A study of the anti-diabetic effects of Urena lobata and Sphenostylis stenocarpa in streptozotocin-induced diabetic rats

European Journal of Scientific Research

Volumn 43, Issue 1, 2010, Pages 6-14

  Onoagbe, I O ^a   Negbenebor, E O ^a   Ogbeide, V O ^a   Dawha, I H ^b   Attah, V ^b   Lau, H U ^b   Omonkhua, A A ^c  

^a UNIVERSITY OF BENIN   (Nigeria)

^b UNIVERSITY OF MAIDUGURI   (Nigeria)

^c ADEKUNLE AJASIN UNIVERSITY   (Nigeria)

Author keywords

Anti diabetic plants; Sphenostylis stenocarpa; Streptozotocin diabetic rats; Urena lobata

Indexed keywords

EID: 79960088237     PISSN: 1450216X     EISSN: 1450202X     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Akhtar, M. S., Khan, O. M. and Khaliq, T. (1984). Effect of Prostrata fumaria parviflora in normoglycaemic and Alloxan treated hyperglycaemic rabbits. Planta. Med. 50: 138-142. (Pubitemid 14064507)
2. Ali, L., Azad-Khan, A. K., Hassan, Z., Mosihuzzaman, M., Nahar, N., Nasreen, T., Nur-e-alam, M. and Rokaya, B. (1995). Characterization of the hypoglycaemic effects of Trigonella foenum graecum seed. Planta. Med. 61: 358-360.
3. Arvill A, and Bodin L (1995). Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr. 61:585-9.
4. Association of Official Analytical Chemists (A.O.A.C.) (1990). Official Methods of Analysis. 15th Edition. Washington D.C.
5. Awika J. M. and Rooney L. W. (2004). Sorghum phytochemicals and their potential impact on human health Phytochemistry. 65(9): 1199-1221. (Pubitemid 38746667)
6. David, E. M. (2001). New drug target for Type 2 diabetes and the metabolic syndrome. Nature. 44:821-826.
7. Enyikwola, O. and Onoagbe, I. O. (1992). Hypoglycaemic effect of Mangifera indica in albino rats. Annals of Borno. 8/9: 150-154.
8. Enyikwola, O. and Tshimba, N. (1996). Hypoglycaemic properties of the aqueous extract of Bidena biternata (LOUR) in normal and streptozotocin-induced diabetic rats. West African Journal of Biological Sciences. 5: 17-24.
9. Francis, G., Kerem, Z., Makkar, H. P. S. and Beckerm K. (2002). The biological action of saponins in animal systems: a reviewBritish Journal of Nutrition (2002), 88, 587-605 (Pubitemid 36082888)
10. Grover, J K., Yadav, S. and Vats, V. (2002). Medicinal plants of India with anti-diabetic potential. J. Ethnopharm. 81(1): 81-100. (Pubitemid 34518472)
11. Harborne, J. B. (1973). Phytochemical Methods. A Guide to Modern Techniques of Plant Analysis. 2nd edition. Chapman and Hall, London. Pp 4-26,140-149.
12. Harris, M. I., Flegal, K. M. and Cowie, C. C. (1998). Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care. 21:518-524. (Pubitemid 28172927)
13. Howarth, N. C., Saltzman, E.and Roberts, S. B. (2001). Dietary fiber and weight regulation. Nutr Rev. 59(5):129-139. (Pubitemid 32494625)
14. Ivorra, M. D., Paya, M. and Viller, A. (1988). Hypoglycaemic and insulin release effects of termentic acid: A new hypoglycaemic natural product. Planta. Med. 54: 282-286.
15. Ji, S. K., Jung, B. J., Chang, W. C. and Sei, C. K. (2006). Hypoglycemic and Antihyperlipidemic Effect of Four Korean Medicinal Plants in Alloxan Induced Diabetic Rats. American Journal of Biochemistry and Biotechnology 2 (4): 154-160.
16. Junod, A., Lambert, A. E., Stauffacher, W. and Renold, A. E. (1969). Diabetogenic action of streptozotocin: Relationship of dose to metabolic response. J. Clin. Invest. 48: 2129-2139.
17. Kako, M., Miura, T., Nishiyama, Y, Ichimaru, M., Moriyamu, M. and Kato, A. (1996). Hypoglycaemic effects of the rhizomes of Polygala senega in normal and diabetic mice and its component, the tritepenoid glycoside senegin-II. Planta. Med. 62: 440-443. (Pubitemid 26370338)
18. King, H., Aubert, R. E. and Herman, W. H. (1998). Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care. 21, 1414-1431. (Pubitemid 28405191)
19. Kobayashi, Y., Suzuki, M., Satsu, H., Arai, S., Hara, Y., Suzuki, K., Miyamoto, Y. and Shimizu, M. (2000). Green Tea Polyphenols Inhibit the Sodium-dependent Glucose Transporter of Intestinal Epithelial Cells by a Competitive Mechanism. J. Agric. Food Chem. 48: 5618-5623.
