Isatis indigotica induces hepatocellular cancer cell death via caspase-independent apoptosis-inducing factor translocation apoptotic pathway in vitro and in vivo

Integrative Cancer Therapies

Volumn 10, Issue 2, 2011, Pages 201-214

  Chung, Ying Cheng ^a   Tang, Feng Yao ^b   Liao, Jiunn Wang ^a   Chung, Chia Hua ^a   Jong, Ting Ting ^a   Chen, Shih Shiung ^a   Tsai, Ching Hsiu ^a   Chiang, En Pei ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

antiproliferation; apoptosis inducing factor; caspase independent apoptotic pathway; cell cycle arrest; tumor growth inhibition

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; CASPASE; CHLOROFORM; HERBACEOUS AGENT; ISATIS INDIGOTICA LEAF EXTRACT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL STRESS; CONTROLLED STUDY; CYTOSOL; FEMALE; HEPATOMA CELL; ISATIS; ISATIS INDIGOTICA; LIVER CELL CARCINOMA; MEDICINAL PLANT; MITOCHONDRION; MOUSE; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BODY WEIGHT; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 9; CASPASES; CELL CYCLE; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; DRUGS, CHINESE HERBAL; EATING; FEMALE; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; ISATIS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; ORGAN SIZE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79959786197     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735410387420     Document Type: Article

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