A natural inactivating mutant of human glucagon receptor exhibits multiple abnormalities in processing and signaling

Endocrinologia y Nutricion

Volumn 58, Issue 6, 2011, Pages 258-266

  Yu, Run ^a   Wawrowsky, Kolja ^a   Zhou, Cuiqi ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Mutant glucagon receptor; Processing; Signaling

Indexed keywords

CALCIUM; G PROTEIN COUPLED RECEPTOR; GLUCAGON; GLUCAGON RECEPTOR; MUTANT PROTEIN; PROTEASOME INHIBITOR; RHODOPSIN; THAPSIGARGIN; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CELL FATE; CELL MEMBRANE; CELL SURVIVAL; CYTOPLASM; ENDOCRINE DISEASE; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MAHVASH DISEASE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

APOPTOSIS; CALCIUM SIGNALING; CELL LINE; CELL MEMBRANE; CYCLIC AMP; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; GLUCAGON; GLUCAGON-SECRETING CELLS; HUMANS; HYPERPLASIA; HYPOGLYCEMIA; MUTATION, MISSENSE; NEOPLASTIC SYNDROMES, HEREDITARY; NEUROENDOCRINE TUMORS; PANCREATIC NEOPLASMS; POINT MUTATION; RECEPTORS, GLUCAGON; RECOMBINANT FUSION PROTEINS;

EID: 79959741674     PISSN: 15750922     EISSN: 15792021     Source Type: Journal    
DOI: 10.1016/j.endonu.2011.04.002     Document Type: Article

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