Inhibition of Cu2+-mediated generation of reactive oxygen species by the small heat shock protein αb-crystallin: The relative contributions of the N- and C-terminal domains

Free Radical Biology and Medicine

Volumn 51, Issue 3, 2011, Pages 755-762

  Prabhu, Sankaralingam ^a   Srinivas, Volety ^a   Ramakrishna, Tangirala ^a   Raman, Bakthisaran ^a   Rao, Ch Mohan ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

B crystallin; Copper binding; Free radicals; Redox attenuation; Small angle X ray scattering

Indexed keywords

ALPHA CRYSTALLIN; ASCORBIC ACID; COPPER ION; HYDROXYL RADICAL; REACTIVE OXYGEN METABOLITE; TRYPSIN; COPPER; PEPTIDE FRAGMENT; SMALL HEAT SHOCK PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; FENTON REACTION; HOMEOSTASIS; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; CHEMISTRY; DEGENERATIVE DISEASE; GENETICS; HUMAN; METABOLISM; PROTEIN ENGINEERING; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ALPHA-CRYSTALLIN B CHAIN; COPPER; HEAT-SHOCK PROTEINS, SMALL; HUMANS; NEURODEGENERATIVE DISEASES; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960023569     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.05.021     Document Type: Article

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