메뉴 건너뛰기




Volumn 152, Issue 29, 2011, Pages 1144-1155

Diabetes and risk of tumors: Oncologic considerations;Diabetes és rákkockázat az onkológus szemszögébol

Author keywords

diabetes mellitus; insulin; metformin; risk of malignancy

Indexed keywords

ANTIDIABETIC AGENT; INSULIN GLARGINE; METFORMIN;

EID: 79959925441     PISSN: 00306002     EISSN: 17886120     Source Type: Journal    
DOI: 10.1556/OH.2011.29158     Document Type: Article
Times cited : (17)

References (89)
  • 1
    • 77953782158 scopus 로고    scopus 로고
    • IDF Diabetes Atlas (article online), Available from Accessed I April 2010
    • IDF Diabetes Atlas (article online), 2009. 4th ed. Brussels, Bel gium, International Diabetes Federation. Available from www.diabetesatlas.org. Accessed I April 2010.
    • (2009) 4th Ed. Brussels, Bel Gium, International Diabetes Federation
  • 2
    • 63749101977 scopus 로고    scopus 로고
    • Eds: Boyle, P. Bernard, L. Cedex, France, World Health Organization, International Agency for Research on Cancer. Available from Accessed 1 April 2010
    • World Cancer Report: 2008 (article online), 2008. Eds: Boyle, P. Bernard, L. Cedex, France, World Health Organization, International Agency for Research on Cancer. Available from http:// www.iarc.fr/en/publications/pdfs-online/wcr/ index.php. Accessed 1 April 2010.
    • (2008) World Cancer Report: 2008 (Article Online)
  • 4
    • 0029009953 scopus 로고
    • És mtsai: Risk of pancreatic cancer following diabetes mellitus: A nationwide cohort study in Sweden
    • Chaw, W-H., Gridky, G., Nyren, O. és mtsai: Risk of pancreatic cancer following diabetes mellitus: A nationwide cohort study in Sweden. J. Natl. Cancer Inst., 1995, 87, 930-931.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 930-931
    • Chaw, W.-H.1    Gridky, G.2    Nyren, O.3
  • 6
    • 27944450832 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of colorectal cancer: A meta-analysis
    • DOI 10.1093/jnci/dji375
    • Larsson, S. C., Orsini, N., Walk, A.: Diabetes mellitus and risk of colorectal cancer: A meta-analysis. J. Natl. Cancer Inst., 2005, 97, 1679-1687. (Pubitemid 41672234) (Pubitemid 41672234)
    • (2005) Journal of the National Cancer Institute , vol.97 , Issue.22 , pp. 1679-1687
    • Larsson, S.C.1    Orsini, N.2    Wolk, A.3
  • 7
    • 34547127614 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of breast cancer: A meta-analysis
    • DOI 10.1002/ijc.22717
    • Larsson, S. C., Mantzoros, C. S., Wolk, A.: Diabetes mellitus and risk of breast cancer: A meta-analysis. Int. J. Cancer, 2007, 121, 856-862. (Pubitemid 47106217) (Pubitemid 47106217)
    • (2007) International Journal of Cancer , vol.121 , Issue.4 , pp. 856-862
    • Larsson, S.C.1    Mantzoros, C.S.2    Wolk, A.3
  • 8
    • 0031009019 scopus 로고    scopus 로고
    • Risk of endometrial and breast cancer in patients with diabetes mellitus
    • DOI 10.100 2/(SICI)10 97-0215(19970 502)71:3<3 60::AID-IJ C9>3.0.CO;2-W
    • Weiderpass, E., Gridky, G., Persson, I. és mtsai: Risk of endometrial and breast cancer in patients with diabetes mellitus. Int J. Cancer, 1997, 71, 360-363. (Pubitemid 27224297) (Pubitemid 27224297)
    • (1997) International Journal of Cancer , vol.71 , Issue.3 , pp. 360-363
    • Weiderpass, E.1    Gridley, G.2    Persson, I.3    Nyren, O.4    Ekbom, A.5    Adami, H.-O.6
  • 9
    • 3142729250 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of prostate cancer: A meta-analysis
    • Bonovas, S., Filioussi, K., Tsantes, A.: Diabetes mellitus and risk of prostate cancer: A metaanalysis. Diabctologia, 2004, 47, 1071-1078. (Pubitemid 38918167)
    • (2004) Diabetologia , vol.47 , Issue.6 , pp. 1071-1078
    • Bonovas, S.1    Filioussi, K.2    Tsantes, A.3
  • 10
    • 45749116179 scopus 로고    scopus 로고
    • Diabetes mellitus and prostate cancer risk
    • DOI 10.1002/pros.20777
    • Pierce, B. L., Plymate, S., Ostrande, E. A. és mtsai: Diabetes mellitus and prostate cancer risk. Prostate, 2008, 68, 1126-1132. (Pubitemid 351875184)
    • (2008) Prostate , vol.68 , Issue.10 , pp. 1126-1132
    • Pierce, B.L.1    Plymate, S.2    Ostrander, E.A.3    Stanford, J.L.4
  • 11
    • 55849153130 scopus 로고    scopus 로고
    • És mtsai: Diabetes mellitus and prostate cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Sreening Trial
    • Leitzmann, M. F., Ahn, J., Albanes, D. és mtsai: Diabetes mellitus and prostate cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Sreening Trial. Cancer Causes Control, 2008, 19, 1267-1276.
