Hormone replacement therapy and women with premature menopause-a cancer survivorship issue

European Journal of Cancer

Volumn 47, Issue 11, 2011, Pages 1623-1632

  King, Judy ^a   Wynne, Catherine Harper ^b   Assersohn, Laura ^c   Jones, Alison ^a  

^a ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

^b MAIDSTONE AND TUNBRIDGE WELLS NHS TRUST   (United Kingdom)

^c ST GEORGE'S UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Cancer; Hormone replacement therapy (HRT); Menopause; Survivorship

Indexed keywords

AROMATASE INHIBITOR; ESTROGEN; ESTROGEN RECEPTOR; FLUOXETINE; GABAPENTIN; GESTAGEN; LUBRICATING AGENT; MEDROXYPROGESTERONE ACETATE; PAROXETINE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SEROTONIN UPTAKE INHIBITOR; TAMOXIFEN; TIBOLONE; VENLAFAXINE;

ADULT; BEHAVIOR THERAPY; BREAST CANCER; CANCER DIAGNOSIS; CANCER INCIDENCE; CANCER RADIOTHERAPY; CANCER RISK; CANCER SURGERY; CANCER SURVIVAL; CANCER THERAPY; COGNITIVE THERAPY; COLORECTAL CANCER; COUNSELING; DEEP VEIN THROMBOSIS; EARLY MENOPAUSE; ENDOMETRIUM CANCER; ENDOMETRIUM SARCOMA; FEMALE; FOLLOW UP; HORMONE SUBSTITUTION; HUMAN; INFERTILITY; INFORMATION; ISCHEMIC HEART DISEASE; LEIOMYOSARCOMA; LUNG EMBOLISM; MEDICAL INFORMATION; MEDICAL PRACTICE; MENOPAUSAL SYNDROME; OVARY CANCER; PHYSICIAN; PREMENOPAUSE; PRIORITY JOURNAL; PROFESSIONAL PRACTICE; QUALITY OF LIFE; REVIEW; SEXUAL DYSFUNCTION; SEXUALITY; SOCIAL ASPECT; STROKE; UNITED KINGDOM; URINE INCONTINENCE; UTERINE CERVIX CANCER; VAGINA ATROPHY; VASOMOTOR DISORDER; WORK;

ADULT; ENDOMETRIAL NEOPLASMS; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; MENOPAUSE, PREMATURE; MIDDLE AGED; NEOPLASMS; OVARIAN NEOPLASMS; QUALITY OF LIFE; RECEPTORS, ESTROGEN; RISK; SURVIVORS;

EID: 79959949594     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2011.04.007     Document Type: Article

References (85)

