The Iron-Responsive, GATA-Type transcription factor Cir1 influences mating in cryptococcus neoformans

Molecules and Cells

Volumn 31, Issue 1, 2011, Pages 73-77

  Jung, Won Hee ^b   Kronstad, James W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Chung Ang University   (South Korea)

Author keywords

CIR1; Copper; Cryptococcus neoformans; Iron; Mating

Indexed keywords

COPPER; PROTEIN; PROTEIN CIR1; SEX PHEROMONE; TRANSCRIPTION FACTOR GATA; UNCLASSIFIED DRUG;

ARTICLE; CRYPTOCOCCUS NEOFORMANS; FUNGAL GENE; FUNGUS MUTANT; MATING; NONHUMAN; PROTEIN EXPRESSION; SEXUAL DEVELOPMENT;

COPPER; CRYPTOCOCCUS NEOFORMANS; FUNGAL PROTEINS; GATA TRANSCRIPTION FACTORS; GENES, MATING TYPE, FUNGAL; IRON; MUTAGENESIS, INSERTIONAL; PHENOTYPE; PHEROMONES; TRANSCRIPTION, GENETIC;

FILOBASIDIELLA NEOFORMANS; FUNGI;

EID: 79959983504     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-011-0011-0     Document Type: Article

References (20)

1. Alspaugh, J.A., Perfect, J.R., and Heitman, J. (1997). Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. Genes Dev. 11, 3206-3217. (Pubitemid 27528060)
2. Bicanic, T., and Harrison, T. S. (2004). Cryptococcal meningitis. Br. Med. Bull 72, 99-118. (Pubitemid 40712661)
3. Erke, K.H. (1976). Light microscopy of basidia, basidiospores, and nuclei in spores and hyphae of Filobasidiella neoformans (Cryptococcus neoformans). J. Bacteriol. 128, 445-455.
4. Feldbrugge, M., Kamper, J., Steinberg, G., and Kahmann, R. (2004). Regulation of mating and pathogenic development in Ustilago maydis. Curr. Opin. Microbiol. 7, 666-672. (Pubitemid 39536295)
5. Hassett, R., and Kosman, D.J. (1995). Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae. J. Biol. Chem. 270, 128-134.
6. Hsueh, Y.P., and Heitman, J. (2008). Orchestration of sexual reproduction and virulence by the fungal mating-type locus. Curr. Opin. Microbiol. 11, 517-524.
7. Hull, C.M., Boily, M.J., and Heitman, J. (2005). Sex-specific homeodomain proteins Sxi1alpha and Sxi2a coordinately regulate sexual development in Cryptococcus neoformans. Eukaryot. Cell 4, 526-535. (Pubitemid 40383756)
8. Idnurm, A., Bahn, Y.S., Nielsen, K., Lin, X., Fraser, J.A., and Heitman, J. (2005). Deciphering the model pathogenic fungus Cryptococcus neoformans. Nat. Rev. Microbiol. 3, 753-764. (Pubitemid 41518736)
9. Jung, W.H., Sham, A., White, R., and Kronstad, J.W. (2006). Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans. PLoS Biol. 4, e410.
10. Kent, C.R., Ortiz-Bermudez, P., Giles, S.S., and Hull, C.M. (2008). Formulation of a defined V8 medium for induction of sexual development of Cryptococcus neoformans. Appl. Environ. Microbiol. 74, 6248-6253.
11. Kwon-Chung, K.J., Edman, J.C., and Wickes, B.L. (1992). Genetic association of mating types and virulence in Cryptococcus neoformans. Infect Immun 60, 602-605.
12. Lee, S.C., Ni, M., Li, W., Shertz, C., and Heitman, J. (2010). The evolution of sex: a perspective from the fungal kingdom. Microbiol. Mol. Biol. Rev. 74, 298-340.
13. Lengeler, K.B., Davidson, R.C., D'Souza, C., Harashima, T., Shen, W.C., Wang, P., Pan, X., Waugh, M., and Heitman, J. (2000). Signal transduction cascades regulating fungal development and virulence. Microbiol. Mol. Biol. Rev. 64, 746-785 (Pubitemid 32475930)
14. Ogur, M., St. John, R., and Nagai, S. (1957). Tetrazolium overlay technique for population studies of respiration deficiency in yeast. Science 125, 928-929.
15. Sambrook, J., Fritch, E.F., and Maniatis, T. (1989). Molecular Cloning, a laboratory manual (New York, USA: Cold Spring Harbor Laboratory Press).
16. Stanton, B.C., Giles, S.S., Staudt, M.W., Kruzel, E.K., and Hull, C.M. (2010). Allelic exchange of pheromones and their receptors reprograms sexual identity in Cryptococcus neoformans. PLoS Genet. 6, e1000860.
17. Toffaletti, D.L., Rude, T.H., Johnston, S.A., Durack, D.T., and Perfect, J.R. (1993). Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA. J. Bacteriol. 175, 1405-1411. (Pubitemid 23081817)
18. Wang, P., and Heitman, J. (1999). Signal transduction cascades regulating mating, filamentation, and virulence in Cryptococcus neoformans. Curr. Opin. Microbiol. 2, 358-362. (Pubitemid 29366955)
19. Wang, P., Perfect, J.R., and Heitman, J. (2000). The G-protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans. Mol. Cell. Biol. 20, 352-362. (Pubitemid 30002576)
20. Wickes, B.L., Mayorga, M.E., Edman, U., and Edman, J.C. (1996). Dimorphism and haploid fruiting in Cryptococcus neoformans: association with the alpha-mating type. Proc. Natl. Acad. Sci. USA 93, 7327-7331. (Pubitemid 26243549)