    • (2008) Cancer Causes Control , vol.19 , pp. 1267-1276
    • Leitzmann, M.F.1    Ahn, J.2    Albanes, D.3
  • 12
    • 79951960884 scopus 로고    scopus 로고
    • És mtsai: Diabetes mellitus and breast cancer outcomes: A systematic review and meta analysis
    • Peairs, K. S., Barone, B. B., Snyder, C. F. és mtsai: Diabetes mellitus and breast cancer outcomes: A systematic review and meta analysis. J. Clin. Oncol, 2011, 29, 40-46.
    • (2011) J. Clin. Oncol , vol.29 , pp. 40-46
    • Peairs, K.S.1    Barone, B.B.2    Snyder, C.F.3
  • 13
    • 2942520997 scopus 로고    scopus 로고
    • Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults
    • DOI 10.1093/aje/kwh161
    • Coughlin, S. S., Calle, E. E., Teras, L. R. és mtsai: Diabetes mellitus as a predictor of cancer mortality in a large cohort: of US adults. Am. J. Epidemiol., 2004, 159, 1160-1167. (Pubitemid 38747263) (Pubitemid 38747263)
    • (2004) American Journal of Epidemiology , vol.159 , Issue.12 , pp. 1160-1167
    • Coughlin, S.S.1    Calle, E.E.2    Teras, L.R.3    Petrelli, J.4    Thun, M.J.5
  • 14
    • 77951608210 scopus 로고    scopus 로고
    • És mtsai: Postoperative mortality in cancer patients with preexisting diabetes: Systematic review and meta-analysis
    • Barone, B. B., Teh, H. C., Snyder, C. F. és mtsai: Postoperative mortality in cancer patients with preexisting diabetes: Systematic review and meta-analysis. Diabetes Care, 2010, 33, 931-939.
    • (2010) Diabetes Care , vol.33 , pp. 931-939
    • Barone, B.B.1    Teh, H.C.2    Snyder, C.F.3
  • 15
    • 58049192725 scopus 로고    scopus 로고
    • És mtsai: Long-term allcause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and metaanalysis
    • Barone, B. B., Teh, H. C., Snyder, C. P. és mtsai: Long-term allcause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and metaanalysis. JAMA, 2008, 300, 2754-2764.
    • (2008) JAMA , vol.300 , pp. 2754-2764
    • Barone, B.B.1    Teh, H.C.2    Snyder, C.P.3
  • 16
    • 58049192725 scopus 로고    scopus 로고
    • És mtsai: Long-term allcause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and metaanalysis
    • Barone, B. B., Teh, H. C., Snyder, C. F. és mtsai: Long-term allcause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and metaanalysis. JAMA, 2008, 300, 2754-2764.
    • (2008) JAMA , vol.300 , pp. 2754-2764
    • Barone, B.B.1    Teh, H.C.2    Snyder, C.F.3
  • 17
    • 77955560604 scopus 로고    scopus 로고
    • És mtsai: Diabetes, prediabetes and cancer mortality
    • Zhou, X. H., Qiao, Q., Zetkelius, B. és mtsai: Diabetes, prediabetes and cancer mortality. Diabctologia, 2010, 53, 1867-1876.
    • (2010) Diabctologia , vol.53 , pp. 1867-1876
    • Zhou, X.H.1    Qiao, Q.2    Zetkelius, B.3
  • 18
    • 77951006620 scopus 로고    scopus 로고
    • És mtsai: Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
    • Hassan, M. M., Cttrley, S. A., Li, D. és mtsai: Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma. Cancer, 2010, 116, 1938-1946.
    • (2010) Cancer , vol.116 , pp. 1938-1946
    • Hassan, M.M.1    Cttrley, S.A.2    Li, D.3
  • 19
    • 79959978627 scopus 로고    scopus 로고
    • Diabetes and insulin duration and cancer incidence: A register linkage study in Denmark
    • Carstensen, B., Witte, D. R, Friis, S.: Diabetes and insulin duration and cancer incidence: A register linkage study in Denmark. Diabetologia, 2010, 5.3 (Suppl. 1) , S67.
