The influence of porcine pancreas digestion parameters and islet histomorphology on islet isolation outcome

Polish Journal of Veterinary Sciences

Volumn 14, Issue 2, 2011, Pages 227-230

  Kinasiewicz, J ^a   Sabat, M ^b   Antosiak Iwanska M ^a   Godlewska, E ^a   Sitarek, E ^b   Orlowski T ^a,b  

^a INSTITUTE OF BIOCYBERNETICS AND BIOMEDICAL ENGINEERING   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Islet histomorphology; Isolation parameters; Pig islets

Indexed keywords

ANIMAL; ARTICLE; CYTOLOGY; FEMALE; METHODOLOGY; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PHYSIOLOGY; SWINE; TRANSPLANTATION;

ANIMALS; FEMALE; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; SWINE; TISSUE AND ORGAN HARVESTING;

SUIDAE; SUS;

EID: 79959917606     PISSN: 15051773     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10181-011-0034-7     Document Type: Article

References (15)

1. Calafiore R (2003) Alginate microcapsules for pancreatic islet cell graft immunoprotection: struggle and progress towards the final cure for type 1 diabetes mellitus. Expert Opin Biol Ther 3: 201-205.
2. De Vos P, De Haan BJ, Wolters GH, Strubbe JH, Van Schilfgaarde R (1997) Improved biocompatibility but limited graft survival after purification of alginate for microencapsulation of pancreatic islets. Diabetologia 40: 262-270. (Pubitemid 27096549)
3. Dufrane D, Goebbels RM, Fdilat I, Guiot Y, Gianello P (2005) Impact of porcine islet size on cellular structure and engraftment after transplantation: adult versus young pigs. Pancreas 30: 138-147. (Pubitemid 40289451)
4. Khan MH, Harlan DM (2009) Counterpoint: clinical islet transplantation: not ready for prime time. Diabetes Care 32: 1570-1574.
5. Kim JH, Kim HI, Lee KW, Yu JE, Kim SH, Park HS, Park CG, Ihm SH, Ha J, Kim SJ, Lee HK, Ahn C, Park KS (2007) Influence of strain and age differences on the yields of porcine islet isolation: extremely high islet yields from SPF CMS miniature pigs. Xenotransplantation 14: 60-66. (Pubitemid 46051370)
6. Krickhahn M, Buhler C, Meyer T, Thiede A, Ulrichs K (2002) The morphology of islets within the porcine donor pancreas determines the isolation result: successful isolation of pancreatic islets can now be achieved from young market pigs. Cell Transplant 11: 827-838. (Pubitemid 36176795)
7. Lim F, Sun AM (1980) Microencapsulated islets as bioartificial endocrine pancreas. Science 210: 908-910. (Pubitemid 11169847)
8. Merani S, Shapiro AM (2006) Current status of pancreatic islet transplantation. Clin Sci (Lond) 110: 611-625. (Pubitemid 43844731)
9. O'Neil JJ, Stegemann JP, Nicholson DT, Gagnon KA, Solomon BA, Mullon CJ (2001) The isolation and function of porcine islets from market weight pigs. Cell Transplant 10: 235-246. (Pubitemid 32565803)
10. Sabat M, Godlewska E, Kinasiewicz J, Urbanowicz A, Ortowski T (2003) Assessment of some porcine strains as donors of islets of Langerhans. Transplant Proc 35: 2343-2344. (Pubitemid 37194412)
11. Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV (2000) Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343: 230-238. (Pubitemid 30490390)
12. Socci C, Ricordi C, Davalli AM, Staudacher C, Baro P, Vertova A, Freschi M, Gavazzi F, Braghi S, Pozza G (1990) Selection of donors significantly improves pig islet isolation yield. Horm Metab Res Suppl 25: 32-34.
13. Tibell A, Groth CG, Moller E, Korsgren O, Andersson A, Hellerstrom C (1994) Pig-to-human islet transplantation in eight patients. Transplant Proc 26: 762-763. (Pubitemid 24143720)
14. Toso C, Brandhorst D, Oberholzer J, Triponez F, Buhler L, Morel P (2000) Isolation of adult porcine islets of Langerhans. Cell Transplant 9: 297-305. (Pubitemid 30655682)
15. Ulrichs K, Bosse M, Wacker HH, Heiser A, Muller-Ruchholtz W (1994) Histologic analysis of the porcine pancreas to improve islet yield and integrity after collagenase digestion. Transplant Proc 26: 610-612. (Pubitemid 24143627)