Fragmentation of embryos is associated with both necrosis and apoptosis

Fertility and Sterility

Volumn 96, Issue 1, 2011, Pages 187-192

  Chi, Hee Jun ^a   Koo, Jung Jin ^b   Choi, Soon Young ^a   Jeong, Hyeon Jeong ^a   Roh, Sung Il ^a  

^a Mizmedi Hospital   (South Korea)

^b Hanna Women's Clinic   (South Korea)

Author keywords

apoptosis; Embryo fragmentation; fragment removal; necrosis; secondary necrosis

Indexed keywords

ADENOSINE TRIPHOSPHATE;

APOPTOSIS; ARTICLE; BLASTOMERE; DNA FRAGMENTATION; EMBRYO; EMBRYO FRAGMENTATION; HUMAN; HUMAN TISSUE; MITOCHONDRION; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL;

ADULT; ANIMALS; APOPTOSIS; DNA FRAGMENTATION; EMBRYO TRANSFER; EMBRYO, MAMMALIAN; FEMALE; HUMANS; MICE; NECROSIS; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 79959908817     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2011.04.020     Document Type: Article

References (32)

1. M. Alikani, J. Cohen, G. Tomkin, G.J. Garrisi, C. Mack, and R.T. Scott Human embryo fragmentation in vitro and its implications for pregnancy and implantation Fertil Steril 71 1999 836 842 (Pubitemid 29206907)
2. M. Alikani, G. Calderon, G. Tomkin, J. Garrisi, M. Kokot, and J. Cohen Cleavage anomalies in early human embryos and survival after prolonged culture in-vitro Hum Reprod 15 2000 2634 2643 (Pubitemid 32000523)
3. J. Van Blerkom, P. Davis, and S. Alexander A microscopic and biochemical study of fragmentation phenotypes in stage-appropriate human embryos Hum Reprod 16 2001 719 729 (Pubitemid 32293802)
4. T. Ebner, C. Yaman, M. Moser, M. Sommergruber, W. Pölz, and G. Tews Embryo fragmentation in vitro and its impact on treatment and pregnancy outcome Fertil Steril 76 2001 281 285 (Pubitemid 32703815)
5. A. Jurisicova, S. Varmuza, and R.F. Casper Programmed cell death and human embryo fragmentation Mol Hum Reprod 2 1996 93 98 (Pubitemid 126715855)
6. H.C. Liu, Z.Y. He, C.A. Mele, L.L. Veeck, O. Davis, and Z. Rosenwaks Expression of apoptosis-related genes in human oocytes and embryos J Assist Reprod Genet 17 2000 521 533
7. D. Mevorach, U. Trahtemberg, A. Krispin, M. Attalah, J. Zazoun, and A. Tabib What do we mean when we write senescence, apoptosis, necrosis or clearance of dying cells? Ann NY Acad Sci 1209 2010 1 9
8. D. Kanduc, A. Mittleman, R. Sperpico, E. Sinigaglia, A. Sinha, and C. Natale Cell death: apoptosis versus necrosis (Review) Int J Oncol 21 2002 165 170
9. M.T. Silva Secondary necrosis: the natural outcome of thee complete apoptotic program FEBS Letters 584 2010 4491 4499
10. R. Levy Genetic regulation of preimplantation embryo survival Int Rev Cytol 210 2001 1 37 (Pubitemid 32888799)
11. K. Hardy, and S. Spanos Growth factor expression and function in the human and mouse preimplantation embryo J Endocrinol 172 2002 221 236 (Pubitemid 34183071)
12. M.A. Bedaiwy, A. Agarwal, T.M. Said, J.M. Goldberg, R.K. Sharma, and S.E. Worley Role of total antioxidant capacity in the differential growth of human embryos in vitro Fertil Steril 86 2006 304 309 (Pubitemid 44137445)
13. Y. Kitagawa, K. Suzuki, A. Yoneda, and T. Watanabe Effects of oxygen concentration and antioxidants on the in vitro developmental ability, production of reactive oxygen species (ROS), and DNA fragmentation in porcine embryos Theriogenology 62 2004 1186 1197 (Pubitemid 39123698)
14. D. Fabian, J. Koppel, and P. Maddox-Hyttel Apoptotic processes during mammalian pre-implantation development Theriogenology 64 2005 221 231 (Pubitemid 40793674)
15. M. Kamjoo, D.R. Brison, and S.J. Kimber Apoptosis in the preimplantation mouse embryo: effect of strain difference and in vitro culture Mol Reprod Dev 61 2002 67 77 (Pubitemid 135715267)
