A hind limb disuse model inducing extensor digitorum longus atrophy in rats: Tail suspension-immobilization

Aviation Space and Environmental Medicine

Volumn 82, Issue 7, 2011, Pages 689-693

  Du, Fangying ^a   Wang, Jun ^a,b   Gao, Yunfang ^a,c   Wang, Huiping ^a   Wang, Qi ^a,c   Jiang, Shanfeng ^a   Goswami, Nandu ^d  

^a NORTHWEST UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c SHAANXI UNIVERSITY OF TECHNOLOGY   (China)

^d MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Disuse atrophy; Immobilization; Muscle fibre type; Skeletal muscle morphology change; Tail suspension

Indexed keywords

ANIMAL; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; FAST MUSCLE FIBER; FEMALE; IMMOBILIZATION; METHODOLOGY; MUSCLE ATROPHY; PATHOLOGY; RAT; SKELETAL MUSCLE; SLOW MUSCLE FIBER; SPRAGUE DAWLEY RAT;

ANIMALS; FEMALE; HINDLIMB SUSPENSION; MODELS, ANIMAL; MUSCLE FIBERS, FAST-TWITCH; MUSCLE FIBERS, SKELETAL; MUSCLE FIBERS, SLOW-TWITCH; MUSCULAR ATROPHY; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; RATTUS;

EID: 79959765176     PISSN: 00956562     EISSN: None     Source Type: Journal    
DOI: 10.3357/ASEM.2984.2011     Document Type: Article

References (21)

1. Adams GR, Caiozzo VJ, Baldwin KM. Skeletal muscle unweighting: spaceflight and ground-based models. J Appl Physiol 2003; 95: 2185-201.
2. Aryan FA, Alnaqeeb MA. Effect of immobilization and underload on skeletal muscle in the hindlimb of the Jerboa. Kuwait Journal of Science and Engineering 2002; 29: 83-97.
3. Mokhtarian A, Lefaucheur JP, Even PC, Sebille A. Hindlimb immobilization applied to 21-day-old mdx mice prevents the occurrence of muscle degeneration. J Appl Physiol 1999; 86: 924-31.
4. Asmussen G, Soukup T. Arrest of developmental conversion of type II to type I fibres after suspension hypokinesia. Histochem J 1991; 23: 312-22.
5. Banzet S, Koulmann N, Sanchez H, Serrurier B, Peinnequin A, Bigard AX. Musclin gene expression is strongly related to fastglycolytic phenotype. Biochem Biophys Res Commun 2007; 353: 713-8.
6. Bigard AX, Boehm E, Veksler V, Mateo P, Anflous K, Ventura-Clapier R. Muscle unloading induces slow to fast transitions in myofibrillar but not mitochondrial properties. Relevance to skeletal muscle abnormalities in heart failure. J Mol Cell Cardiol 1998; 30: 2391-401.
7. Blottner D, Serradj N, Salanova M, Touma C, Palme R, et al. Morphological, physiological and behavioural evaluation of a ' Mice in Space ' housing system. J Comp Physiol B 2009; 179: 519-33.
8. Desplanches D, Mayet MH, Ilyina-Kakueva EI, Sempore B, Flandrois R. Skeletal muscle adaptation in rats flown on Cosmos 1667. J Appl Physiol 1990; 68: 48-52.
9. Desplanches D, Mayet MH, Sempore B, Flandrois R. Structural and functional responses to prolonged hindlimb suspension in rat muscle. J Appl Physiol 1987; 63: 558-63.
10. Dubowitz V, Brooke MH. 1973 Muscle biopsy: a modern approach London: WB Saunders Co Ltd 20-33.
11. Fitts RH, Rilley DR, Widrick JJ. Functional and structural adaptations of skeletal muscle to microgravity. J Exp Biol 2001; 204: 3201-8.
12. Giroux-Metges MA, Pennec JP, Petit J, Morel J, Talarmin H, et al. Effects of immobilizing a single muscle on the morphology and the activation of its muscle fibers. Exp Neurol 2005; 194: 495-505.
13. Guillot C, Steinberg JG, Delliaux S, Kipson N, Jammes Y, Badier M. Physiological, histological and biochemical properties of rat skeletal muscles in response to hindlimb suspension. J Electromyogr Kinesiol 2008; 18: 276-83.
14. Kourtidou-Papadeli C, Kyparos A, Albani M, Frossinis A, Papadelis CL, et al. Electrophysiological, histochemical, and hormonal adaptation of rat muscle after prolonged hindlimb suspension. Acta Astronaut 2004; 54: 737-47.
15. Morey ER. Spaceflight and bone turnover: correlation with a new rat model of weightlessness. Bioscience 1979; 29: 168-72.
16. 2+ activation properties in human muscle fibers: effects of a 60-day bed rest and countermeasures. J Appl Physiol 2009; 106: 1086-99.
17. Salanova M, Schiffl G, Püttmann B, Schoser BG, Blottner D. Molecular biomarkers monitoring human skeletal muscle fibres and microvasculature following long-term bed rest with and without countermeasures. J Anat 2008; 212: 306-18.
18. Soukup T, Zacharová G, Smerdu V. Fibre type composition of soleus and extensor digitorum longus muscles in normal female inbred Lewis rats. Acta Histochem 2002; 104: 399-405.
19. Stevens L, Firinga C, Gohlsch B, Bastide B, Mounier Y, Pette D. Effects of unweighting and clenbuterol on myosin light and heavy chains in fast and slow muscles of rat. Am J Physiol Cell Physiol 2000; 279: C1558-63.
20. Vesely MJJ, Sanders R, Green CJ, Motterlini R. Fibre type specificity of haem oxygenase-1 induction in rat skeletal muscle. FEBS Lett 1999; 458: 257-60.
21. Williams D, Kuipers A, Mukai C, Thirsk R. Acclimation during space fl ight: effects on human physiology. CMAJ 2009; 180: 1317-23.