    • (2010) Diabetologia , vol.53 , Issue.SUPPL. 1 , pp. 67
    • Carstensen, B.1    Witte, D.R.2    Friis, S.3
  • 20
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
    • Calle, E. E., Kaaks, R.: Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat. Rev. Cancer, 2004, 4, 579-591. (Pubitemid 39025053) (Pubitemid 39025053)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.8 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 21
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. Adults
    • DOI 10.1056/NEJMoa021423
    • Calle, E. E., Rodriguez, C., Walker-Thurmond, K. és mtsai: Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N. Engl. J. Med., 2003, 348, 1625-1638. (Pubitemid 36459468) (Pubitemid 36459468)
    • (2003) New England Journal of Medicine , vol.348 , Issue.17 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3    Thun, M.J.4
  • 22
    • 38149065087 scopus 로고    scopus 로고
    • Az elhízás szerepe a vastagbéldaganatok kialakulásában
    • Hagymási K., Tulassay Zs.: Az elhízás szerepe a vastagbéldaganatok kialakulásában. Orv. Hetil., 2007, 148, 2411-2415.
    • (2007) Orv. Hetil. , vol.148 , pp. 2411-2415
    • Hagymási, K.1    Tulassay, Zs.2
  • 23
    • 68449094325 scopus 로고    scopus 로고
    • The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
    • Currie, C. J., Poole, C. D, Gale, E. A. M.: The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabctologia, 2009, 52, 1766-1777.
    • (2009) Diabctologia , vol.52 , pp. 1766-1777
    • Currie, C.J.1    Poole, C.D.2    Gale, E.A.M.3
  • 24
    • 67650874081 scopus 로고    scopus 로고
    • És mtsai: Cancer statistics, 2009
    • Jemai, A., Siegel, R., Ward, E. és mtsai: Cancer statistics, 2009. CA Cancer J. Clin., 2009, 59, 225-249.
    • (2009) CA Cancer J. Clin. , vol.59 , pp. 225-249
    • Jemai, A.1    Siegel, R.2    Ward, E.3
  • 26
    • 33748414239 scopus 로고    scopus 로고
    • Body mass index history and risk of type 2 diabetes: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
    • Schienkiewitz, A., Schulze, M. B., Hoffmann, K. és mtsai: Body mass index history and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Am. J. Clin. Nutr., 2006, 84, 427-433. (Pubitemid 44699156) (Pubitemid 44699156)
    • (2006) American Journal of Clinical Nutrition , vol.84 , Issue.2 , pp. 427-433
    • Schienkiewitz, A.1    Schulze, M.B.2    Hoffmann, K.3    Kroke, A.4    Boeing, H.5
  • 27
    • 0032957363 scopus 로고    scopus 로고
    • Emerging epidemic of type 2 diabetes in youth
    • DOI 10.2337/diacare.22.2.345
    • Rosenbloom, A. L., Joe, J. R., Toung, R. S. és mtsai: Emerging epidemic of type 2 diabetes in youth. Diabetes Care, 1999, 22, 345-354. (Pubitemid 29056933) (Pubitemid 29056933)
    • (1999) Diabetes Care , vol.22 , Issue.2 , pp. 345-354
    • Rosenbloom, A.L.1    Joe, J.R.2    Young, R.S.3    Winter, W.E.4
  • 28
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies
    • DOI 10.1016/S0140-6736(08)60269-X, PII S014067360860269X
    • Renehan, A. G., Tyson, M., Egger, M. és mtsai: Body mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies. Lancet, 2008, 371, 569-578. (Pubitemid 351232031) (Pubitemid 351232031)
    • (2008) The Lancet , vol.371 , Issue.9612 , pp. 569-578
    • Renehan, A.G.1    Tyson, M.2    Egger, M.3    Heller, R.F.4    Zwahlen, M.5
  • 29
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
    • Calle, E. E., Kaaks, R.: Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat. Rev. Cancer, 2004, 4, 579-591. (Pubitemid 39025053) (Pubitemid 39025053)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.8 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 30
    • 85047174307 scopus 로고    scopus 로고
    • Szabé, Gy. és mtsa: Increased prevalence of diabetes and obesity in patients with salivary gland tumors
    • Suba, Zs., Barabás, J., Szabé, Gy. és mtsa: Increased prevalence of diabetes and obesity in patients with salivary gland tumors. Diabet. Care, 2005, 28, 228-230.