16. A.D. Metcalfe, H.R. Hunter, D.J. Bloor, B.A. Lieberman, H.M. Picton, and H.J. Leese Expression of 11 members of the BCL-2 family of apoptosis regulatory molecules during human preimplantation embryo development and fragmentation Mol Reprod Dev 68 2004 35 50 (Pubitemid 38420517)
17. M.T. Silva, A. do Vale, and N.M. dos Santos Secondary necrosis in multicellular animals: an outcome of apoptosis with pathogenic implications Apoptosis 13 2008 463 482
18. M.D. Keltz, J.C. Skorupski, K. Bradley, and D. Stein Predictors of embryo fragmentation and outcome after fragment removal in in vitro fertilization Fertil Steril 86 2006 321 324 (Pubitemid 44118978)
19. J. Cohen, M. Alikani, H.C. Liu, and Z. Rosenwaks Rescue of human embryos by micromanipulation Baillieres Clin Obstet Gynaecol 8 1994 95 116 (Pubitemid 24167047)
20. P. Eftekhari-Yazdi, M.R. Valojerdi, S.K. Ashtiani, M.B. Eslaminejad, and L. Karimian Effect of fragment removal on blastocyst formation and quality of human embryos Reprod BioMed Online 13 2006 823 832 (Pubitemid 46019333)
21. H.J. Chi, J.H. Kim, C.S. Ryu, J.Y. Lee, J.S. Park, and D.Y. Chung Protective effect of antioxidant supplementation in sperm-preparation medium against oxidative stress in human spermatozoa Hum Reprod 23 2008 1023 1028 (Pubitemid 351757326)
22. W. Harrouk, A. Codrington, R. Vinson, B. Robaire, and B.F. Hales Paternal exposure to cyclophosphamide induces DNA damage and alters the expression of DNA repair genes in the rat preimplantation embryo Mutat Res 461 2000 229 241
23. R.G. Sturmey, J.A. Hawkhead, E.A. Barker, and H.J. Leese DNA damage and metabolic activity in the preimplantation embryo Hum Reprod 24 2009 81 91
24. B.A. Stone, J. Greene, J.M. Vargyas, G.E. Ringler, and R.P. Marrs Embryo fragmentation as a determinant of blastocyst development in vitro and pregnancy outcomes following embryo transfer Am J Obstet Gynecol 192 2005 2014 2019
25. M. Takahashi, N. Saka, H. Takahashi, Y. Kanai, R.M. Schultz, and A. Okano Assessment of DNA damage in individual hamster embryos by comet assay Mol Reprod Dev 54 1999 1 7 (Pubitemid 29374841)
26. H. Santhananthan, A. Bonso, S.C. Ng, J. Ho, H. Mok, and S. Ratnam Ultrastructure of preimplantation human embryos co-cultured with human ampullary cells Hum Reprod 5 1990 309 318 (Pubitemid 20253451)
27. M. Johanssom, T. Hardarson, and K. Lundin There is a cutoff limit in diameter between a blastomere and a small anucleate fragment J Assist Reprod Gen 20 2003 309 313 (Pubitemid 37039885)
28. P. Eftekhari-Yazdi, M.R. Valojeri, S.K. Ashtiani, M.B. Eslaminejad, and L. Karimian Effect of fragment removal on blastocyst formation and quality of human embryos Reprod Biomed Online 13 2006 823 832 (Pubitemid 46019333)
29. H.J. Chi, J.J. Koo, J.O. Lee, H.E. Ryu, K.R. Kim, and C. Park Effect of fragment removal on development of human fragmented embryos in IVF-ET program Kor J Reprod Med 37 2010 339 348
30. M. Anrczak, and J. Van Blerkom Temporal and spatial aspects of fragmentation in early human embryos: possible effects on developmental competence and association with the differential elimination of regulatory proteins from polarized domains Hum Reprod 14 1999 429 447 (Pubitemid 29097399)
31. R. Levy, M. Benchaib, H. Cordonier, C. Souchier, and J.F. Guerin Annexin V labeling and terminal transferase-mediated DNA end labeling (TUNEL) assay in human arrested embryos Mol Hum Reprod 4 1998 775 783 (Pubitemid 28392021)
32. D.V. Krysko, T. Vanden Berghe, K. D'Herde, and P. Vandenabeele Apoptosis and necrosis: detection, discrimination and phagocytosis Methods 44 2008 205 221 (Pubitemid 351296447)