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Volumn 26, Issue 3, 2011, Pages 731-736

Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: Is DIM a substitute for I3C?

Author keywords

5,6 benzoflavone; Ah receptors; Diindolylmethane; Indole 3 carbinol; Mammary cancer

Indexed keywords

3 INDOLEMETHANOL; ANTINEOPLASTIC AGENT; AROMATIC HYDROCARBON RECEPTOR; BETA NAPHTHOFLAVONE; DIINDOLYLMETHANE; DIMETHYLBENZ[A]ANTHRACENE; METHYLNITROSOUREA; UNCLASSIFIED DRUG;

EID: 79959958115     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1316     Document Type: Article
Times cited : (22)

References (32)
  • 1
    • 0014290323 scopus 로고
    • Induction of increased benzopyrene hydroxylase activity by flavones and related compounds
    • Wattenberg LW, Page MA and Leong JL: Induction of increased benzopyrene hydroxylase activity by flavones and related compounds. Cancer Res 28: 934-937, 1968.
    • (1968) Cancer Res , vol.28 , pp. 934-937
    • Wattenberg, L.W.1    Page, M.A.2    Leong, J.L.3
  • 2
    • 0017597227 scopus 로고
    • Comparison of β naphthoflavone and 3 methylcholanthrene as inducers of hepatic cytochrome(s) P 448 and aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity
    • Boobis AR, Nebert DW and Felton JS: Comparison of β-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P448 and aryl hydrocarbon(benzo[a]pyrene) hydroxylase activity. Mol Pharmacol 13: 259-268, 1977. (Pubitemid 8076771)
    • (1977) Molecular Pharmacology , vol.13 , Issue.2 , pp. 259-268
    • Boobis, A.R.1    Nebert, D.W.2    Felton, J.S.3
  • 3
    • 0001303308 scopus 로고
    • Inhibition of the carcinogenic action of 7,12-dimethylbenzanthracene by beta-napthoflavone
    • Wattenberg LW and Leong JL: Inhibition of the carcinogenic action of 7,12-dimethylbenzanthracene by beta-napthoflavone. Proc Soc Exp Biol Med 128: 940-943, 1968.
    • (1968) Proc Soc Exp Biol Med , vol.128 , pp. 940-943
    • Wattenberg, L.W.1    Leong, J.L.2
  • 4
    • 0015319044 scopus 로고
    • The effects of two isomeric benzoflavones on aryl hydrocarbon hydroxylase and the toxicity and carcinogenicity of polycyclic hydrocarbons
    • Diamond L, McFall R, Miller J and Gelboin HV: The effects of two isomeric benzoflavones on aryl hydrocarbon hydroxylase and the toxicity and carcinogenicity of polycyclic hydrocarbons. Cancer Res 32: 731-736, 1972.
    • (1972) Cancer Res , vol.32 , pp. 731-736
    • Diamond, L.1    McFall, R.2    Miller, J.3    Gelboin, H.V.4
  • 5
    • 0021287398 scopus 로고
    • 1 carcinogenesis in rainbow trout by flavone and indole compounds
    • Nixon JE, Hendricks JD, Pawlowski NE, Pereira CB, Sinnhuber RO and Bailey GS: Inhibition of aflatoxin Bl carcinogenesis in rainbow trout by flavone and indole compounds. Carcinogenesis 5: 615-619, 1984. (Pubitemid 14108570)
    • (1984) Carcinogenesis , vol.5 , Issue.5 , pp. 615-619
    • Nixon, J.E.1    Hendricks, J.D.2    Pawlowski, N.E.3
  • 6
    • 0029585536 scopus 로고
    • Protection by chlorophyllin and indole-3-carbinol against 2-amino-1-methyl-6-phenylimidazo (4,5-b)pyridine (PhlP) induced DNA adducts and colonic aberrant crypts in the F344 rat
    • Guo D, Schut HA, Davis CD, Synderwine EG, Bailey GS and Dashwood RH: Protection by chlorophyllin and indole-3-carbinol against 2-amino-1-methyl-6- phenylimidazo (4,5-b)pyridine (PhlP) induced DNA adducts and colonic aberrant crypts in the F344 rat. Carcinogenesis 16: 2391-2397, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 2391-2397
    • Guo, D.1    Schut, H.A.2    Davis, C.D.3    Synderwine, E.G.4    Bailey, G.S.5    Dashwood, R.H.6