    • (2005) Diabet. Care , vol.28 , pp. 228-230
    • Suba, Zs.1    Barabás, J.2
  • 33
    • 61549094077 scopus 로고    scopus 로고
    • És mtsai: Weight and type 2 diabetes after bariatric surgery: Systematic review and metaanalysis
    • Buchwald, H., Estok, R., Fahrbach, K. és mtsai: Weight and type 2 diabetes after bariatric surgery: Systematic review and metaanalysis. Am. J. Med., 2009, 122, 248-256.
    • (2009) Am. J. Med. , vol.122 , pp. 248-256
    • Buchwald, H.1    Estok, R.2    Fahrbach, K.3
  • 35
    • 33749522888 scopus 로고    scopus 로고
    • Guidelines Advisory Committee: American Cancer Society guidelines on nutrition and physical activity for cancer prevention: Reducing the risk of cancer with healthy food choices and physical activity
    • Guidelines Advisory Committee: American Cancer Society guidelines on nutrition and physical activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA. Cancer J. Clin., 2006, 56, 254-281.
    • (2006) CA. Cancer J. Clin. , vol.56 , pp. 254-281
  • 37
    • 60149102248 scopus 로고    scopus 로고
    • És mtsai: Dietary glycemic index, glycemic load, and risk of cancer: A prospective cohort study
    • George, S. M., Mayne, S. T, Leitzmann, M. F. és mtsai: Dietary glycemic index, glycemic load, and risk of cancer: A prospective cohort study. Am. J. Epidemiol., 2009, 169, 462-472.
    • (2009) Am. J. Epidemiol. , vol.169 , pp. 462-472
    • George, S.M.1    Mayne, S.T.2    Leitzmann, M.F.3
  • 38
    • 0242407660 scopus 로고    scopus 로고
    • Physical activity and cancer prevention-data from epidemiologic studies
    • Lee, I. M.: Physical activity and cancer prevention-data from epidemiologic studies. Med. Sci. Sports Exerc., 2003, 35, 1823-1827.
    • (2003) Med. Sci. Sports Exerc. , vol.35 , pp. 1823-1827
    • Lee, I.M.1
  • 40
    • 0742301241 scopus 로고    scopus 로고
    • Effect, of alcohol consumption on diabetes mellitus: A systematic review
    • Howard, A. A., Arruten, J. H., Gourevitch, M. N.: Effect, of alcohol consumption on diabetes mellitus: A systematic review. Ann. Intern. Med., 2004, 140, 211-219.
    • (2004) Ann. Intern. Med. , vol.140 , pp. 211-219
    • Howard, A.A.1    Arruten, J.H.2    Gourevitch, M.N.3
  • 41
    • 70449394764 scopus 로고    scopus 로고
    • És mtsai: Alcohol as a risk factor for type 2 diabetes: A systematic review and meta-analysis
    • Baliunas, D. O., Taylor, B. J., Irving, H. és mtsai: Alcohol as a risk factor for type 2 diabetes: A systematic review and meta-analysis. Diabetes Care, 2009, 32, 2123-2132.
    • (2009) Diabetes Care , vol.32 , pp. 2123-2132
    • Baliunas, D.O.1    Taylor, B.J.2    Irving, H.3
  • 42
    • 0036512939 scopus 로고    scopus 로고
    • És mtsai: Insulin: A novel factor in cancerogenesis
    • Gupta, K., Krishnaswamy, G., Karnad, A. és mtsai: Insulin: A novel factor in cancerogenesis. Am. J. Med. Sci., 2002, 323, 140-145.
    • (2002) Am. J. Med. Sci. , vol.323 , pp. 140-145
    • Gupta, K.1    Krishnaswamy, G.2    Karnad, A.3
  • 43
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak, M.: Insulin and insulin-like growth factor signalling in neoplasia. Nat. Rev. Cancer, 2008, 8, 915-928.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 915-928
    • Pollak, M.1
  • 44
    • 0030690195 scopus 로고    scopus 로고
    • Insulin stimulates the phosphorylation and activity of farnesyltransferase via the Ras-mitogen-activated protein kinase pathway
    • Goalstone, M. L., Carel, K., Ijtitner, J. W. és mtsai: Insulin, stimulates the phosphorylation, and activity of farnesyltransferase via the Ras-Map kinase pathway. Endocrinology, 1997, 138, 5119-5124. (Pubitemid 27509668) (Pubitemid 27509668)
    • (1997) Endocrinology , vol.138 , Issue.12 , pp. 5119-5124
    • Goalstone, M.1    Carel, K.2    Leitner, J.W.3    Draznin, B.4
  • 46
    • 68149134500 scopus 로고    scopus 로고
    • Growth effects of insulin and insulin analogues
    • Sandow, J.: Growth effects of insulin and insulin analogues. Arch. Physiol. Biochem., 2009, 115, 72-85.
