Bridging the efficacyg-effectiveness gap: A regulator's perspective on addressing variability of drug response

Nature Reviews Drug Discovery

Volumn 10, Issue 7, 2011, Pages 495-506

  Eichler, Hans Georg ^a,b   Abadie, Eric ^a,c   Breckenridge, Alasdair ^d   Flamion, Bruno ^a,e   Gustafsson, Lars L ^f   Leufkens, Hubert ^a,g   Rowland, Malcolm ^h   Schneider, Christian K ^a,i,j   Bloechl Daum, Brigitte ^a,k  

^a EUROPEAN MEDICINES AGENCY   (United Kingdom)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c European Medicines Agency Committee for Medicinal Products for Human Use ^*

^d MEDICINES AND HEALTHCARE PRODUCTS REGULATORY AGENCY   (United Kingdom)

^e Federal Agency for Medicines and Health Products Belgium   (Belgium)

^f KAROLINSKA INSTITUTE   (Sweden)

^g UTRECHT UNIVERSITY   (Netherlands)

^h UNIVERSITY OF MANCHESTER   (United Kingdom)

ⁱ PAUL EHRLICH INSTITUT   (Germany)

^j INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^k MEDICAL UNIVERSITY OF VIENNA   (Austria)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ANTIHYPERTENSIVE AGENT; ANTIINFECTIVE AGENT; ANTIRETROVIRUS AGENT; CERIVASTATIN; CHONDROITIN SULFATE; COCAINE; GEFITINIB; GEMFIBROZIL; HEPARIN; INFLIXIMAB; INSULIN; METHOTREXATE; MIBEFRADIL; NELFINAVIR; ORAL CONTRACEPTIVE AGENT; RIMONABANT; ROFECOXIB; TRASTUZUMAB; TUMOR NECROSIS FACTOR INHIBITOR; VARENICLINE; VIGABATRIN; DRUG;

BREAST CANCER; DRUG APPROVAL; DRUG EFFICACY; DRUG LEGISLATION; DRUG MANUFACTURE; DRUG MARKETING; DRUG RESEARCH; DRUG RESPONSE; DRUG UTILIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERSENSITIVITY REACTION; LICENCE; OBESITY; PATIENT ATTITUDE; PATIENT COMPLIANCE; PHARMACOGENOMICS; PRESCRIPTION; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; ARTICLE; DRUG CONTROL; DRUG THERAPY; ELECTRONIC MEDICAL RECORD; PHARMACOGENETICS; RISK ASSESSMENT; TREATMENT OUTCOME;

DRUG AND NARCOTIC CONTROL; DRUG APPROVAL; DRUG THERAPY; ELECTRONIC HEALTH RECORDS; HUMANS; PATIENT COMPLIANCE; PHARMACEUTICAL PREPARATIONS; PHARMACOGENETICS; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 79960048069     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd3501     Document Type: Review

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