  • 7
    • 0025317426 scopus 로고
    • Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice
    • Morse MA, La Greca SD, Amin SG and Chung FL: Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice. Cancer Res 50: 2613-2617, 1990. (Pubitemid 20150192)
    • (1990) Cancer Research , vol.50 , Issue.9 , pp. 2613-2617
    • Morse, M.A.1    LaGreca, S.D.2    Amin, S.G.3    Chung, F.-L.4
  • 8
    • 0024587563 scopus 로고
    • Quantitative inter-relationships between aflatoxin B1 carcinogen dose, indole-3-carbinol anti-carcinogen dose, target organ DNA adduction and final tumor response
    • Dashwood RH, Arbogast DN, Fong AT, Pereira C, Hendricks JD and Bailey GS: Quantitative interrelationship between aflatoxin B1 carcinogen dose, indole-3-carbinol anti-carcinogen dose, target organ DNA adduction and final tumor response. Carcinogenesis 1: 175-181, 1989. (Pubitemid 19032102)
    • (1989) Carcinogenesis , vol.10 , Issue.1 , pp. 175-181
    • Dashwood, R.H.1    Arbogast, D.N.2    Fong, A.T.3    Pereira, C.4    Hendricks, J.D.5    Bailey, G.S.6
  • 9
    • 0026785514 scopus 로고
    • Inhibitory effects of the natural products indole-3-carbinol and singrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis
    • Tanaka T, Kojima T, Morishita Y and Mori H: Inhibitory effects of the natural products indole-3-carbinol and singrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Jpn J Cancer Res 83: 835-842, 1992.
    • (1992) Jpn J Cancer Res , vol.83 , pp. 835-842
    • Tanaka, T.1    Kojima, T.2    Morishita, Y.3    Mori, H.4
  • 10
    • 0028876658 scopus 로고
    • Cancer chemoprevention by aliphatic selenocyanates: Effect of chain length on inhibition of mammary tumors and DMBA adducts
    • Ip C, Vadhanavikit S and Ganther H: Cancer chemoprevention by aliphatic selenocyanates: effect of chain length on inhibition of mammary tumors and DMBA adducts. Carcinogenesis 16: 35-38, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 35-38
    • Ip, C.1    Vadhanavikit, S.2    Ganther, H.3
  • 11
    • 0031410995 scopus 로고    scopus 로고
    • The plasticizer benzyl butyl phthalate (BBP) inhibits 7,12-dimethylbenz[a] anthracene (DMBA)-induced rat mammary DNA adduct formation and tumorigenesis
    • Singletary KW, MacDonald C and Wallig M: The plasticizer benzyl butyl phthalate (BBP) inhibits 7,12-dimethylbenz[a] anthracene (DMBA)-induced rat mammary DNA adduct formation and tumorigenesis. Carcinogenesis 18: 1669-1973, 1997.
    • (1997) Carcinogenesis , vol.18 , pp. 1669-1973
    • Singletary, K.W.1    MacDonald, C.2    Wallig, M.3
  • 12
    • 0033199170 scopus 로고    scopus 로고
    • Patterns of DNA adduct formation in liver
    • Izzotti A, Camoirano A, Cartiglia C, et al: Patterns of DNA adduct formation in liver. Cancer Res 59: 4285-4290, 1999.
    • (1999) Cancer Res , vol.59 , pp. 4285-4290
    • Izzotti, A.1    Camoirano, A.2    Cartiglia, C.3
  • 13
    • 0025776365 scopus 로고
    • Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice
    • Bradlow HL, Minchovicz JJ, Telang NT and Osborne MP: Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis 12: 1571-1574, 1991.
    • (1991) Carcinogenesis , vol.12 , pp. 1571-1574
    • Bradlow, H.L.1    Minchovicz, J.J.2    Telang, N.T.3    Osborne, M.P.4
  • 14
    • 0028281779 scopus 로고
    • Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol
    • Kojima T, Tanaka T and Mori H: Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol. Cancer Res 54: 1446-1449, 1994. (Pubitemid 24106404)
    • (1994) Cancer Research , vol.54 , Issue.6 , pp. 1446-1449