    • (2009) Arch. Physiol. Biochem. , vol.115 , pp. 72-85
    • Sandow, J.1
  • 47
    • 58249092146 scopus 로고    scopus 로고
    • És mtsai: Insulin, the insulin like growth factor axis, and mortality in patients with nonmetastatic colorectal, cancer
    • Wolpin, B. M., Meyerhardt, J. A., Chan, A. T. és mtsai: Insulin, the insulin like growth factor axis, and mortality in patients with nonmetastatic colorectal, cancer. J. Clin. Oncol., 2009, 27, 176-185.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 176-185
    • Wolpin, B.M.1    Meyerhardt, J.A.2    Chan, A.T.3
  • 48
    • 33645766204 scopus 로고    scopus 로고
    • Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
    • Bowker, S. L., Majumdar, S. R., Veugelers, P. és mtsa: Increased, cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care, 2006, 29, 254-258. (Pubitemid 44106500) (Pubitemid 44106500)
    • (2006) Diabetes Care , vol.29 , Issue.2 , pp. 254-258
    • Bowker, S.L.1    Majumdar, S.R.2    Veugelers, P.3    Johnson, J.A.4
  • 49
    • 68149131125 scopus 로고    scopus 로고
    • Obesity related hyperinsulinaemia and hyperglycaemia and cancer development
    • Becker, S., DOSSMS, L., Kaaks, R.: Obesity related hyperinsulinaemia and hyperglycaemia and cancer development. Arch. Physiol. Biochem., 2009, 115, 86-96.
    • (2009) Arch. Physiol. Biochem. , vol.115 , pp. 86-96
    • Becker, S.1    Dossms, L.2    Kaaks, R.3
  • 50
    • 52649177215 scopus 로고    scopus 로고
    • Effects of chronic hyperinsulinemia in insulin resistant patients
    • Muntoni, S., Muntoni, S., Draznin, B.: Effects of chronic hyperinsulinemia in insulin resistant patients. Curr. Diab. Rep., 2008, 8, 233-238.
    • (2008) Curr. Diab. Rep. , vol.8 , pp. 233-238
    • Muntoni, S.1    Muntoni, S.2    Draznin, B.3
  • 51
    • 58349099006 scopus 로고    scopus 로고
    • A metabolikus szindróma és a 2-es típusú diabetes mellitus mint, rosszindulatú daganatra hajlamosító állapotok
    • Halmos T., Suba I.: A metabolikus szindróma és a 2-es típusú diabetes mellitus mint, rosszindulatú daganatra hajlamosító állapotok. Orv. Hetil., 2008, 149, 2403-2411.
    • (2008) Orv. Hetil. , vol.149 , pp. 2403-2411
    • Halmos, T.1    Suba, I.2
  • 52
    • 33750097723 scopus 로고    scopus 로고
    • Az inzulinrezisztencia és a daganat. összefüggé sei
    • Suba Zs., Ujpál M.: Az inzulinrezisztencia és a daganat. összefüggései. Magyar Ontologia, 2006, 50, 127-135.
    • (2006) Magyar Ontologia , vol.50 , pp. 127-135
    • Suba, Zs.1    Ujpál, M.2
  • 53
    • 32944456385 scopus 로고    scopus 로고
    • És mtsai: Az inzulinrezisztencia és a nyá lmirigydaganatok epidemiológiai összeruggései
    • Suba Zs., Barabás J., Takács D. és mtsai: Az inzulinrezisztencia és a nyálmirigydaganatok epidemiológiai összeruggései. Orv. Hetil., 2005, 146, 1727-1732.
    • (2005) Orv. Hetil. , vol.146 , pp. 1727-1732
    • Suba, Zs.1    Barabás, J.2    Takács, D.3
  • 57
    • 34047174592 scopus 로고    scopus 로고
    • The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer
    • DOI 10.2174/138161207780249173
    • Belfiore, A.: The role of insulinreceptor isoforms and hybrid insulin/IGF-1 receptors in human cancer. Curr. Pharm. Des., 2007, 13, 671-686. (Pubitemid 46510744)
    • (2007) Current Pharmaceutical Design , vol.13 , Issue.7 , pp. 671-686
    • Belfiore, A.1
  • 58
    • 44449097168 scopus 로고    scopus 로고
    • AGE-RAGE system and carcinogenesis
    • DOI 10.2174/138161208784139765
    • Abe, R., Yamagishi, S.: AGE-RAGE system and carcinogenesis. Curr. Pharm. Des., 2008, 14, 940-945. (Pubitemid 351753280) (Pubitemid 351753280)
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.10 , pp. 940-945
    • Abe, R.1    Yamagishi, S.-I.2
  • 60
    • 79959949077 scopus 로고    scopus 로고
    • Oxidatív stressz diabetes mellitusban. Diabetes mellitus, elmélet és klinikum
    • Szerk.: Halmos T., Jermendy Gy
    • Somogyi A.: Oxidatív stressz diabetes mellitusban. In: Diabetes mellitus, elmélet és klinikum. Szerk.: Halmos T., Jermendy Gy. Medicina Könyvkiadó, Budapest, 2002, 179-195.
