Does medication adherence lower medicare spending among beneficiaries with diabetes?

Health Services Research

Volumn 46, Issue 4, 2011, Pages 1180-1199

  Stuart, Bruce ^b   Davidoff, Amy ^b   Lopert, Ruth ^b   Shaffer, Thomas ^b   Samantha Shoemaker, J ^b   Lloyd, Jennifer ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

cost offsets; Diabetes; Medicare; medication adherence

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

AGED; ARTICLE; COST CONTROL; COST OF ILLNESS; DIABETES MELLITUS; DRUG UTILIZATION; FEMALE; HEALTH CARE COST; HUMAN; LONGITUDINAL STUDY; MALE; MEDICARE; PATIENT COMPLIANCE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; COMORBIDITY; COSTS AND COST ANALYSIS; DIABETES MELLITUS; DRUG UTILIZATION; FEMALE; HEALTH BEHAVIOR; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HEALTH STATUS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INSURANCE CLAIM REVIEW; MALE; MEDICARE; MEDICATION ADHERENCE; RESIDENCE CHARACTERISTICS; SEX FACTORS; SOCIOECONOMIC FACTORS; UNITED STATES;

EID: 79960089434     PISSN: 00179124     EISSN: 14756773     Source Type: Journal    
DOI: 10.1111/j.1475-6773.2011.01250.x     Document Type: Article

References (31)

