Gestational dermatosis shortly after implantation associated with parental class II HLA compatibility and maternal immune activation: Preliminary report of a prospective case series

Dermatology

Volumn 222, Issue 3, 2011, Pages 206-211

  Gleicher, Norbert ^a,c   Barad, David H ^a,b  

^a New York and Foundation for Reproductive Medicine   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmunity; Dermatosis of pregnancy; Histocompatibility antigens; Immune activation; Implantation rash; Infertility; Pregnancy; Skin rash

Indexed keywords

CORTICOSTEROID; HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN; PRASTERONE; PREDNISONE;

ACNE VULGARIS; ADULT; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; DIFFERENTIAL DIAGNOSIS; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; EMBRYO TRANSFER; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FIRST TRIMESTER PREGNANCY; FOLLICULITIS; HLA TYPING; HUMAN; IMPETIGO HERPETIFORMIS; INTRAHEPATIC CHOLESTASIS; MALE; NIDATION; PAPULAR URTICARIA; PEMPHIGOID GESTATIONIS; PREGNANCY RATE; PRIORITY JOURNAL; PRURIGO; RASH; RECURRENT DISEASE; SKIN DISEASE; SPONTANEOUS ABORTION; TREATMENT RESPONSE;

ADULT; AUTOIMMUNITY; EMBRYO IMPLANTATION; EMBRYO TRANSFER; EXANTHEMA; FEMALE; FERTILIZATION IN VITRO; GENES, MHC CLASS II; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES;

EID: 79959949019     PISSN: 10188665     EISSN: 14219832     Source Type: Journal    
DOI: 10.1159/000327377     Document Type: Article

References (20)

1. Tunzi M, Gray GR: Common skin condi-tions during pregnancy. Am Fam Physician 2007; 75: 211-218.
2. Roth MM: Pregnancy dermatoses: diagno-sis, management and controversies. Am J Clin Dermatol 2011; 12:25-41.
3. Barad D, Brill H, Gleicher N: Update on the use of dehydroepiandrosterone supplemen-tation among women with diminished ovar-ian function. J Assist Reprod Genet 2007; 24: 629-634.
4. Gleicher N, Weghofer A, Lee IH, Barad DH: FMR1 genotype with autoimmunity-associ-ated polycystic ovary-like phenotype and de-creased pregnancy chance. PLoS One 2010;5: e15303.
5. Tur-Kaspa I, Confino E, Dudkiewicz AB, Myers SA, Friberg J, Gleicher N: Ovarian stimulation protocol for in vitro fertilization with gonadotropin-releasing hormone ago-nist widens the implantation window. Fertil Steril 1990; 53: 859-864. (Pubitemid 20180476)
6. Kohler S, Hendrickson MR, Chao NJ, Smoller BR: Value of skin biopsies in assess-ing prognosis and progression of acute graft-versus-host disease. Am J Surg Pathol 1997; 21:988-996. (Pubitemid 27407282)
7. Gleicher N, Pratt D, Dudkiewicz A: What do we really know about autoantibody abnor-malities and reproductive failure: a critical review. Autoimmunity 1993; 16:115-140. (Pubitemid 24060871)
8. Gleicher N, Weghofer A, Barad D: Female infertility due to abnormal autoimmunity: frequently overlooked and greatly underap-preciated. Part I. Expert Rev Clin Obstet Gy-necol 2007; 2:453-464.
9. Baxi LV, Pearlstone MM: Subchorionic he-matomas and the presence of autoantibod-ies. Am J Obstet Gynecol 1991; 165:1423-1424.
10. Gleicher N: Why much of the pathophysiol-ogy of preeclampsia/eclampsia has to be 'au-toimmune' in nature. Am J Obstet Gynecol 2007; 196: 5.31-5.37.
11. Gleicher N: Graft-versus-host disease and immunological rejection: implications for diagnosis and treatments of pregnancy com-plications. Expert Rev Obstet Gynecol 2008; 3: 37-49. (Pubitemid 351232611)
12. Gleicher N, Elkayam U: Peripartum cardio-myopathy, an autoimmune manifestation of allograft rejection? Autoimmun Rev 2009; 8: 384-387.
13. Feng G, Chan T, Wood KJ, Bushella: Donor reactive regulatoy T cells. Curr Opin Organ Transplant 2009; 14:432-438.
14. Nelson JK, Hughes KA, Smith AG, Nisperos BB, Branchaud AM, Hansen JA: Maternal-fetal disparity in HLA class II alloantigens and pregnancy-induced amelioration of rheumatoid arthritis. N Engl J Med 1993; 329: 466-471. (Pubitemid 23222332)
15. Carp HJ, Toder V, Mashiach S: Immunother-apy of habitual abortion. Am J Reprod Im-munol 1992; 28:281-284.
16. Ober C, Steck T, van der Ven K, Billstrand C, Messer L, Kwak J, Beaman K, Beer A: MHC class II class compatibility in aborted fetuses and term infants of couples with recurrent spontaneous abortion. J Reprod Immunol 1993; 25: 195-207. (Pubitemid 24068739)
17. Takakuwa K, Higashino M, Ueda H, Yamada K, Asano K, Yasuda M, Ishii S, Kazama Y Tanaka K: Significant compatibility does not exist at the HLA-DQB gene locus in couples with unexplained recurrent abortions. Am J Reprod Immunol 1992; 28:12-16.
18. Takakuwa K, Honda K, Yokoo T, Hatava I, Tamura M, Tanaka K: Molecular genetic studies on the compatibility of HLA class II alleles in patients with unexplained recur-rent miscarriage in Japanese population. Clin Immunol 2006; 118:101-107. (Pubitemid 43012052)
19. Gleicher N, el-Roeiy A: The reproductive au-toimmune failure syndrome. Am J Obstet Gynecol 1988; 159: 223-227.
20. Geva E, Amit A, Lerner-Geva L, Lessing JB: Autoimmunity and reproduction. Fertil Steril 1997; 67: 599-611. (Pubitemid 27152363)