Epitope mapping and structural analysis of the anti-Der p 1 monoclonal antibody: Insight into therapeutic potential

Journal of Molecular Medicine

Volumn 89, Issue 7, 2011, Pages 701-712

  Dai, Yu Chou ^a   Chuang, Woei Jer ^a   Chua, Kaw Yan ^b   Shieh, Chi Chang ^a   Wang, Jiu Yao ^a,c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cysteine protease; Der p 1; House dust mite; Monoclonal antibodies; Protease allergy

Indexed keywords

CYSTEINE PROTEINASE; HOUSE DUST ALLERGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY W108; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTIBODY STRUCTURE; ARTICLE; CONTROLLED STUDY; DERMATOPHAGOIDES PTERONYSSINUS; ENZYME ACTIVITY; EPITOPE MAPPING; FEMALE; HUMAN; HYBRIDOMA; IMMUNOBLOTTING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; TWO DIMENSIONAL ELECTROPHORESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, DERMATOPHAGOIDES; ASTHMA; BINDING SITES, ANTIBODY; DISEASE MODELS, ANIMAL; EPITOPE MAPPING; EPITOPES; FEMALE; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; INFLAMMATION; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEOMICS; RESPIRATORY SYSTEM;

EID: 79959973530     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0744-4     Document Type: Article

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