1. American Diabetes Association. 2008. " Standards of Medical Care in Diabetes. Diabetes Care 31 (suppl 1): S12-54.
2. Balkrishnan, R., R. Rajagopalan, and, F. T. Camacho,. 2003. " Predictors of Medication Adherence and Associated Health Care Costs in an Older Population with Type 2 Diabetes Mellitus: A Longitudinal Cohort Study. Clinical Therapeutics 25: 2958-71. (Pubitemid 37510603)
3. Birkmeyer, G., and, H. G. Welch,. 2005. " Cost-Effectiveness of Full Medicare Coverage of Angiotensin-Converting Enzyme Inhibitors for Beneficiaries with Diabetes. Annals of Internal Medicine 143: 89-99.
4. Brandle, M., M. B. Davidson, D. L. Schriger, B. Lorber, and, W. H. Herman,. 2003. " Cost Effectiveness of Statin Therapy for the Primary Prevention of Major Coronary Events in Individuals with Type 2 Diabetes. Diabetes Care 26 (6): 1786-801.
5. Brown, A. F., C. M. Mangione, D. Saliba, and, C. A. Sarkisian,. 2003. " California Healthcare Foundation/American Geriatrics Society Panel on Improving Care for Elders with Diabetes: Guidelines for Improving the Care of the Older Person with Diabetes Mellitus. Journal of the American Geriatrics Society 51: S265-80.
6. Buccaneer Computer Systems and Services Inc. 2009. "Chronic Condition Warehouse User Manual" [accessed on June 15, 2009]. Available at http://ccwdata.org/downloads/CCW%20User%20Manual.pdf
7. Centers for Medicare and Medicaid Services (CMS). " Overview of the Medicare Current Beneficiary Survey " [accessed on December 14, 2009]. Available at http://www.cms.hhs.gov/mcbs
8. Chewning, B., 2006. " Commentary: The Healthy Adherer and the Placebo Effect. British Medical Journal 333: 18-9.
9. Coronary Drug Project Research Group. 1980. " Influence of Adherence to Treatment and Response of Cholesterol on Mortality in the Coronary Drug Project. New England Journal of Medicine 303: 1038-41.
10. Fitch, K., K. Iwasaki, and, B. Pyenson,. 2008. Value-Based Insurance Designs for Diabetes Drug Therapy: Actuarial and Implementation Considerations. New York: Milliman.
11. Gellad, W. F., J. Grenard, and, E. A. McGlynn,. 2009. A Review of Barriers to Medication Adherence: A Framework for Driving Policy Options. Santa Monica, CA: The RAND Corporation.
12. Gilmer, T. P., P. J. O'Connor, W. A. Rush, A. L. Crain, R. R. Whitebird, A. M. Hanson, and, L. I. Solberg,. 2005. " Predictors of Health Care Costs in Adults with Diabetes. Diabetes Care 28: 59-64. (Pubitemid 40095783)
13. Golan, L., J. D. Birkmeyer, and, H. G. Welch,. 1999. " The Cost-Effectiveness of Treating all Patients with Type 2 Diabetes with Angiotensin-Converting Enzyme Inhibitors. Annals of Internal Medicine 131: 660-7. (Pubitemid 29517951)
14. Granger, B. B., K. Swedberg, I. Ekman, C. B. Granger, B. Olofsson, J. V. McMurray, S. Yusuf, E. L. Michelson, and, M. A. Pfeffer,. 2005. " Adherence to Candesartan and Placebo and Outcomes in Chronic Heart Failure in the CHARM Programme: Double-Blind, Randomised, Controlled Clinical Trial. The Lancet 366: 2005-11.
15. Hepke, K. L., M. T. Martus, and, D. A. Share,. 2004. " Costs and Utilization Associated with Pharmaceutical Adherence in a Diabetic Population. American Journal of Managed Care 10: 144-51. (Pubitemid 38332389)
16. Herbert, P., L. S. Geiss, E. F. Tierney, M. M. Engelgau, B. P. Yawn, and, A. M. McBean,. 1999. " Identifying Persons with Diabetes Using Medicare Claims. American Journal of Medical Quality 14 (6): 270-7.
17. Horwitz, R. J., and, S. M. Horwitz,. 1993. " Adherence to Treatment and Health Outcomes. Archives of Internal Medicine 153: 1863-8. (Pubitemid 23329840)
18. Kamari, Y., R. Bitzur, H. Cohen, A. Shais, and, D. Harats,. 2009. " Should All Diabetic Patients Be Treated with a Statin? Diabetes Care 32 (2, suppl 2): S378-83.
19. LaRosa, J. C., 2000. " Poor Compliance: The Hidden Risk Factor. Current Atherosclerosis Reports 2: 1-4.
20. Nicholson, S., 2006. " The Effect of Cost Sharing on Employees with Diabetes. The American Journal of Managed Care 12 (Special Issue): SP20-6. (Pubitemid 46053392)
21. Odegard, P. S., and, K. Capoccia,. 2007. " Medication Taking and Diabetes: A Systematic Review of the Literature. Diabetes Education 33: 1014-29; discussion 1030-1031.
22. Rosen, A. B., M. B. Hamel, M. C. Weinstein, D. M. Cutler, A. M. Fendrick, and, S. Vijan,. 2005. " Cost-Effectiveness of Full Medicare Coverage of Angiotensin-Converting Enzyme Inhibitors for Beneficiaries with Diabetes. Annals of Internal Medicine 143: 89-99.
23. Salas, M., D. Hughes, A. Zuluga, K. Vardeva, and, M. Lebmeier,. 2009. " Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature. Value in Health 12 (6): 915-22.
24. Saydah, S. H., L. S. Geiss, E. Tierney, S. M. Benjamin, M. Engelgau, and, F. Brancati,. 2004. " Review of the Performance of Methods to Identify Diabetes Cases among Vital Statistics. Annals of Epidemiology 14: 507-16. (Pubitemid 39061162)
25. Simpson, S. H., D. T. Eurich, S. R. Majumdar, R. S. Padwal, R. T. Tsuyuki, J. Varney, and, J. A. Johnson,. 2006. " A Meta-Analysis of the Association between Adherence to Drug Therapy and Mortality. British Medical Journal 333: 15-8. (Pubitemid 44406838)
26. Sokol, M. C., K. A. McGuigan, R. R. Verbrugge, and, R. S. Epstein,. 2005. " Impact of Medication Adherence on Hospitalization Risk and Healthcare Cost. Medical Care 43: 521-30. (Pubitemid 40847288)
27. Spaulding, J. G., A. M. Fendrick, W. H. Herman, J. G. Stevenson, D. G. Smith, M. E. Chernew, D. M. Parsons, K. Bruhnsen, and, A. B. Rosen,. 2009. " A Controlled Trial of Value-Based Insurance Design- The MHealthy: Focus on Diabetes (FOD) Trial. Implementation Science 4: 19.
28. Stuart, B., L. Simoni-Wastila, L. Zhao, J. Lloyd, and, J. Doshi,. 2009. " Increased Persistency in Medication Use by U.S. Medicare Beneficiaries with Diabetes Is Associated with Lower Hospitalization Rates and Cost Savings. Diabetes Care 32 (4): 647-9.
29. U.S. Congressional Budget Office. 2002. Issues in Designing a Prescription Drug Benefit for Medicare. Washington, DC: U.S. Government Printing Office.
30. U.S. Department of Labor, Bureau of Labor Statistics. 2009. "Consumer Price Index: All Urban Consumers" [accessed on June 15, 2009]. Available at http://www.bls.gov/cpi
31. Vink, N. M., O. H. Klungel, R. P. Stolk, and, P. Denig,. 2009. " Comparison of Various Measures for Assessing Medication Refill Adherence Using Prescription Data. Pharmacoepidemiology and Drug Safety 18: 159-65.