Ent-16β,17-dihydroxy-kauran-19-oic acid, a kaurane diterpene acid from Siegesbeckia pubescens, presents antiplatelet and antithrombotic effects in rats

Phytomedicine

Volumn 18, Issue 10, 2011, Pages 873-878

  Wang, J P ^a   Xu, H X ^b   Wu, Y X ^a   Ye, Y J ^c   Ruan, J L ^a   Xiong, C M ^a   Cai, Y L ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN UNIVERSITY OF TECHNOLOGY   (China)

^c WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Antiplatelet; Antithrombotic; Ent 16 ,17 dihydroxy kauran 19 oic acid; Siegesbeckia pubescens

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTICOAGULANT AGENT; ARACHIDONIC ACID; CYCLIC AMP; ENT 16 BETA,17 DIHYDROXY KAURAN 19 OIC ACID; KAURANE DERIVATIVE; PLANT EXTRACT; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTERIOVENOUS SHUNT; ARTICLE; BLEEDING; CHINESE HERB; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; RADIOIMMUNOASSAY; RAT; SIEGESBECKIA PUBESCENS; THROMBOCYTE AGGREGATION; THROMBOGENESIS; THROMBUS;

6-KETOPROSTAGLANDIN F1 ALPHA; ADENOSINE DIPHOSPHATE; ANIMALS; ASTERACEAE; CORONARY THROMBOSIS; CYCLIC AMP; DITERPENES, KAURANE; EPOPROSTENOL; FEMALE; FIBRINOLYTIC AGENTS; HEMORRHAGE; MALE; MICE; MICE, INBRED ICR; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RATS; RATS, WISTAR; THROMBIN; THROMBOXANE A2; THYROGLOBULIN;

RATTUS; SIEGESBECKIA;

EID: 79959993825     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.01.024     Document Type: Article

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