    • Kojima, T.1    Tanaka, T.2    Mori, H.3
  • 16
    • 0000317180 scopus 로고    scopus 로고
    • Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?
    • Zhu BT and Conney AH: Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis. Cancer Res 58: 2269-2277, 1998. (Pubitemid 28252677)
    • (1998) Cancer Research , vol.58 , Issue.11 , pp. 2269-2277
    • Zhu, B.T.1    Conney, A.H.2
  • 17
    • 0031715037 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
    • DOI 10.1093/carcin/19.9.1631
    • Chen I, McDougal A, Wang F and Safe S: Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis 19: 1631-1639, 1998. (Pubitemid 28441867)
    • (1998) Carcinogenesis , vol.19 , Issue.9 , pp. 1631-1639
    • Chen, I.1    McDougal, A.2    Wang, F.3    Safe, S.4
  • 18
    • 79959956082 scopus 로고
    • Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: Comparisons with 2,3,7,8- tetrachlorodibnezo-p-dioxin
    • Bjeldanes LF, Kim JY, Grose KR, Bartholomew JC and Bradfield CA: Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibnezo-p-dioxin. Proc Natl Acad Sci USA 88: 2543-2547, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.88 , pp. 2543-2547
    • Bjeldanes, L.F.1    Kim, J.Y.2    Grose, K.R.3    Bartholomew, J.C.4    Bradfield, C.A.5
  • 19
    • 0038418500 scopus 로고    scopus 로고
    • Plant-derived 3,3′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells
    • DOI 10.1074/jbc.M300588200
    • Le HT, Schaldach C, Firestone GL and Bjeldanes LF: Plant-derived 3, 1′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem 278: 21136-21145, 2003. (Pubitemid 36806427)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.23 , pp. 21136-21145
    • Le, H.T.1    Schaldach, C.M.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 20
    • 0029023920 scopus 로고
    • Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol
    • Grubbs CJ, Steele VE and Casebolt T: Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol. Anticancer Res 15: 709-716, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 709-716
    • Grubbs, C.J.1    Steele, V.E.2    Casebolt, T.3
  • 21
    • 0022774562 scopus 로고    scopus 로고
    • 32P-post- labeling test for structurally diverse DNA adducts
    • 32P-post-labeling test for structurally diverse DNA adducts. Carcinogenesis 7: 1543-1551, 1996.
    • (1996) Carcinogenesis , vol.7 , pp. 1543-1551
    • Reddy, M.V.1    Randerath, K.2
  • 22
    • 0028346952 scopus 로고
    • Chemoprevention of carcinogen-DNA adducts and chronic degenerative diseases
    • Izzotti A, D'Agostini F, Bagnasco M, et al: Chemoprevention of carcinogen-DNA adducts and chronic degenerative diseases. Cancer Res 54: 1994S-1998S, 1994.
    • (1994) Cancer Res , vol.54
    • Izzotti, A.1    D'Agostini, F.2    Bagnasco, M.3
  • 23
    • 0022149817 scopus 로고
    • 32P-post-labeling analysis of aromatic carcinogen: DNA adducts
    • 32P-post-labeling analysis of aromatic carcinogen: DNA adducts. Cancer Res 45: 5656-5662, 1985.
    • (1985) Cancer Res , vol.45 , pp. 5656-5662
    • Gupta, R.C.1
  • 24
    • 70349627876 scopus 로고    scopus 로고
    • Induced expression of drug metabolizing enzymes by preventive agents: Role of the antioxidant response element
    • Lubet RA, Yao R, Grubbs CJ, You M and Wang Y: Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element. Chem Biol Interact 182: 22-28, 2009.
    • (2009) Chem Biol Interact , vol.182 , pp. 22-28
    • Lubet, R.A.1    Yao, R.2    Grubbs, C.J.3    You, M.4    Wang, Y.5
  • 25
    • 0000986313 scopus 로고