1. National Cancer Survivorship Initiative (NCSI) vision, Department of Health, Macmillan Cancer Support and NHS Improvement, 19 January 2010. .
2. CancerStats - Cancer Statistics for the UK; .
3. Y.M. Kirova, R.Y. De, and L. Gambotti Second malignancies after breast cancer: the impact of different treatment modalities Br J Cancer 98 5 2008 870 874 (Pubitemid 351341602)
4. R. Ng, N. Better, and M.D. Green Anticancer agents and cardiotoxicity Semin Oncol 33 1 2006 2 14 (Pubitemid 43214484)
5. N. Saquib, S.W. Flatt, and L. Natarajan Weight gain and recovery of pre-cancer weight after breast cancer treatments: evidence from the women's healthy eating and living (WHEL) study Breast Cancer Res Treat 105 2 2007 177 186 (Pubitemid 47366880)
6. J.E. Bower Behavioral symptoms in patients with breast cancer and survivors J Clin Oncol 26 5 2008 768 777 (Pubitemid 351264390)
7. D.S. Dizon Quality of life after breast cancer: survivorship and sexuality Breast J 15 5 2009 500 504
8. L.R. Schover Premature ovarian failure and its consequences: vasomotor symptoms, sexuality, and fertility J Clin Oncol 26 5 2008 753 758 (Pubitemid 351264388)
9. N.E. Avis, S. Crawford, and J. Manuel Psychosocial problems among younger women with breast cancer Psychooncology 13 5 2004 295 308 (Pubitemid 38714192)
10. S. Vujovic, M. Brincat, and T. Erel EMAS position statement: Managing women with premature ovarian failure Maturitas 67 1 2010 91 93
11. R.A. Anderson, A.P. Themmen, A. Al-Qahtani, N.P. Groome, and D.A. Cameron The effects of chemotherapy and long-term gonadotrophin suppression on the ovarian reserve in premenopausal women with breast cancer Hum Reprod 21 10 2006 2583 2592 (Pubitemid 44542149)
12. T. Tominaga, T. Morimoto, Y. Ohasi for the Japan Letrozole Study Group A pivotal double-blind trial in Japan of an aromatase inhibitor Letrozole (third generation) vs. its predecessor fadrozole hydrochloride (second generation) Ann Oncol 11 suppl 2000 25
13. Y.L. Tham, K. Sexton, and H. Weiss The rates of chemotherapy-induced amenorrhea in patients treated with adjuvant doxorubicin and cyclophosphamide followed by a taxane Am J Clin Oncol 30 2 2007 126 132 (Pubitemid 46573245)
14. S.K. Lutchman, S. Muttukrishna, and R.C. Stein Predictors of ovarian reserve in young women with breast cancer Br J Cancer 96 12 2007 1808 1816 (Pubitemid 46912025)
15. K. Oktay, O. Oktem, A. Reh, and L. Vahdat Measuring the impact of chemotherapy on fertility in women with breast cancer J Clin Oncol 24 24 2006 4044 4046 (Pubitemid 46630768)
16. N. Biglia, M. Cozzarella, and F. Cacciari Menopause after breast cancer: a survey on breast cancer survivors Maturitas 45 1 2003 29 38 (Pubitemid 36712889)
17. P. Gupta, D.W. Sturdee, and S.L. Palin Menopausal symptoms in women treated for breast cancer: the prevalence and severity of symptoms and their perceived effects on quality of life Climacteric 9 1 2006 49 58 (Pubitemid 43155683)
18. D.H. Baucom, L.S. Porter, J.S. Kirby, T.M. Gremore, and F.J. Keefe Psychosocial issues confronting young women with breast cancer Breast Dis 23 2005 103 113 (Pubitemid 44308934)
19. K.M. Malinovszky, A. Gould, and E. Foster Quality of life and sexual function after high-dose or conventional chemotherapy for high-risk breast cancer Br J Cancer 95 12 2006 1626 1631 (Pubitemid 44950786)
20. J.M. Pouilles, F. Tremollieres, M. Bonneu, and C. Ribot Influence of early age at menopause on vertebral bone mass J Bone Miner Res 9 3 1994 311 315 (Pubitemid 24080567)
21. D.J. van Der Voort, P.H. van Der Weijer, and R. Barentsen Early menopause: increased fracture risk at older age Osteoporos Int 14 6 2003 525 530 (Pubitemid 36919215)
