Toxoplasma gondii seropositivity and suicide rates in women

Journal of Nervous and Mental Disease

Volumn 199, Issue 7, 2011, Pages 440-444

  Ling, Vinita J ^a   Lester, David ^b   Mortensen, Preben Bo ^c   Langenberg, Patricia W ^d   Postolache, Teodor T ^e  

^a UNIVERSITY OF HAWAII   (United States)

^b RICHARD STOCKTON COLLEGE OF NEW JERSEY   (United States)

^c AARHUS UNIVERSITY   (Denmark)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MARYLAND   (United States)

Author keywords

Europe; suicide; Toxoplasma gondii; Toxoplasmosis

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; DISEASE ASSOCIATION; EUROPE; FEMALE; GENDER; GROUPS BY AGE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MORTALITY; POSTMENOPAUSE; PRESCHOOL CHILD; SCHOOL CHILD; SEROPREVALENCE; SUICIDE; TOXOPLASMOSIS;

ADOLESCENT; ADULT; AGE FACTORS; AGED; CHILD; CHILD, PRESCHOOL; EUROPE; FEMALE; HUMANS; MIDDLE AGED; RISK FACTORS; SOCIOECONOMIC FACTORS; SUICIDE; TOXOPLASMA; TOXOPLASMOSIS; YOUNG ADULT;

EID: 79959907099     PISSN: 00223018     EISSN: 1539736X     Source Type: Journal    
DOI: 10.1097/NMD.0b013e318221416e     Document Type: Article

References (39)