    • The chi square test for heterogeneity of proportion after adjusting for stratification
    • Armitage P: The chi square test for heterogeneity of proportion after adjusting for stratification. J R Stat Soc B 28: 150-163, 1966.
    • (1966) J R Stat Soc B , vol.28 , pp. 150-163
    • Armitage, P.1
  • 26
    • 0024591163 scopus 로고
    • Absolute stereochemistry of the major 7,12-dimethylbenz[a]anthracene-DNA adducts formed in mouse cells
    • Vericat JA, Cheng SC and Dipple A: Absolute stereochemistry of the major 7,12-dimethylbenz[alpha]anthracene-DNA adducts formed in mouse cells. Carcinogenesis 10: 567-570, 1989. (Pubitemid 19089926)
    • (1989) Carcinogenesis , vol.10 , Issue.3 , pp. 567-570
    • Vericat, J.A.1    Cheng, S.C.2    Dipple, A.3
  • 27
    • 0026668771 scopus 로고
    • Effects of indole-3-carbinol on biotransformation enzymes in the rat: In vivo changes in liver and small intestinal mucosa in comparison with primary rat hepatocyte cultures
    • Wortelboer HM, van der Linden EC, De Kruif CA, et al: Effects of indole-3-carbinol on biotransformation enzymes in the rat: in vivo changes in liver and small intestinal mucosa in comparison with primary rat hepatocyte cultures. Food Chem Toxicol 30: 589-599, 1992.
    • (1992) Food Chem Toxicol , vol.30 , pp. 589-599
    • Wortelboer, H.M.1    Van Der Linden, E.C.2    De Kruif, C.A.3
  • 28
    • 0029959032 scopus 로고    scopus 로고
    • Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells
    • DOI 10.1016/0006-2952(96)00060-3
    • Chen I, Safe S and Bjeldanes L: Indole-3-carbinol and diindolyl-methane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells. Biochem Pharmacol 51: 1069-1076, 1996. (Pubitemid 26104627)
    • (1996) Biochemical Pharmacology , vol.51 , Issue.8 , pp. 1069-1076
    • Chen, I.1    Safe, S.2    Bjeldanes, L.3
  • 29
    • 0344295074 scopus 로고    scopus 로고
    • Metabolic aspects of inhibition by 5,6-benzoflavone on mammary tumorigenesis in the rat
    • Malejka-Giganti D, Benett K, Culp SJ and Beland RA: Metabolic aspects of inhibition by 5,6-benzoflavone on mammary tumorigenesis in the rat. Proc Am Assoc Cancer Res 37: 265, 1996.
    • (1996) Proc Am Assoc Cancer Res , vol.37 , pp. 265
    • Malejka-Giganti, D.1    Benett, K.2    Culp, S.J.3    Beland, R.A.4
  • 30
    • 0025793209 scopus 로고
    • Omeprazole and the induction of human cytochrome P450: A response to concerns about potential adverse effects
    • Parkinson A and Hurwitz A: Omeprazole and the induction of human cytochrome P450: a response to concerns about potential adverse effects. Gastroenterology 100: 1157-1164, 1991.
    • (1991) Gastroenterology , vol.100 , pp. 1157-1164
    • Parkinson, A.1    Hurwitz, A.2
  • 31
    • 0023267279 scopus 로고
    • Enhancement of carcinogenesis by the natural anticarcinogen indole-3-carbinol
    • Bailey GS, Hendericks JD, Shelton DW, Nixon JE and Pawlowski NE: Enhancement of carcinogenesis by the natural anticarcinogen indole-3-carbinol. J Natl Cancer Inst 78: 931-934, 1987. (Pubitemid 17093018)
    • (1987) Journal of the National Cancer Institute , vol.78 , Issue.5 , pp. 931-934
    • Bailey, G.S.1    Hendricks, J.D.2    Shelton, D.W.3
  • 32
    • 69449101827 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands
    • Kawajiri K, Kobayashi Y, Ohtake F, et al: Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc Natl Acad Sci USA 106: 13481-13486, 2009.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13481-13486
    • Kawajiri, K.1    Kobayashi, Y.2    Ohtake, F.3


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