22. K.D. Crew, H. Greenlee, and J. Capodice Prevalence of joint symptoms in postmenopausal women taking aromatase inhibitors for early-stage breast cancer J Clin Oncol 25 25 2007 3877 3883 (Pubitemid 47477264)
23. C.A. Sklar, A.C. Mertens, and P. Mitby Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study J Natl Cancer Inst 98 13 2006 890 896 (Pubitemid 44018918)
24. M.L. De Bruin, J. Huisbrink, and M. Hauptmann Treatment-related risk factors for premature menopause following Hodgkin lymphoma Blood 111 1 2008 101 108
25. J. Armes, M. Crowe, and L. Colbourne Patients' supportive care needs beyond the end of cancer treatment: a prospective, longitudinal survey J Clin Oncol 27 36 2009 6172 6179
26. P.A. Ganz, G.A. Greendale, L. Petersen, B. Kahn, and J.E. Bower Breast cancer in younger women: reproductive and late health effects of treatment J Clin Oncol 21 22 2003 4184 4193 (Pubitemid 46606187)
27. L.R. Schover Myth-busters: telling the true story of breast cancer survivorship J Natl Cancer Inst 96 24 2004 1800 1801 (Pubitemid 40081309)
28. J.E. Rossouw, G.L. Anderson, and R.L. Prentice Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial JAMA 288 3 2002 321 333 (Pubitemid 34761611)
29. G.L. Anderson, M. Limacher, and A.R. Assaf Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial JAMA 291 14 2004 1701 1712 (Pubitemid 38489892)
30. A.L. Hersh, M.L. Stefanick, and R.S. Stafford National use of postmenopausal hormone therapy: annual trends and response to recent evidence JAMA 291 1 2004 47 53 (Pubitemid 38040534)
31. A. Faber, M.L. Bouvy, and L. Loskamp Dramatic change in prescribing of hormone replacement therapy in The Netherlands after publication of the Million Women Study: a follow-up study Br J Clin Pharmacol 60 6 2005 641 647 (Pubitemid 41705384)
32. MHRA and CHM. MHRA 2007: Drugs Safety Update, Medicines and Healthcare products Regulatory Agency; Volume 1, Issue 2 September 2007.
33. J. Rymer, and E.P. Morris Extracts from 'clinical evidence': menopausal symptoms BMJ 321 7275 2000 1516 1519 (Pubitemid 32011373)
34. P.S. Eriksen, and H. Rasmussen Low-dose 17 beta-estradiol vaginal tablets in the treatment of atrophic vaginitis: a double-blind placebo controlled study Eur J Obstet Gynecol Reprod Biol 44 2 1992 137 144
35. S. Evio, A. Tiitinen, K. Laitinen, O. Ylikorkala, and M.J. Valimaki Effects of alendronate and hormone replacement therapy, alone and in combination, on bone mass and markers of bone turnover in elderly women with osteoporosis J Clin Endocrinol Metab 89 2 2004 626 631 (Pubitemid 38269869)
36. S.L. Hendrix, B.B. Cochrane, and I.E. Nygaard Effects of estrogen with and without progestin on urinary incontinence JAMA 293 8 2005 935 948 (Pubitemid 40271125)
37. S.A. Shumaker, C. Legault, and S.R. Rapp Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial JAMA 289 20 2003 2651 2662 (Pubitemid 37430136)
38. R.T. Chlebowski, L.H. Kuller, and R.L. Prentice Breast cancer after use of estrogen plus progestin in postmenopausal women N Engl J Med 360 6 2009 573 587
39. R.D. Langer Re: estrogen plus progestin therapy and breast cancer in recently postmenopausal women Am J Epidemiol 169 6 2009 784 785
40. R.L. Prentice, R.T. Chlebowski, and M.L. Stefanick Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study Am J Epidemiol 167 12 2008 1407 1415
41. R.L. Prentice, R.T. Chlebowski, and M.L. Stefanick Estrogen plus progestin therapy and breast cancer in recently postmenopausal women Am J Epidemiol 167 10 2008 1207 1216 (Pubitemid 351670642)
42. Collaborative Group on Hormonal Factors in Breast Cancer Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer Lancet 350 9084 1997 1047 1059
43. V. Beral Breast cancer and hormone-replacement therapy in the Million Women Study Lancet 362 9382 2003 419 427 (Pubitemid 36999703)
