Comparison of various measures for assessing medication refill adherence using prescription data

Pharmacoepidemiology and Drug Safety

Volumn 18, Issue 2, 2009, Pages 159-165

  Vink, N M ^a   Klungel, O H ^b   Stolk, R P ^a   Denig, P ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Administrative data; Diabetes mellitus type 2; Drug utilization; Patient compliance; Primary health care

Indexed keywords

ACARBOSE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BIGUANIDE DERIVATIVE; BILE ACID SEQUESTRANT; CALCIUM ANTAGONIST; CHOLESTEROL; DIURETIC AGENT; FIBRIC ACID DERIVATIVE; GLITAZONE DERIVATIVE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; NICOTINIC ACID DERIVATIVE; ORAL ANTIDIABETIC AGENT; SULFONYLUREA DERIVATIVE; ANTIDIABETIC AGENT;

ACCURACY; AGED; AREA UNDER THE CURVE; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE DURATION; DYSLIPIDEMIA; ELECTRONIC MEDICAL RECORD; FEMALE; HUMAN; HYPERTENSION; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PATIENT COMPLIANCE; PRESCRIPTION; PRIORITY JOURNAL; ROC CURVE; SYSTOLIC BLOOD PRESSURE; COMPARATIVE STUDY; DRUG USE; NETHERLANDS; STATISTICS;

ANTIHYPERTENSIVE AGENTS; ANTILIPEMIC AGENTS; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; DRUG PRESCRIPTIONS; DRUG UTILIZATION REVIEW; HUMANS; HYPOGLYCEMIC AGENTS; NETHERLANDS; PATIENT COMPLIANCE;

EID: 62649084257     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.1698     Document Type: Article

References (14)

1. Pladevall M, Williams LK, Potts LA, et al. Clinical outcomes and adherence to medications measured by claims data in patients with diabetes. Diabetes Care 2004; 27: 2800-2805.
2. Sabate E (ed). Adherence to Long-Term Therapies. Chapter 10 Diabetes, pages 71-85. WHO: Geneva, Switzerland, 2003.
3. DiMatteo MR, Giordani PJ, Lepper HS, et al. Patient adherence and medical treatment outcomes: a meta-analysis. Med Care 2002; 40: 794-811.
4. Ho PM, Rumsfeld JS, Masoudi FA, et al. Effect of medication non-adherence on hospitalization and mortality among patients with diabetes mellitus. Arch Intern Med 2006; 166: 1836-1841.
5. Andrade SE, Kahler KH, Frech F, et al. Methods for evaluation of medication adherence and persistence using automated databases. Pharmacoepidemiol Drug Saf 2006; 15: 565-574.
6. Sikka R, Xia F, Aubert RE. Estimating medication persistency using administrative claims data. Am J Manag Care 2005; 11: 449-457.
7. Steiner JF, Prochazka AV. The assessment of refill compliance using pharmacy records: methods, validity, and applications. J Clin Epidemiol 1997; 50: 105-116.
8. Caetano PA, Lam JM, Morgan SG. Toward a standard definition and measurement of persistence with drug therapy: examples from research on statin and antihypertensive utilization. Clin Ther 2006; 28: 1411-1424.
9. Hess LM, Raebel MA, Conner DA, et al. Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures. Ann Pharmacother 2006; 40: 1280-1288.
10. Van Wijk BLG, Klungel OH, Heerdink ER, et al. Refill persistence with chronic medication assessed from a pharmacy database was influenced by method of calculation. J Clin Epidemiol 2006; 59: 11-17.
11. Hudson M, Rahme E, Richard H, et al. Comparison of measures of medication persistency using a prescription drug database. Am Heart J 2007; 153: 59-65.
12. Voorham J, Haaijer-Ruskamp FM, Stolk RP, et al. Influence of elevated cardiometabolic risk factor levels on treatment changes in type 2 diabetes. Diabetes Care 2008; 31: 501-503.
13. Dik E. Dutch Institute for Rational Drug Use (DGV). In Handboek Werken met cijfers in het FTO [Handbook working with prescription data]. DGV; 2006, Chapter 18, M. Nelissen-VancKen (ed.). Compliance, Utrecht, 18.6-L 18.7. Dutch. Accessed at http://www.medicijngebruik.nl August 11, 2008.
14. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 1983; 148: 839-843.