOUNDS; PARASITIC SENSITIVITY TESTS; SPLEEN; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 79960106134     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-011-9407-8     Document Type: Article

References (18)

1. W Ding B Liu JL Vaught H Yamauchi SE Lind 2005 Anticancer activity of the antibiotic clioquinol Cancer Res 65 3389 3395 15833873 10.1158/0008-5472.CAN- 04-4385 1:CAS:528:DC%2BD2MXjt1yrsLs%3D (Pubitemid 41060687)
2. G Filiz A Caragounis L Bica T Du CL Masters PJ Crouch AR White 2008 Clioquinol inhibits peroxide-mediated toxicity through up-regulation of phosphoinositol-3-kinase and inhibition of p53 activity Int J Biochem Cell Biol 40 1030 1042 18160328 10.1016/j.biocel.2007.11.003 1:CAS:528: DC%2BD1cXjtVektb8%3D
3. BL Herwaldt 1999 Leishmaniasis Lancet 354 1191 1199 10513726 10.1016/S0140-6736(98)10178-2 1:STN:280:DyaK1MvktFyrtg%3D%3D (Pubitemid 29460458)
4. T Mosmann 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 55 63 6606682 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D (Pubitemid 14203433)
5. JC Mottram DR Brooks GH Coombs 1998 Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions Curr Opin Microbiol 1 455 460 10066510 10.1016/S1369-5274(98)80065-9 1:CAS:528:DyaK1cXlslGnsb8%3D (Pubitemid 128423262)
6. Nakamoto K (1970) Infrared spectra of inorganic and coordination compounds, 2nd edn. Willey-Interscience, New York, p 327
7. J Nordenberg A Novogrodsky E Beery M Patia L Wasserman A Warshawsky 1990 Anti-proliferative effects and phenotypic alterations induced by 8-hydroxyquinoline in melanoma cell lines Eur J Cancer Clin Oncol 26 905 907 10.1016/0277-5379(90)90197-2 1:CAS:528:DyaK3MXit1SrtL8%3D
8. VRA Pereira VMB Lorena AP Galvão da Silva EM Coutinho ED Silva AGP Ferreira P Miranda MA Krieger S Goldenberg MBP Soares R Correa-Oliveira Y Gomes 2004 Immunization with cytoplasmic repetitive antigen and flagellar repetitive antigen of Trypanosoma cruzi stimulates a cellular immune response in mice Parasitology 129 563 570 15552401 10.1017/S0031182004006043 1:CAS:528: DC%2BD2cXotFSgsL8%3D (Pubitemid 39473006)
9. DC Reis MCX Pinto EM Souza-Fagundes SMSV Wardell JL Wardell H Beraldo 2010 Antimony(III) complexes with 2-benzoylpyridine-derived thiosemicarbazones: cytotoxicity against human leukemia cell lines Eur J Med Chem 45 3904 3910 20576328 10.1016/j.ejmech.2010.05.044 1:CAS:528:DC%2BC3cXpvFKhs7Y%3D
10. ERT Tiekink 2002 Antimony and bismuth compounds in oncology Crit Rev Oncol/Hematol 42 217 224 10.1016/S1040-8428(01)00217-7 (Pubitemid 34618518)
11. LTD Tonin MR Panice CV Nakamura KJP Rocha AO Santos T Ueda-Nakamura WF Costa M Sarragiotto 2010 Antitrypanosomal and antileishmanial activities of novel N-alkyl-(1-phenylsubstituted-β-carboline)-3-carboxamides Biomed Pharmacother 64 386 389 20382497 10.1016/j.biopha.2010.02.006 1:CAS:528:DC%2BC3cXos1yksb0%3D
12. E Ulukaya M Colakogullari EJ Wood 2004 Interference by anti-cancer chemotherapeutic agents in the MTT-tumor chemosensitivity assay Chemotherapy 50 43 50 15084806 10.1159/000077285 1:CAS:528:DC%2BD2cXjtV2rtrc%3D (Pubitemid 38490200)
13. CC Wagner S Calvo MH Torre EJ Baran 2007 Vibrational spectra of clioquinol and its Cu(II)complex J Raman Spectrosc 38 373 376 10.1002/jrs.1654 1:CAS:528:DC%2BD2sXltValtrY%3D
14. Woster PM (2007) Antiprotozoal agents (African trypanosomiasis, Chagas disease, and leishmaniasis. In: Desai MC, Plattner JJ (eds) Comprehensive medicinal chemistry II. Elsevier Science, Oxford, pp 815-843
15. HD Yin J Zhai 2009 Synthesis, characterizations and crystal structures of antimony(III) complexes with nitrogen-containing ligands Inorg Chim Acta 362 339 345 10.1016/j.ica.2008.04.012 1:CAS:528:DC%2BD1cXhsFCjsb7L
16. H Yu Y Zhou SE Linf WQ Ding 2009 Clioquinol targets zinc to lysosomes in human cancer cells Biochem J 417 133 139 18764784 10.1042/BJ20081421 1:CAS:528:DC%2BD1cXhsV2lt7zN
17. S Yurdakul K Arýcý 2004 Synthesis and vibrational spectra of metal halide complexes of 8-hydroxyquinoline in relation to their structures J Mol Struct 691 45 49 10.1016/j.molstruc.2003.11.014 1:CAS:528: DC%2BD2cXhsFeksL0%3D (Pubitemid 38251520)
18. S Zhai L Yang QC Cui Y Sun QP Dou B Yan 2010 Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells J Biol Inorg Chem 15 259 269 19809836 10.1007/s00775-009-0594-5 1:CAS:528: DC%2BC3cXjsFWguw%3D%3D