Blocking p75 NTR receptors alters polyinnervationz of neuromuscular synapses during development

Journal of Neuroscience Research

Volumn 89, Issue 9, 2011, Pages 1331-1341

  Garcia, Neus ^a   Tomàs, Marta ^a   Santafe, Manel M ^a   Lanuza, Maria A ^a   Besalduch, Nuria ^a   Tomàs, Josep ^a  

^a UNIVERSITAT ROVIRA I VIRGILI   (Spain)

Author keywords

ACh release; Motor nerve terminals; Neurotrophins; Postnatal synapse elimination; Rat

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; IMMUNOGLOBULIN G ANTIBODY; NEUROTROPHIN RECEPTOR P75; NICOTINIC RECEPTOR;

ACETYLCHOLINE RELEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ELECTROPHYSIOLOGY; ENDPLATE POTENTIAL; IMMUNOHISTOCHEMISTRY; INNERVATION; MALE; MUSCLE CELL; NERVE ENDING; NERVE FIBER; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; RAT; SCHWANN CELL; SKELETAL MUSCLE;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, BLOCKING; AXONS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROMYOGRAPHY; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE, SKELETAL; NEUROMUSCULAR JUNCTION; NEURONAL PLASTICITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, NERVE GROWTH FACTOR;

EID: 79960044899     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22620     Document Type: Article

References (45)