    • (2002) Medicina Könyvkiadó, Budapest , pp. 179-195
    • Somogyi, A.1
  • 61
    • 33646404099 scopus 로고    scopus 로고
    • És mtsai: Fasting blood, glucose and cancer risk in a cohort of more than 140,000 adults in Austria
    • Rapp, K., Schroeder, J., Klenk, J. és mtsai: Fasting blood, glucose and cancer risk in a cohort of more than 140,000 adults in Austria. Diabctologia, 2006, 49, 945-952.
    • (2006) Diabctologia , vol.49 , pp. 945-952
    • Rapp, K.1    Schroeder, J.2    Klenk, J.3
  • 64
    • 79959950256 scopus 로고    scopus 로고
    • Diabetes, diabetes-kezelés és neoplasia. Biztonságosak-e az antidiabetikus készítmények?
    • Gero L.: Diabetes, diabetes-kezelés és neoplasia. Biztonságosak-e az antidiabetikus készítmények? Diabetologia Hungarica, 2009, 17, 313-322.
    • (2009) Diabetologia Hungarica , vol.17 , pp. 313-322
    • Gero, L.1
  • 65
    • 65349175605 scopus 로고    scopus 로고
    • És mtsai: Metformin inhibits breast, cancer cell growth, colony formation and induces cell cycle arrest in vitro
    • Alimova, I. N., Liu, B., Fan, Z. és mtsai: Metformin inhibits breast, cancer cell growth, colony formation and induces cell cycle arrest in vitro. Cell Cycle, 2009, 8, 909-915.
    • (2009) Cell Cycle , vol.8 , pp. 909-915
    • Alimova, I.N.1    Liu, B.2    Fan, Z.3
  • 66
    • 67650096912 scopus 로고    scopus 로고
    • És mtsai: Enhancing CD8 T cell memory by modulating fatty acid metabolism
    • Pierce, E. L., Walsh, M. C., Cejas, P. J. és mtsai: Enhancing CD8 T cell memory by modulating fatty acid metabolism. Nature, 2009, 460, 103-107.
    • (2009) Nature , vol.460 , pp. 103-107
    • Pierce, E.L.1    Walsh, M.C.2    Cejas, P.J.3
  • 67
    • 36348950449 scopus 로고    scopus 로고
    • Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
    • DOI 10.1158/0008-5472.CAN-07-2310
    • Dowling, R. J., Zakikhani, M., Fantus, I. G. és mtsai: Metformin inhibits mammalian target of rapamycin dependent translation initiation in breast cancer cells. Cancer Res., 2007, 67, 10804-10812. (Pubitemid 350145909) (Pubitemid 350145909)
    • (2007) Cancer Research , vol.67 , Issue.22 , pp. 10804-10812
    • Dowling, R.J.O.1    Zakikhani, M.2    Fantus, I.G.3    Pollak, M.4    Sonenberg, N.5
  • 68
    • 70350236538 scopus 로고    scopus 로고
    • És mtsa: Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
    • Hirsch, H A., Iliopoulos, D., Tsichlis, P. N. és mtsa: Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res., 2009, 69, 7507-7511.
    • (2009) Cancer Res. , vol.69 , pp. 7507-7511
    • Hirsch, H.A.1    Iliopoulos, D.2    Tsichlis, P.N.3
  • 70
    • 78649302320 scopus 로고    scopus 로고
    • És mtsai: Metformin and cancer risk in diabetic patients: A systematic review and metaanalysis
    • DeCensi, A., Puntoni, M., Goodwin, P. és mtsai: Metformin and cancer risk in diabetic patients: A systematic review and metaanalysis. Cancer Prev. Res. (Phila), 2010, 3, 1451-1461.
    • (2010) Cancer Prev. Res. (Phila) , vol.3 , pp. 1451-1461
    • DeCensi, A.1    Puntoni, M.2    Goodwin, P.3
  • 71
    • 75149179169 scopus 로고    scopus 로고
    • És mtsai: Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16
    • Landman, G. W, Kleefstra, N., van Hateren, K.J. és mtsai: Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16. Diabetes Care, 2010, 33, 322-326.
