Role of neutrophil to lymphocyte ratio as a prognostic indicator for epithelial ovarian cancer

Journal of the Medical Association of Thailand

Volumn 94, Issue 7, 2011, Pages 871-877

  Thavaramara, Thaovalai ^a   Phaloprakarn, Chadakarn ^a   Tangjitgamol, Siriwan ^a   Manusirivithaya, Sumonmal ^a  

^a NAVAMINDRADHIRAJ UNIVERSITY   (Thailand)

Author keywords

Epithelial ovarian cancer; Neutrophil to lymphocyte ratio; Prognostic indicator; Survival

Indexed keywords

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; EPITHELIAL OVARY CANCER; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; NEUTROPHIL COUNT; NEUTROPHIL LYMPHOCYTE RATIO; OUTCOME ASSESSMENT; OVARY CANCER; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PROGNOSIS;

ADULT; AGED; CARCINOMA; FEMALE; GYNECOLOGIC SURGICAL PROCEDURES; HOSPITALS, TEACHING; HUMANS; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; LYMPHOCYTES; MIDDLE AGED; NEOPLASM STAGING; NEOPLASMS, GLANDULAR AND EPITHELIAL; NEUTROPHILS; OVARIAN NEOPLASMS; PREDICTIVE VALUE OF TESTS; PREOPERATIVE CARE; PROGNOSIS; SURVIVAL ANALYSIS; THAILAND; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 79960053304     PISSN: 01252208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, et al. Cancer statistics, 2008. CA Cancer J Clin 2008; 58: 71-96.
2. Thavaramara T, Tangjitgamol S, Manusirivithaya S, Leelahakorn S. Oral etoposide for refractory or recurrent epithelial ovarian cancer. J Med Assoc Thai 2009; 92: 1397-1405.
3. Mei L, Chen H, Wei DM, Fang F, Liu GJ, Xie HY, et al. Maintenance chemotherapy for ovarian cancer. Cochrane Database Syst Rev 2010; (9): CD007414.
4. Bristow RE, Tomacruz RS, Armstrong DK, Trimble EL, Montz FJ. Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a metaanalysis. J Clin Oncol 2002; 20: 1248-1259.
5. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001; 357: 539-545.
6. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002; 420: 860-867.
7. Brower V. Feeding the flame: new research adds to role of inflammation in cancer development. J Natl Cancer Inst 2005; 97: 251-253.
8. Jackson JR, Seed MP, Kircher CH, Willoughby DA, Winkler JD. The codependence of angiogenesis and chronic inflammation. FASEB J 1997; 11: 457-465.
9. Jaiswal M, LaRusso NF, Burgart LJ, Gores GJ. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res 2000; 60: 184-190.
10. McMillan DC, Canna K, McArdle CS. Systemic inflammatory response predicts survival following curative resection of colorectal cancer. Br J Surg 2003; 90: 215-219.
11. Gunter MJ, Stolzenberg-Solomon R, Cross AJ, Leitzmann MF, Weinstein S, Wood RJ, et al. A prospective study of serum C-reactive protein and colorectal cancer risk in men. Cancer Res 2006; 66: 2483-2487.
12. Walsh SR, Cook EJ, Goulder F, Justin TA, Keeling NJ. Neutrophil-lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol 2005; 91: 181-184.
13. Halazun KJ, Aldoori A, Malik HZ, Al Mukhtar A, Prasad KR, Toogood GJ, et al. Elevated preoperative neutrophil to lymphocyte ratio predicts survival following hepatic resection for colorectal liver metastases. Eur J Surg Oncol 2008; 34: 55-60.
14. Liu H, Liu G, Bao Q, Sun W, Bao H, Bi L, et al. The baseline ratio of neutrophils to lymphocytes is associated with patient prognosis in rectal carcinoma. J Gastrointest Cancer 2010; 41: 116-120.
15. Gomez D, Farid S, Malik HZ, Young AL, Toogood GJ, Lodge JP, et al. Preoperative neutrophil-tolymphocyte ratio as a prognostic predictor after curative resection for hepatocellular carcinoma. World J Surg 2008; 32: 1757-1762.
16. Yamanaka T, Matsumoto S, Teramukai S, Ishiwata R, Nagai Y, Fukushima M. The baseline ratio of neutrophils to lymphocytes is associated with patient prognosis in advanced gastric cancer. Oncology 2007; 73: 215-220.
17. Kim HS, Han KH, Chung HH, Kim JW, Park NH, Song YS, et al. Neutrophil to lymphocyte ratio for preoperative diagnosis of uterine sarcomas: a casematched comparison. Eur J Surg Oncol 2010; 36: 691-698.
18. Cho H, Hur HW, Kim SW, Kim SH, Kim JH, Kim YT, et al. Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment. Cancer Immunol Immunother 2009; 58: 15-23.
19. Swenerton K, Muss HB, Robinson E. Salvage chemotherapy for refractory disease in ovarian cancer. In: Gershenson DM, McGuire WP, editors. Ovarian cancer: controversies in management. New York: Churchill Livingstone; 1998: 169-194.
20. Fondevila C, Metges JP, Fuster J, Grau JJ, Palacin A, Castells A, et al. p53 and VEGF expression are independent predictors of tumour recurrence and survival following curative resection of gastric cancer. Br J Cancer 2004; 90: 206-215.
21. Kusumanto YH, Dam WA, Hospers GA, Meijer C, Mulder NH. Platelets and granulocytes, in particular the neutrophils, form important compartments for circulating vascular endothelial growth factor. Angiogenesis 2003; 6: 283-287.