Interaction of morphine and potassium channel openers on experimental models of pain in mice

Fundamental and Clinical Pharmacology

Volumn 25, Issue 4, 2011, Pages 479-484

  Khanna, Naresh ^a   Malhotra, Rachpal S ^a   Mehta, Ashish K ^a   Garg, Gobind R ^a   Halder, Sumita ^a   Sharma, Krishna K ^a  

^a UNIVERSITY COLLEGE OF MEDICAL SCIENCES   (India)

Author keywords

Antinociception; Formalin test; Morphine; Potassium channel openers; Tail flick test

Indexed keywords

CROMAKALIM; DIAZOXIDE; FORMALDEHYDE; GLIBENCLAMIDE; MINOXIDIL SULFATE; MORPHINE SULFATE; NALOXONE; POTASSIUM CHANNEL STIMULATING AGENT;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG DOSE COMPARISON; DRUG POTENCY; FEMALE; MALE; MOUSE; NONHUMAN; PAIN; PRIORITY JOURNAL; TAIL FLICK TEST;

ANIMALS; CALCIUM CHANNEL AGONISTS; CROMAKALIM; DIAZOXIDE; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FEMALE; GLYBURIDE; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MICE, INBRED STRAINS; MINOXIDIL; MORPHINE; NALOXONE; PAIN; PAIN MEASUREMENT; POTASSIUM CHANNELS;

EID: 79959966879     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2010.00880.x     Document Type: Article

References (29)

1. Herz A., Teschemacher H.J. Activities and sites of antinociceptive action of morphine-like analgesics and kinetics of distribution following intravenous, intracerebral, and intraven-tricular application. Adv. Drug Res. (1971) 6 79-119.
2. Yaksh T.L., Rudy T.A. Analgesia mediated by a direct spinal action of narcotics. Science (1976) 192 1357-1358.
3. Bentley G.A., Newton S.H., Starr J. Evidence for an action of morphine and the enkephalins on sensory nerve endings in the mouse peritoneum. Br. J. Pharmacol. (1981) 73 325-332.
4. Ferreira S.H., Nakamura M. Prostaglandin hyperalgesia: the peripheral analgesic activity of morphine, enkephalins and opioid antagonists. Prostaglandins (1979) 18 191-200.
5. Stein C., Hassan A.H.S., Przewlocki R., Gramsch C., Peter K., Herz A. Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation. Proc. Natl. Acad. Sci. U.S.A. (1990) 87 5935-5939.
6. North R.A. Drug receptors and the inhibition of nerve cells. Br. J. Pharmacol. (1989) 98 13-28.
7. Ocana A.M., Del Pozo E., Barrios M., Robles L.I., Baeyens J.M. An ATP-dependent potassium channel blocker antagonises morphine analgesia. Eur. J. Pharmacol. (1990) 186 377-378.
8. Ocana A.M., Del Pozo E., Barrios M., Baeyens J.M. Subgroups among mu-opioid receptor agonists distinguished by ATP-sensitive K+ channel-acting drugs. Br. J. Pharmacol. (1995) 114 1296-1302.
9. Roane D.S., Boyd N.E. Reduction of food intake and morphine analgesia by central glibenclamide. Pharmacol. Biochem. Behav. (1993) 46 205-207.
10. Wild K.D., Vanderah T., Mosberg H.I., Porreca F. Opioid delta receptor subtypes are associated with different potassium channels. Eur. J. Pharmacol. (1991) 193 135-136.
11. + (GIRK) channels in opioid-induced analgesia. Neurosci. Res. (2000) 38 113-116.
12. Yalcin I., Aksu F. Involvement of potassium channels and nitric oxide in tramadol antinociception. Pharmacol. Biochem. Behav. (2005) 80 69-75.
13. Ocana M., Cendán C.M., Cobos E.J., Entrena J.M., Baeyens J.M. Potassium channels and pain: present realities and future opportunities. Eur. J. Pharmacol. (2004) 500 203-219.
14. Campbell V.C., Welch S.P. The role of minoxidil on endogenous opioid peptides in the spinal cord: a putative co-agonist relationship between K-ATP openers and opioids. Eur. J. Pharmacol. (2001) 417 91-98.
15. Longman S.D., Hamilton T.C. Potassium channel activator drugs: mechanism of action, pharmacological properties, and therapeutic potential. Med. Res. Rev. (1992) 12 73-148.
16. Khalilzadeh O., Anvari M., Khalilzadeh A., Sahebgharani M., Zarrindast M.R. Involvement of amlodipine, diazoxide, and glibenclamide in development of morphine tolerance in mice. Int. J. Neurosci. (2008) 118 503-518.
17. +-channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides. Eur. J. Pharmacol. (1999) 385 119-127.
18. Narita M., Takamori K., Kawashima N. et al. Activation of central ATP-sensitive potassium channels produces the antinociception and spinal noradrenaline turnover-enhancing effect in mice. Psychopharmacology (1993) 113 11-14.
19. Vergoni A.V., Scarano A., Bertolini A. Pinacidil potentiates morphine analgesia. Life Sci. (1992) 50 PL135.
20. Welch S.P., Dunlow L.D. Antinociceptive activity of intrathecally administered potassium channel openers and opioid agonists: a common mechanism of action? J. Pharmacol. Exp. Ther. (1993) 267 390-399.
21. Cook N.S., Quast U. Potassium channel pharmacology, in: Cook N.S. (Ed.), Potassium channels: structure, classification, function and therapeutic potential, Ellis Horwood Limited, Chichester, 1990, pp. 181.
22. Lopes L.S., Pereira S.S., Silva L.L. et al. Antinociceptive effect of topiramate in models of acute pain and diabetic neuropathy in rodents. Life Sci. (2009) 84 105-110.
23. Narita M., Suzuki T., Misawa M. et al. Role of central ATP-sensitive potassium channels in the analgesic effect and spinal noradrenaline turnover-enhancing effect of intracerebroventricularly injected morphine in mice. Brain Res. (1992) 596 209-214.
24. + channel blockers antagonize morphine- but not U-50, 488H induced antinociception. Eur. J. Pharmacol. (1993) 230 203-207.
25. +-channel blockers on antinociception induced by alphaE-adrenoceptor, GABA B and Kappa-opioid receptor agonists. Br. J. Pharmacol. (1993) 110 1049-1054.
26. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animal. Pain (1983) 16 109-110.
27. Shibata M., Ohkubo T., Takahashi H., Inoki R. Modified formalin test: characteristic biphasic pain response. Pain (1989) 38 347-352.
28. D'Amour F.E., Smith D.L. A method for determining loss of pain sensation. J. Pharmacol. Exp. Ther. (1941) 72 74-79.
29. +-channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide. J. Pharmacol. Exp. Ther. (1989) 250 261-270.