    • (2010) Diabetes Care , vol.33 , pp. 322-326
    • Landman, G.W.1    Kleefstra, N.2    Van Hateren, K.J.3
  • 72
    • 34248192254 scopus 로고    scopus 로고
    • És mtsai: Thiazolidinediones and the risk of lung, prostate and colon cancer in patients with diabetes
    • Govindarjan, R., Ratnasinghe, L., Simmonds, D. L. és mtsai: Thiazolidinediones and the risk of lung, prostate and colon cancer in patients with diabetes. J. Clin. Oncol., 2007, 25, 1461-1462.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 1461-1462
    • Govindarjan, R.1    Ratnasinghe, L.2    Simmonds, D.L.3
  • 73
    • 25144475465 scopus 로고    scopus 로고
    • PPARγ as a therapeutic target for tumor angiogenesis and metastasis
    • Panigrahy, D., Huang, S., Kieran, M. W. és mtsa: PPARgamma as a therapeutic target for tumor angiogenesis and metastasis. Cancer Biol. Ther., 2005, 4, 687-693. (Pubitemid 41351164) (Pubitemid 41351164)
    • (2005) Cancer Biology and Therapy , vol.4 , Issue.7 , pp. 687-693
    • Panigrahy, D.1    Huang, S.2    Kieran, M.W.3    Kaipainen, A.4
  • 74
    • 58849143927 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor gamma pathway targeting in carcinogenesis: Implications for chemoprcvention
    • Ondrey, F.: Peroxisome proliferatoractivated receptor gamma pathway targeting in carcinogenesis: implications for chemoprcvention. Clin. Cancer Res., 2009, 15, 2-8.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 2-8
    • Ondrey, F.1
  • 75
    • 49649107776 scopus 로고    scopus 로고
    • És mtsa: Rosiglitazone and risk of cancer: A meta-analysis of randomized clinical trials
    • Monami, M., Lamanna, C., Marchionni, N. és mtsa: Rosiglitazone and risk of cancer: A meta-analysis of randomized clinical trials. Diabetes Care, 2008, 31, 1455-1460.
    • (2008) Diabetes Care , vol.31 , pp. 1455-1460
    • Monami, M.1    Lamanna, C.2    Marchionni, N.3
  • 76
    • 33645766204 scopus 로고    scopus 로고
    • Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
    • Bowker, S. L., Majumdar, S. R., Veugelers, P. és mtsa: Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin, Diabetes Care, 2006, 29, 254-258. (Pubitemid 44106500) (Pubitemid 44106500)
    • (2006) Diabetes Care , vol.29 , Issue.2 , pp. 254-258
    • Bowker, S.L.1    Majumdar, S.R.2    Veugelers, P.3    Johnson, J.A.4
  • 77
    • 70449533135 scopus 로고    scopus 로고
    • És mtsai: Sulphonylurcas and cancer: A case-control study
    • Monami, M., Lamanna, C., Balzi, D. és mtsai: Sulphonylurcas and cancer: A case-control study. Acta Diabetol., 2009, 46, 279-284.
    • (2009) Acta Diabetol. , vol.46 , pp. 279-284
    • Monami, M.1    Lamanna, C.2    Balzi, D.3
  • 78
    • 67650504265 scopus 로고    scopus 로고
    • És mtsai: Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines
    • Shukla, A., Grisouard, J., Ehemann, V. és mtsai: Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines. Endocr. Relat. Cancer, 2009, 16, 429-441,
    • (2009) Endocr. Relat. Cancer , vol.16 , pp. 429-441
    • Shukla, A.1    Grisouard, J.2    Ehemann, V.3
  • 79
    • 65549138380 scopus 로고    scopus 로고
    • És mtsai: Insulin analogues display IGF-I-like mitogenic and antiapoptotic activities in cultured cancer cells
    • Weinstein, D., Simon, M., Tehezkel, E. és mtsai: Insulin analogues display IGF-I-like mitogenic and antiapoptotic activities in cultured cancer cells. Diabetes Metab. Res. Rev., 2009, 25, 1-49.
