Drug mimic induced conformational changes in model polymer-drug conjugates characterized by small-angle neutron scattering

Biomacromolecules

Volumn 11, Issue 8, 2010, Pages 1978-1982

  Paul, A ^a   James, C ^a   Heenan, R K ^b   Schweins, R ^c  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b RUTHERFORD APPLETON LABORATORY   (United Kingdom)

^c INSTITUT LAUE LANGEVIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-CANCER THERAPEUTICS; AROMATIC MOLECULES; CONFORMATIONAL CHANGE; CONJUGATE STRUCTURES; DETAILED MODELING; DRUG-CONJUGATES; MODEL DRUGS; RANDOM COIL; SIDE-CHAIN; SMALL-ANGLE NEUTRON SCATTERING; SOLUTION CONFORMATIONS; SOLUTION PROPERTY; TYPE STRUCTURES;

AROMATIC HYDROCARBONS; CONFORMATIONS; NEUTRON SCATTERING;

POLYMERS;

ACRYLAMIDE DERIVATIVE; DOXORUBICIN; POLY[N (2 HYDROXYPROPYLMETHACRYLAMIDE)]; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; DRUG CONFORMATION; DRUG CONJUGATION; MORPHOLOGY; NEUTRON SCATTERING; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; DOXORUBICIN; MODELS, MOLECULAR; MOLECULAR MIMICRY; NEUTRON DIFFRACTION; SCATTERING, SMALL ANGLE;

EID: 77955583484     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm1003338     Document Type: Article

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