Structural basis for the enhanced activity of cyclic antimicrobial peptides: The case of BPC194

Biochimica et Biophysica Acta - Biomembranes

Volumn 1808, Issue 9, 2011, Pages 2197-2205

  Mika, Jacek T ^a,b   Moiset, Gemma ^a,b   Cirac, Anna D ^a,b,c   Feliu, Lidia ^c   Bardají, Eduard ^c   Planas, Marta ^c   Sengupta, Durba ^a,b   Marrink, Siewert J ^a,b   Poolman, Bert ^a,b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UNIVERSITY OF GIRONA   (Spain)

Author keywords

Antimicrobial peptide; Molecular dynamics; Peptide folding; Peptide membrane interaction; Structure function of cyclic peptide

Indexed keywords

CYCLIC(LYSYLLYSYLLEUCYLLYSYLLYSYLPHENYLALANYLLYSYLLYSYLLEUCYLGLUTAMINE); POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; BILAYER MEMBRANE; BIOPHYSICS; MEMBRANE BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

ANTIMICROBIAL CATIONIC PEPTIDES; BIOPHYSICS; CELL MEMBRANE; CIRCULAR DICHROISM; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPIDS; LIPOSOMES; MEMBRANES, ARTIFICIAL; MOLECULAR CONFORMATION; PEPTIDES; PEPTIDES, CYCLIC; PERMEABILITY; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; TIME FACTORS;

EID: 79960015637     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.05.001     Document Type: Article

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