    • (2009) Diabetes Metab. Res. Rev. , vol.25 , pp. 1-49
    • Weinstein, D.1    Simon, M.2    Tehezkel, E.3
  • 80
    • 0342657181 scopus 로고    scopus 로고
    • Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
    • Kurtzhals, P., Schäffer, L., Sørensen, A. és mtsai: Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed, for clinical use. Diabetes, 2000, 49, 999-1005. (Pubitemid 30349423) (Pubitemid 30349423)
    • (2000) Diabetes , vol.49 , Issue.6 , pp. 999-1005
    • Kurtzhals, P.1    Schaffer, L.2    Sorensen, A.3    Kristensen, C.4    Jonassen, I.5    Schmid, C.6    Trub, T.7
  • 81
    • 68149134500 scopus 로고    scopus 로고
    • Growth effects of insulin and insulin analogues
    • Sandow, J.: Growth effects of insulin and insulin analogues. Arch. Physiol. Biochem., 2009, 115, 72-85.
    • (2009) Arch. Physiol. Biochem. , vol.115 , pp. 72-85
    • Sandow, J.1
  • 82
    • 68449104156 scopus 로고    scopus 로고
    • És mtsai: Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: A cohort study
    • Hemkens, L. G., Grouven, U., Bender, R. és mtsai: Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: A cohort study. Diabctologia, 2009, 52, 1732-1744.
    • (2009) Diabctologia , vol.52 , pp. 1732-1744
    • Hemkens, L.G.1    Grouven, U.2    Bender, R.3
  • 83
    • 68449104625 scopus 로고    scopus 로고
    • És mtsai: Insulin glargine use and short-term incidence of malignancies - A population based follow-up study in Sweden
    • Jonasson, J. M., Ljung, R., Talbäck, M. és mtsai: Insulin glargine use and short-term incidence of malignancies - a population based follow-up study in Sweden. Diabetologia, 2009, 52, 1745-1754.
    • (2009) Diabetologia , vol.52 , pp. 1745-1754
    • Jonasson, J.M.1    Ljung, R.2    Talbäck, M.3
  • 84
    • 68449094354 scopus 로고    scopus 로고
    • SDRN Epidemiology Group: Use of insulin glargine and cancer incidence in Scotland: A study from the Scottish Diabetes Research
    • Network Epidemiology Group
    • Calhoun, H. M., SDRN Epidemiology Group: Use of insulin glargine and cancer incidence in Scotland: A study from the Scottish Diabetes Research. Network Epidemiology Group. Diabetologia, 2009, 52, 1755-1765.
    • (2009) Diabetologia , vol.52 , pp. 1755-1765
    • Calhoun, H.M.1
  • 85
    • 68449088653 scopus 로고    scopus 로고
    • És mtsai: Similar risk of malignancy with insulin glargine and neutral protamine Hage dorn (NPH) insulin in patients with, type 2 diabetes: Findings from a 5 year randomised, open-label study
    • Rosenstock, J., Fonseca, V., McGill, J. B. és mtsai: Similar risk of malignancy with insulin glargine and neutral protamine Hage dorn (NPH) insulin in patients with, type 2 diabetes: findings from a 5 year randomised, open-label study. Diabetologia, 2009, 52, 1971-1973.
    • (2009) Diabetologia , vol.52 , pp. 1971-1973
    • Rosenstock, J.1    Fonseca, V.2    McGill, J.B.3
  • 86
    • 68449088664 scopus 로고    scopus 로고
    • Does diabetes therapy influence the risk of cancer?
    • Smith, U., Gale, E. A.: Does diabetes therapy influence the risk of cancer? Diabetologia, 2009, 52, 1699-1708.
    • (2009) Diabetologia , vol.52 , pp. 1699-1708
    • Smith, U.1    Gale, E.A.2
  • 87
    • 75849119306 scopus 로고    scopus 로고
    • Does insulin therapy promote, reduce, or have a neutral effect on cancers?
    • Gerstein, H. C.: Does insulin therapy promote, reduce, or have a neutral effect on cancers? JAMA, 2010, 303, 446-447.
    • (2010) JAMA , vol.303 , pp. 446-447
    • Gerstein, H.C.1
  • 88
    • 70450201557 scopus 로고    scopus 로고
    • Insulin glargine and cancer: Cause and effect unproven
    • Owens, D. R., Rosenstock, J., Bolli, G. B.: Insulin glargine and cancer: cause and effect unproven. Pract. Diab. Int., 2009, 26, 256-257.
    • (2009) Pract. Diab. Int. , vol.26 , pp. 256-257
    • Owens, D.R.1    Rosenstock, J.2    Bolli, G.B.3
  • 89
    • 68349148204 scopus 로고    scopus 로고
    • Insulin glargine and malignancy: An unwarranted alarm
    • Pocock, S. J., Smeeth, L.: Insulin glargine and malignancy: An unwarranted alarm. Lancet, 2009, 374, 511-513.
    • (2009) Lancet , vol.374 , pp. 511-513
    • Pocock, S.J.1    Smeeth, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.