Stroke: Do statins improve outcomes after acute ischemic stroke?

Nature Reviews Neurology

Volumn 7, Issue 7, 2011, Pages 364-365

  Willey, Joshua Z ^a   Elkind, Mitchell S V ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ACUTE ISCHEMIC STROKE; ARTICLE; ATHEROSCLEROSIS; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CONVALESCENCE; DISEASE DURATION; DRUG EFFICACY; DRUG TOLERABILITY; HUMAN; HYPERLIPIDEMIA; MORTALITY; NEUROPROTECTION; ONSET AGE; PATIENT SAFETY; PRIORITY JOURNAL; RECURRENT DISEASE; TREATMENT OUTCOME;

HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; ISCHEMIA; STROKE; TREATMENT OUTCOME;

EID: 79960086405     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/nrneurol.2011.92     Document Type: Article

References (10)

1. Lloyd-Jones, D. et al. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009, 480-486 (2009
2. Wardlaw, J. M., Murray, V., Berge, E. & Del Zoppo, G. J. Thrombolysis for acute ischaemic stroke. Cochrane Database of Systematic Reviews, Issue 4. Art. No.: CD000213. doi:10.1002/14651858.CD000213.pub2 (2009
3. Willey, J. Z. & Elkind, M. S. 3-Hydroxy-3- methylglutaryl-coenzyme A reductase inhibitors in the treatment of central nervous system diseases. Arch. Neurol. 67, 1062-1067 (2010
4. Biffi, A. et al. Statin treatment and functional outcome after ischemic stroke: case-control and meta-analysis. Stroke 42, 1314-1319 (2011
5. Amarenco, P. et al. High-dose atorvastatin after stroke or transient ischemic attack. N. Engl. J. Med. 355, 549-559 (2006 (Pubitemid 44202151)
6. Westover, M. B., Bianchi, M. T., Eckman, M. H. & Greenberg, S. M. Statin use following intracerebral hemorrhage: a decision analysis. Arch. Neurol. 68, 573-579 (2011
7. Meier, N. et al. Prior statin use, intracranial hemorrhage, and outcome after intra-arterial thrombolysis for acute ischemic stroke. Stroke 40, 1729-1737 (2009
8. Miedema, I., Uyttenboogaart, M., Koopman, K., De Keyser, J. & Luijckx, G. J. Statin use and functional outcome after tissue plasminogen activator treatment in acute ischaemic stroke. Cerebrovasc. Dis. 29, 263-267 (2010
9. Prinz, V. et al. Intravenous rosuvastatin for acute stroke treatment: an animal study. Stroke 39, 433-438 (2008 (Pubitemid 351619468)
10. Elkind, M. S. et al. High-dose lovastatin for acute ischemic stroke: results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART). Cerebrovasc. Dis. 28, 266-275 (2009