1. Aliberti J (2005) Host persistence: Exploitation of anti-inflammatory pathways by T. gondii. Nat Rev Immunol. 5:162-170. (Pubitemid 40208905)
2. Arling TA, Yolken RH, Lapidus M, Langenberg P, Dickerson FB, Zimmerman SA, Balis T, Cabassa JA, Scrandis DA, Tonelli LH, Postolache TT (2009) Toxoplasma gondii antibody titers and history of suicide attempts in patients with recurrent mood disorders. J Nerv Ment Dis. 197:905-908.
3. Berdoy M, Webster JP, Macdonald DW (2000) Fatal attraction in rats infected with T. gondii. Proc Biol Sci. 267:1591-1594. (Pubitemid 30624132)
4. Capuron L, Schroecksnadel S, Féart C, Aubert A, Higueret D, Barberger-Gateau P, Layé S, Fuchs D (2011) Chronic low-grade inflammation in elderly persons is associated with altered tryptophan and tyrosine metabolism: Role in neuropsychiatric symptoms [published online ahead of print]. Biol Psychiatry.
5. Centers for Disease Control and Prevention (2008) Toxoplasmosis. Division of Parasitic Diseases (DPD) and National Center for Zoonotic, Vector-Borne, and Enteric Diseases (ZVED). Available at: Http://www.cdc.gov/toxoplasmosis/; last reviewed January 10, 2008. Accessed on December 6, 2010.
6. Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW (2008) From inflammation to sickness and depression: When the immune system subjugates the brain. Nat Rev Neurosci. 9:46-56. (Pubitemid 350295688)
7. Dantzer R, O'Connor JC, Lawson MA, KelleyKW (2010) Inflammation- associated depression: From serotonin to kynurenine [published online ahead of print October 30, 2010]. Psychoneuroendocrinology. doi:10.1016/j.psyneuen. 2010.09.012.
8. Delgado PL, Charney DS, Price LH, Aghajanian GK, Landis H, Heniger GR (1990) Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatry. 47:411-418. (Pubitemid 20161259)
9. Denkers EY, Gazzinelli RT (1998) Regulation and function of T-cell-mediated immunity during T. gondii infection. Clin Microbiol Rev. 11:569-588. (Pubitemid 28497562)
10. Flegr J (2007) Effects of Toxoplasma gondii on human behavior. Schizophr Bull. 33:757-760. (Pubitemid 47343712)
11. Flegr J, Kodym P, Tolarová V (2000) Correlation of duration of latent Toxoplasma gondii infection with personality changes in women. Biol Psychol. 53:57-68. (Pubitemid 30389610)
12. Flegr J, Havlicek J, Kodym P, Maly M, Smahel Z (2002) Increased risk of traffic accidents in subjects with latent toxoplasmosis: A retrospective case-control study. BMC Infect Dis. 2:11.
13. Fromont EG, Riche B, Rabilloud M (2009) Toxoplasma gondii seroprevalence in a rural population in France: Detection of a household effect. BMC Infect Dis. 9:76.
14. Havlícek J, Gasová ZG, Smith AP, Zvára K, Flegr J (2001) Decrease of psychomotor performance in subjects with latent 'asymptomatic' toxoplasmosis. Parasitology. 122:515-520. (Pubitemid 32531309)
15. Hawton K, van Heeringen K (2009) Suicide. Lancet. 373:1372-1381.
16. Hinze-Selch D, Däubener W, Erdag, S., Wilms S (2010) The diagnosis of a personality disorder increases the likelihood for seropositivity to Toxoplasma gondii in psychiatric patients. Folia Parasitol. 57:129-135.
17. Hirsch JK (2006) A review of the literature on rural suicide: Risk and protective factors, incidence, and prevention. Crisis 27:189-199.
18. Janelidze S, Mattei D, Westrin Å , Träskman-Bendz L, Brundin L (2011) Cytokine levels in the blood may distinguish suicide attempters from depressed patients [published online ahead of print October 15, 2010]. Brain Behav Immun. 25:335-339.
19. Kar N, Misra B (2004) Toxoplasma seropositivity and depression: A case report. BMC Psychiatry. 4:1.
20. Khabazghazvini B, Groer M, Fuchs D, Strassle P, Lapidus M, Sleemi A, Cabassa JB, Postolache TT (2010) Psychiatric manifestations of latent toxoplasmosis: Potential mediation by indoleamine 2,3-dioxygenase. Int J Disabil Hum Dev. 9:3-10.
21. Lafferty KD (2006) Can the common brain parasite, Toxoplasma gondii, influence human culture? Proc Biol Sci. 273:2749-2755. (Pubitemid 44671919)
22. Lester, D (2010) Brain parasites and suicide. Psychol Rep. 107:424.
23. Lindová J, Novotná M, Havlícek J, Jozífková E, Skallová A, Kolbeková P, Hodn] Z, Kodym P, Flegr J (2006) Gender differences in behavioural changes induced by latent toxoplasmosis. Int J Parasitol. 36:1485-1492. (Pubitemid 44751745)
24. Lindqvist D, Janelidze S, Hagell P, Erhardt S, Samuelsson M, Minthon L, Hansson O, Björkqvist M, Träskman-Bendz L, Brundin L (2009) Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity. Biol Psychiatry. 66:287-292.
25. Lindqvist D (2010) Refining suicidal behavior: Rating scales and biomarkers (pp 62-63). Lund, Sweden: University Press.
26. McCloskey MS, Ben-Zeev D, Lee R, Berman ME, Coccaro EF (2009) Acute tryptophan depletion and self-injurious behavior in aggressive patients and healthy volunteers. Psychopharmacology (Berl). 203:53-61.
27. Miller CM, Boulter NR, Ikin RJ, Smith NC (2009) The immunobiology of the innate response to T. gondii. Int J Parasitol. 39:23-39.
28. Montoya JG, Liesenfeld O (2004) Toxoplasmosis. Lancet. 363:1965-1976. (Pubitemid 38759657)
29. Russo S, Kema IP, Haagsma EB, Boon JC, Willemse PH, den Boer JA, de Vries EG, Korf J (2005) Irritability rather than depression during interferon treatment is linked to increased tryptophan catabolism. Psychosom Med. 67:773-777. (Pubitemid 41396025)
30. Sublette ME, Galfalvy HC, Fuchs D, Lapidus M, Grunebaum M, Oquendo MA, Mann JJ, Postolache TT (2011) Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder. Abstract accepted for presentation to: 66th Annual Meeting of the Society for Biological Psychiatry; San Francisco, CA; 2011.
31. Tenter AM, Heckeroth AR, Weiss LM (2000) T. gondii: From animals to humans. Int J Parasitol. 30:1217-1258.
32. Torrey EF, Bartko JJ, Lun ZR, Yolken RH (2007) Antibodies to T. gondii in patients with schizophrenia: A meta-analysis. Schizophr Bull. 33:729-736. (Pubitemid 47343710)
33. Vyas A, Kim SK, Giacomini N, Boothroyd JC, Sapolsky RM (2007) Behavioral changes induced by T. gondii infection of rodents are highly specific to aversion of cat odors. Proc Natl Acad Sci. 104:6442-6447. (Pubitemid 47186113)
34. Webster JP (2007) The effect of T. gondii on animal behavior: Playing cat and mouse. Schizophr Bull. 33:752-756. (Pubitemid 47343711)
35. Wonodi I, Schwarcz R (2010) Cortical kynurenine pathway metabolism: A novel target for cognitive enhancement in schizophrenia [published online ahead of print February 10, 2010]. Schizophr Bull. doi:10.1093/schbul/sbq002.
36. World Bank (2010) GDP per capita (current US$) | Data | Indicators | Table. World Bank, Available at: Http://data.worldbank.org/indicator/NY.GDP. PCAP.CD? page=3. Accessed December 1, 2010.
37. World Health Organization (2010) European Mortality Database (MDB). Available at: Http://data.euro.who.int/hfamdb/. Accessed on December 6, 2010.
38. Yagmur F, Yazar S, Temel HO, Cavusoglu M (2010). May Toxoplasma gondii increase suicide attempt-preliminary results in Turkish subjects? Forensic Sci Int. 199:1-3.
39. Yereli K, Balcioǧlu IC, Ozbilgin A (2006) Is T. gondii a potential risk for traffic accidents in Turkey? Forensic Sci Int. 163:34-37. (Pubitemid 44442794)