20. Krupp, M. A., Chalton, M. J. And Werdeger, D. (1985). Current medical diagnosis and treatment. California. Lange publications.
21. Lambert, M. and Neish, A. C. (1950). Rapid method of estimation of glycerol in fermentation solution. Can. J. Res. 28: 472-478-
22. Marriif, H. L., Ali, B.H. and Hassan, K. M. (1995). Some pharmacological studies on Artemisia herba-alba (Asso) in rats and mice. J. Ethnopharm. 49: 51-55. (Pubitemid 26010739)
23. Omonkhua, A. A. and Onoagbe, I. O. (2008). Effects of Irvingia grandifolia, Urena lobata and Carica papaya on the Oxidative Status of Normal Rabbits. The Internet Journal of Nutrition and Wellness. 6: 2.
24. Onoagbe, I. O. and Esekheigbe, A. (1999). Studies of the anti-diabetic properties of Uvaria chamae in Streptozotocin-induced diabetic rabbits. Biokemistri. 9: 17-22.
25. Onoagbe, I. O., Attah, V., Luther, M. M. and Esekheigbe, A. (1999a). Hypoglycemic and Anti-Diabetic Effects of Morinda lucida and Tetracera alnifora in Normal and Streptozotocin-Induced Diabetic Rats. West African Journal of Biological Sciences, 9: 1-8.
26. Onoagbe, I. O., Ebhota, A. O., Udegbe, H. C., Omondia, M., Edeni, D. and Ebengho, S. O. (1999b). Assessment of some Medicinal Plants for Hypoglycemic Activities in Rats and Rabbits. Biosci. Res. Commun. 11: 159-163.
27. Onoagbe, I. O., Esekheigbe, A., Ebengho, S. O. and Likibe, C. (1999c). Effect of Strophanthus hispidus and Triumfetta rhomboidea on blood glucose, total lipid and ketone bodies concentrations in normal and streptozotocin- induced diabetic rabbits. West African Journal of Biological Sciences. 11: 97-105.
28. Onoagbe, I. O., Lau, H. U., Esekhiegbe, A., Dawha, I. M. and Salami, C. O. (1999d). Effect of Irvingia grandifolia and Spondias mombin on Blood Glucose and Triglyceride Concentrations in Streptozotocin-Induced Diabetic Rats. Biokemistri. 9(1): 17-22.
29. Roman-Ramos, R., Flores-Saenz. J. L. and Alarcon-Auilar, F. J. (1995). Anti-hyperglycaemic effects of some edible plants. J. Ethnopharm. 48: 25-32.
30. Sharma, S., Chaturvedi, M., Edwin, E., Shukla, S. and Sagrawat, H. (2007). Evaluation of the phytochemicals and antidiabetic activity of Ficus bengalensis. Int. J. Diab. Dev. Ctries. 27(2): 56-59.
31. Sofowora, A. (1993). Medicinal Plants. In: Medicinal plant and traditional medicine in Africa (2nd Ed). Ibadan University Press, Ibadan. Pp. 6-8.
32. Subramoniam, A., Pushpangadan, P., Rajasekharan, S., Evans, D. A. Latha, P. G. and Valsaraj, R. (1996). Effects of Artemisia pallens Wall on blood glucose levels in normal and Alloxaninduced diabetic rats. J. Ethnopharm. 50: 13-17. (Pubitemid 26028891)
33. Tahz, S. A., and Raza, H. (1996). Protection by epicoprostanol against hyperglycaemia and insulitis in normal and diabetic rats. J. Ethnopharm. 50: 85-90.
34. Trease, G. E. and Evans, W. C. (1996). A Textbook of Pharmacognosy. 14th Ed. Bailliere Tindall Ltd.London.
35. Trinder, P. (1969). Determination of blood glucose using 4-aminophenazone as oxygen acceptor. J. Clin. Path. 22: 246.
36. Vedavanam, K., Srijayanta, S., O'Reilly, J., Raman, A. and Wiseman, H. (1999) Antioxidant action and potential antidiabetic properties of an isoflavonoid-containing soyabean phytochemical extract (SPE). Phytother Res. 13(7):601-608. (Pubitemid 29520939)
37. World Health Organization (WHO) (1999). Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus. Department of Non-communicable Disease SurveillanceGeneva.
38. Yuan, Z., He, P., Cui, J. and Takeuchi, H. (1998). Hypoglycaemic Effect of Water-Soluble Polysaccharide from Auricularia aurricula-judae Quel. on Genetic Diabetic KK-ay Mice. Bioscience, Biotech. Biochem. 62(10): 1898-1903. (Pubitemid 128473752)
39. Zlatkis, A., Zak, B. and Boyle, G. J. (1953). A new method for the direct determination of serum cholesterol. J. Lab. Clin. Med. 41: 486.