44. V. Beral, D. Bull, J. Green, and G. Reeves Ovarian cancer and hormone replacement therapy in the Million Women Study Lancet 369 9574 2007 1703 1710 (Pubitemid 46755369)
45. S.M. Harman, E.A. Brinton, and T. Clarkson Is the WHI relevant to HRT started in the perimenopause? Endocrine 24 3 2004 195 202 (Pubitemid 41271149)
46. F. Naftolin, H.S. Taylor, and R. Karas The Women's Health Initiative could not have detected cardioprotective effects of starting hormone therapy during the menopausal transition Fertil Steril 81 6 2004 1498 1501 (Pubitemid 38748989)
47. S.O. Mueller, and K.S. Korach Estrogen receptors and endocrine diseases: lessons from estrogen receptor knockout mice Curr Opin Pharmacol 1 6 2001 613 619 (Pubitemid 33586003)
48. J.F. Couse, J. Lindzey, K. Grandien, J.A. Gustafsson, and K.S. Korach Tissue distribution and quantitative analysis of estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse Endocrinology 138 11 1997 4613 4621 (Pubitemid 27460895)
49. C.J. Fabian, and B.F. Kimler Selective estrogen-receptor modulators for primary prevention of breast cancer J Clin Oncol 23 8 2005 1644 1655 (Pubitemid 46211419)
50. S.A. Joslyn Hormone receptors in breast cancer: racial differences in distribution and survival Breast Cancer Res Treat 73 1 2002 45 59 (Pubitemid 34548165)
51. C.K. Anders, D.S. Hsu, and G. Broadwater Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression J Clin Oncol 26 20 2008 3324 3330
52. A. Goldhirsch, J.N. Ingle, and R.D. Gelber Thresholds for therapies: highlights of the St. Gallen International Expert Consensus on the primary therapy of early breast cancer 2009 Ann Oncol 20 8 2009 1319 1329
53. RCOG and the hormone replacement therapy (HRT) debate.
54. M. Gershanovich, H.A. Chaudri, and D. Campos Letrozole, a new oral aromatase inhibitor: randomised trial comparing 2.5 mg daily, 0.5 mg daily and aminoglutethimide in postmenopausal women with advanced breast cancer. Letrozole International Trial Group (AR/BC3) Ann Oncol 9 6 1998 639 645 (Pubitemid 28318197)
55. A.H. Partridge, S. Gelber, and J. Peppercorn Web-based survey of fertility issues in young women with breast cancer J Clin Oncol 22 20 2004 4174 4183 (Pubitemid 41185188)
56. N.F. Col, J.A. Kim, and R.T. Chlebowski Menopausal hormone therapy after breast cancer: a meta-analysis and critical appraisal of the evidence Breast Cancer Res 7 4 2005 R535 R540
57. L. Holmberg, and H. Anderson HABITS (hormonal replacement therapy after breast cancer - is it safe?), a randomised comparison: trial stopped Lancet 363 9407 2004 453 455 (Pubitemid 38210063)
58. S.E. von, and L.E. Rutqvist Menopausal hormone therapy after breast cancer: the Stockholm randomized trial J Natl Cancer Inst 97 7 2005 533 535 (Pubitemid 40590435)
59. M. Hickey, C.M. Saunders, and B.G. Stuckey Management of menopausal symptoms in patients with breast cancer: an evidence-based approach Lancet Oncol 6 9 2005 687 695 (Pubitemid 41222759)
60. P. Kenemans, N.J. Bundred, and J.M. Foidart Safety and efficacy of tibolone in breast-cancer patients with vasomotor symptoms: a double-blind, randomised, non-inferiority trial Lancet Oncol 10 2 2009 135 146
61. A. Kendall, M. Dowsett, E. Folkerd, and I. Smith Caution: vaginal estradiol appears to be contraindicated in postmenopausal women on adjuvant aromatase inhibitors Ann Oncol 17 4 2006 584 587
62. D.C. Smith, R. Prentice, D.J. Thompson, and W.L. Herrmann Association of exogenous estrogen and endometrial carcinoma N Engl J Med 293 23 1975 1164 1167
63. D. Grady, T. Gebretsadik, K. Kerlikowske, V. Ernster, and D. Petitti Hormone replacement therapy and endometrial cancer risk: a meta-analysis Obstet Gynecol 85 2 1995 304 313
