Identification of Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) as a CD8+ T-cell-defined human tumor antigen of human carcinomas

Cancer Immunology, Immunotherapy

Volumn 60, Issue 7, 2011, Pages 919-929

  Visus, Carmen ^a,b   Ito, Diasuke ^a,b   Dhir, Rajiv ^a,b   Szczepanski, Miroslaw J ^a,b   Chang, Yoo Jung ^a   Latimer, Jean J ^a,b   Grant, Stephen G ^a,c   Deleo, Albert B ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

CTL; Head and neck cancer; HSD17B12; Tumor antigen

Indexed keywords

ARACHIDONIC ACID; EPITOPE; ESTRADIOL; GAMMA INTERFERON; HLA A2 ANTIGEN; ISOLEUCYLTYROSYLASPARTYLLYSYLISOLEUCYLLYSYLTHREONYLGLYCYLLEUCINE; PEPTIDE; TESTOSTERONE 17BETA DEHYDROGENASE; TESTOSTERONE 17BETA DEHYDROGENASE 12; THREONINE; THREONYLTYROSYLASPARTYLLYSYLISOLEUCYLLYSYLTHREONYLGLYCYLLEUCINE; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CLINICAL ARTICLE; CROSS REACTION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; GROWTH INHIBITION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; IMMUNOGENICITY; IN VITRO STUDY; MALE; PEPTIDE ANALYSIS; PRIORITY JOURNAL; RESIDUE ANALYSIS;

17-HYDROXYSTEROID DEHYDROGENASES; ADULT; AGED; ANTIGENS, NEOPLASM; BREAST; BREAST NEOPLASMS; CARCINOMA, SQUAMOUS CELL; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES, T-LYMPHOCYTE; FEMALE; FIBROBLASTS; HEAD AND NECK NEOPLASMS; HLA-A2 ANTIGEN; HUMANS; IMMUNOENZYME TECHNIQUES; INTERFERON-GAMMA; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; T-LYMPHOCYTES, CYTOTOXIC;

EID: 79959770703     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-011-1001-y     Document Type: Article

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