Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics

Proteomics

Volumn 11, Issue 14, 2011, Pages 2763-2776

  Jing, Linhong ^a,b   Parker, Carol E ^a,c   Seo, David ^d,e   Hines, Maria Warren ^a   Dicheva, Nedyalka ^a   Yu, Yanbao ^c   Schwinn, Debra ^f   Ginsburg, Geoffrey S ^d   Chen, Xian ^a,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b SOUTH DAKOTA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d Institute for Genomic Sciences and Policy   (United States)

^e UNIVERSITY OF MIAMI   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Animal proteomics; Biomarker discovery; Coronary artery disease; Expression profiling; Liquid chromatography tandem mass spectrometry; Quantitative analysis

Indexed keywords

ALPHA 1 ANTITRYPSIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN B; APOLIPOPROTEIN C1; APOLIPOPROTEIN C2; APOLIPOPROTEIN C3; APOLIPOPROTEIN D; APOLIPOPROTEIN E; BIOLOGICAL MARKER; CARBONATE DEHYDRATASE II; CLUSTERIN; COMPLEMENT COMPONENT C9; COMPLEMENT FACTOR D; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRINOGEN; FIBRINOGEN BETA; FIBRINOGEN GAMMA; GELSOLIN; HAPTOGLOBIN; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN BETA CHAIN; HEMOPEXIN; LACTOFERRIN; PEROXIREDOXIN 2; PROPERDIN; PROTHROMBIN; SELENOPROTEIN P; SERUM AMYLOID P; THROMBOSPONDIN 4; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CORONARY ARTERY DISEASE; DOWN REGULATION; ELECTROSPRAY MASS SPECTROMETRY; KNOCKOUT MOUSE; LIPID DIET; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEOMICS; REVERSED PHASE LIQUID CHROMATOGRAPHY; UNINDEXED SEQUENCE; UPREGULATION; WILD TYPE;

ADULT; ANIMALS; APOLIPOPROTEINS E; BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ANIMALIA; MUS;

EID: 79959757195     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000202     Document Type: Article

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