1. Angaut-Petit D, Molgo J, Connold AL, Faille L. 1987. The levator auris longus muscle of the mouse: a convenient preparation for studies of short- and long-term presynaptic effects of drugs or toxins. Neurosci Lett 82: 83-88.
2. Barker PA. 2009. Whither proBDNF? Nat Neurosci 12: 105-106.
3. Bewick GS, Young C, Slater CR. 1996. Spatial relationships of utrophin, dystrophin, beta-dystroglycan and beta-spectrin to acetylcholine receptor clusters during postnatal maturation of the rat neuromuscular junction. J Neurocytol 25: 367-379.
4. Boyd JG, Gordon T. 2001. The neurotrophin receptors, trkB and p75, differentially regulate motor axonal regeneration. J Neurobiol 49: 314-325.
5. Corbit KC, Foster DA, Rosner MR. 1999. Protein kinase C delta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells. Mol Cell Biol 19: 4209-4218.
6. Chandler CE, Parsons LM, Hosang M, Shooter EM. 1984. A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells. J Biol Chem 259: 6882-6889.
7. Domeniconi M, Zampieri N, Spencer T, Hilaire M, Mellado W, Chao MV, Filbin MT. 2005. MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth. Neuron 46: 849-855.
8. Funakoshi H, Belluardo N, Arenas E, Yamamoto Y, Casabona A, Persson H, Ibanez CF. 1995. Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science 268: 1495-1499.
9. Garcia N, Santafe MM, Tomas M, Lanuza MA, Besalduch N, Tomas J. 2009. Neurotrophin-4 couples to locally modulated ACh release at the end of neuromuscular synapse maturation. Neurosci Lett 468: 72-74.
10. Garcia N, Santafe MM, Tomas M, Lanuza MA, Besalduch N, Tomas J. 2010a. Involvement of brain-derived neurotrophic factor (BDNF) in the functional elimination of synaptic contacts at polyinnervated neuromuscular synapses during development. J Neurosci Res 88: 1406-1419.
11. Garcia N, Santafe MM, Tomas M, Lanuza MA, Besalduch N, Tomas J. 2010b. Involvement of neurotrophin-3 (NT-3) in the functional elimination of synaptic contacts during neuromuscular development. Neurosci Lett 473: 141-145.
12. Garcia N, Tomas M, Santafe MM, Besalduch N, Lanuza MA, Tomas J. 2010c. The interaction between tropomyosin-related kinase B receptors and presynaptic muscarinic receptors modulates transmitter release in adult rodent motor nerve terminals. J Neurosci 30: 16514-16522.
13. NTR receptor by high-resolution immunohistochemistry on the adult mouse neuromuscular junction. J Periph Nerv Syst 15: 40-49.
14. Gonzalez M, Ruggiero FP, Chang Q, Shi YJ, Rich MM, Kraner S, Balice-Gordon RJ. 1999. Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions. Neuron 24: 567-583.
15. Heumann R, Korsching S, Bandtlow C, Thoenen H. 1987. Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol 104: 1623-1631.
16. Jansen JK, Fladby T. 1990. The perinatal reorganization of the innervation of skeletal muscle in mammals. Prog Neurobiol 34: 39-90.
17. Kimpinski K, Jelinski S, Mearow K. 1999. The anti-p75 antibody, MC192, and brain-derived neurotrophic factor inhibit nerve growth factor-dependent neurite growth from adult sensory neurons. Neuroscience 93: 253-263.
18. Koliatsos VE, Clatterbuck RE, Winslow JW, Cayouette MH, Price DL. 1993. Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo. Neuron 10: 359-367.
19. Koliatsos VE, Cayouette MH, Berkemeier LR, Clatterbuck RE, Price DL, Rosenthal A. 1994. Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons. Proc Natl Acad Sci U S A 91: 3304-3308.
20. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
21. Lanuza MA, Garcia N, Santafe M, Nelson PG, Fenoll-Brunet MR, Tomas J. 2001. Pertussis toxin-sensitive G-protein and protein kinase C activity are involved in normal synapse elimination in the neonatal rat muscle. J Neurosci Res 63: 330-340.
22. Lanuza MA, Garcia N, Santafe M, Gonzalez CM, Alonso I, Nelson PG, Tomas J. 2002. Pre- and postsynaptic maturation of the neuromuscular junction during neonatal synapse elimination depends on protein kinase C. J Neurosci Res 67: 607-617.
23. Lanuza MA, Besalduch N, Garcia N, Sabate M, Santafe MM, Tomas J. 2007. Plastic-embedded semithin cross-sections as a tool for high-resolution immunofluorescence analysis of the neuromuscular junction molecules: specific cellular location of protease-activated receptor-1. J Neurosci Res 85: 748-756.
24. Lee FS, Chao MV. 2001. Activation of Trk neurotrophin receptors in the absence of neurotrophins. Proc Natl Acad Sci U S A 98: 3555-3560.
25. Matsumoto T, Rauskolb S, Polack M, Klose J, Kolbeck R, Korte M, Barde YA. 2008. Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat Neurosci 11: 131-133.
26. McKay SE, Garner A, Caldero J, Tucker RP, Large T, Oppenheim RW. 1996. The expression of trkB and p75 and the role of BDNF in the developing neuromuscular system of the chick embryo. Development 122: 715-724.
27. McLachlan EM, Martin AR. 1981. Non-linear summation of end-plate potentials in the frog and mouse. J Physiol 311: 307-324.
28. Middleton G, Hamanoue M, Enokido Y, Wyatt S, Pennica D, Jaffray E, Hay RT, Davies AM. 2000. Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons. J Cell Biol 148: 325-332.
29. Nelson PG, Lanuza MA, Jia M, Li MX, Tomas J. 2003. Phosphorylation reactions in activity-dependent synapse modification at the neuromuscular junction during development. J Neurocytol 32: 803-816.
30. Redfern PA. 1970. Neuromuscular transmission in new-born rats. J Physiol 209: 701-709.
31. Reichardt LF. 2006. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 361: 1545-1564.
32. Ribchester RR, Barry JA. 1994. Spatial vs. consumptive competition at polyneuronally innervated neuromuscular junctions. Exp Physiol 79: 465-494.
33. Rodriguez-Tebar A, Dechant G, Barde YA. 1990. Binding of brain-derived neurotrophic factor to the nerve growth factor receptor. Neuron 4: 487-492.
34. Sanes JR, Lichtman JW. 1999. Development of the vertebrate neuromuscular junction. Annu Rev Neurosci 22: 389-442.
35. Santafe MM, Garcia N, Lanuza MA, Uchitel OD, Tomas J. 2001. Calcium channels coupled to neurotransmitter release at dually innervated neuromuscular junctions in the newborn rat. Neuroscience 102: 697-708.
36. Santafe MM, Garcia N, Lanuza MA, Tomas M, Besalduch N, Tomas J. 2009. Presynaptic muscarinic receptors, calcium channels, and protein kinase C modulate the functional disconnection of weak inputs at polyinnervated neonatal neuromuscular synapses. J Neurosci Res 87: 1195-1206.
37. Santafe MM, Salon I, Garcia N, Lanuza MA, Uchitel OD, Tomas J. 2004. Muscarinic autoreceptors related with calcium channels in the strong and weak inputs at polyinnervated developing rat neuromuscular junctions. Neuroscience 123: 61-73.
38. Slater CR. 1982a. Neural influence on the postnatal changes in acetylcholine receptor distribution at nerve-muscle junctions in the mouse. Dev Biol 94: 23-30.
39. Slater CR. 1982b. Postnatal maturation of nerve-muscle junctions in hindlimb muscles of the mouse. Dev Biol 94: 11-22.
40. Steinbach JH. 1981. Neuromuscular junctions and alpha-bungarotoxin-binding sites in denervated and contralateral cat skeletal muscles. J Physiol 313: 513-528.
41. Wang XH, Poo MM. 1997. Potentiation of developing synapses by postsynaptic release of neurotrophin-4. Neuron 19: 825-835.
42. NTR by proBDNF facilitates hippocampal long-term depression. Nat Neurosci 8: 1069-1077.
43. Yamashita T, Tohyama M. 2003. The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci 6: 461-467.
44. Yan Q, Johnson EMJr. 1988. An immunohistochemical study of thenerve growth factor receptor in developing rats. J Neurosci 8: 3481-3498.
45. Yang F, Je HS, Ji Y, Nagappan G, Hempstead B, Lu B. 2009. Pro-BDNF-induced synaptic depression and retraction at developing neuromuscular synapses. J Cell Biol 185: 727-741.