64. I. Persson, H.O. Adami, and L. Bergkvist Risk of endometrial cancer after treatment with oestrogens alone or in conjunction with progestogens: results of a prospective study BMJ 298 6667 1989 147 151 (Pubitemid 19039672)
65. R.R. Barakat, B.N. Bundy, N.M. Spirtos, J. Bell, and R.S. Mannel Randomized double-blind trial of estrogen replacement therapy versus placebo in stage I or II endometrial cancer: a Gynecologic Oncology Group Study J Clin Oncol 24 4 2006 587 592 (Pubitemid 46630420)
66. M.C. Chu, G. Mor, and C. Lim Low-grade endometrial stromal sarcoma: hormonal aspects Gynecol Oncol 90 1 2003 170 176 (Pubitemid 37338093)
67. L. Hinds, and J. Price Menopause, hormone replacement and gynaecological cancers Menopause Int 16 2 2010 89 93
68. D. Goswami, and G.S. Conway Premature ovarian failure Hum Reprod Update 11 4 2005 391 410 (Pubitemid 40895467)
69. P. Fobair, S.L. Stewart, and S. Chang Body image and sexual problems in young women with breast cancer Psychooncology 15 7 2006 579 594 (Pubitemid 44102744)
70. E. Beckjord, and B.E. Campas Sexual quality of life in women with newly diagnosed breast cancer J Psychosoc Oncol 25 2 2007 19 36 (Pubitemid 47038131)
71. S.R. Wimberly, C.S. Carver, J.P. Laurenceau, S.D. Harris, and M.H. Antoni Perceived partner reactions to diagnosis and treatment of breast cancer: impact on psychosocial and psychosexual adjustment J Consult Clin Psychol 73 2 2005 300 311 (Pubitemid 40446386)
72. C.L. Loprinzi, S. Abu-Ghazaleh, and J.A. Sloan Phase III randomized double-blind study to evaluate the efficacy of a polycarbophil-based vaginal moisturizer in women with breast cancer J Clin Oncol 15 3 1997 969 973 (Pubitemid 27106279)
73. E. Weisberg, R. Ayton, and G. Darling Endometrial and vaginal effects of low-dose estradiol delivered by vaginal ring or vaginal tablet Climacteric 8 1 2005 83 92 (Pubitemid 40675125)
74. L. Bordeleau, K. Pritchard, P. Goodwin, and C. Loprinzi Therapeutic options for the management of hot flashes in breast cancer survivors: an evidence-based review Clin Ther 29 2 2007 230 241 (Pubitemid 46661858)
75. Y. Jin, Z. Desta, and V. Stearns CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment J Natl Cancer Inst 97 1 2005 30 39
76. V. Stearns, M.D. Johnson, and J.M. Rae Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine J Natl Cancer Inst 95 23 2003 1758 1764 (Pubitemid 38008898)
77. J.M. Hoskins, L.A. Carey, and H.L. McLeod CYP2D6 and tamoxifen: DNA matters in breast cancer Nat Rev Cancer 9 8 2009 576 586
78. M.P. Goetz, S.K. Knox, and V.J. Suman The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen Breast Cancer Res Treat 101 1 2007 113 121 (Pubitemid 47555336)
79. G. Deng, A. Vickers, and S. Yeung Randomized, controlled trial of acupuncture for the treatment of hot flashes in breast cancer patients J Clin Oncol 25 35 2007 5584 5590
80. D.F. McMichael-Phillips, C. Harding, and M. Morton Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast Am J Clin Nutr 68 6 Suppl 1998 1431S 1435S
81. D.F. McMichael-Phillips, C. Harding, and M. Morton Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast Am J Clin Nutr 68S 1998 S431 S436
82. V. Mattioli, R. Montanaro, and F. Romito The Italian response to cancer survivorship research and practice: developing an evidence base for reform J Cancer Surviv 4 3 2010 284 289
83. F. Berrino, A. Verdecchia, and J.M. Lutz Comparative cancer survival information in Europe Eur J Cancer 45 6 2009 901 908
84. A. Micheli, R. Capocaccia, and C. Martinez Cancer control in Europe: a proposed set of European cancer health indicators Eur J Public Health 13 3 Suppl 2003 116 118 (Pubitemid 37158456)
85. Hewitt IOM M. Hewitt, S. Greenfield, E. Stovall, From cancer patient to cancer survivor: lost in transition 2006 The National Academies Press Washington, DC