Jatrophane diterpenes from euphorbia esula as antiproliferative agents and potent chemosensitizers to overcome multidrug resistance

Journal of Natural Products

Volumn 74, Issue 6, 2011, Pages 1453-1461

  Vasas, Andrea ^a   Sulyok, Edvárd ^a   Rédei, Dóra ^a   Forgo, Peter ^a   Szabó, Pál ^b   Zupkó, István ^a   Berényi, Ágnes ^a   Molnár, Joseph ^a   Hohmann, Judit ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

^b CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

2ALPHA,3BETA,5ALPHA,7BETA,15BETA PENTAACETOXY 9ALPHA NICOTINOYLOXYJATROPHA 6(17),11 DIEN 14 ONE; ANTINEOPLASTIC AGENT; CISPLATIN; DITERPENE; ESULATIN A; ESULATIN B; ESULATIN C; ESULATIN D; ESULATIN E; ESULATIN F; ESULATIN H; ESULATIN I; ESULATIN J; ESULATIN K; ESULATIN L; ESULATIN M; EUPHOSALICIN; JATROPHANE DITERPENE DERIVATIVE; SALICINOLIDE; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; EUPHORBIA; EUPHORBIA ESULA; HELA CELL; HUMAN; HUMAN CELL; IC 50; LYMPHOMA CELL; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DITERPENES; DRUG RESISTANCE, MULTIPLE; EUPHORBIA; FEMALE; HELA CELLS; HUMANS; HUNGARY; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EUPHORBIA ESULA;

EID: 79959734124     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np200202h     Document Type: Article

References (33)

1. Baloch, I. B.; Baloch, M. K. J. Asian Nat. Prod. Res. 2010, 12, 600-613
2. Lage, H.; Duarte, N.; Coburger, C.; Hilgeroth, A.; Ferreira, M. J. Phytomedicine 2010, 17, 441-448
3. Wang, H. B.; Chu, W. J.; Wang, Y.; Ji, P.; Wang, Y. B.; Yu, Q.; Qin, G. W. J. Asian Nat. Prod. Res. 2010, 12, 1038-1043
4. Hegazy, M. E.; Mohamed, A. H.; Aoki, N.; Ikeuchi, T.; Ohta, E.; Ohta, S. Phytochemistry 2010, 71, 249-253
5. Hergenhahn, M.; Kusumoto, S.; Hecker, E. J. Cancer Res. Clin. Oncol. 1984, 108, 98-109
6. Mucsi, I.; Molnár, J.; Hohmann, J.; Rédei, D. Planta Med. 2001, 67, 672-674
7. Hasler, C. M.; Acs, G.; Blumberg, P. Cancer Res. 1992, 52, 202
8. Shizuri, Y.; Kosemura, S.; Ohtsuka, J.; Terada, Y.; Yamamura, S.; Ohba, S.; Ito, M.; Saito, Y. Tetrahedron Lett. 1984, 25, 1155-1158
9. Roengsumran, S.; Singtothong, P.; Pudhom, K.; Ngamrochanavanich, N.; Petsom, A.; Chaichantipyuth, C. J. Nat. Prod. 1999, 62, 1163-1164
10. Xu, Z. H.; Sun, J.; Xu, R. S.; Qui, G. W. Phytochemistry 1998, 49, 149-151
11. Miranda, F. J.; Alabadí, J. A.; Ortí, M.; Centeno, J. M.; Pinón, M.; Yuste, A.; Sanz-Cervera, J. F.; Marco, J. A.; Alborch, E. J. Pharm. Pharmacol. 1998, 50, 237-241
12. Liu, L. G.; Meng, J. C.; Wu, S. X.; Li, X. Y.; Zhao, X. C.; Tan, R. X. Planta Med. 2002, 68, 244-248
13. Lu, Z. Q.; Guan, S. H.; Li, X. N.; Chen, G. T.; Zhang, J. Q.; Huang, H. L.; Liu, X.; Guo, D. A. J. Nat. Prod. 2008, 71, 873-876
14. Duarte, N.; Lage, H.; Ferreira, M. J. U. Planta Med. 2008, 74, 61-68
15. Miglietta, A.; Gabriel, L.; Appendino, G.; Bocca, C. Cancer Chemother. Pharm. 2003, 51, 67-74
16. Hohmann, J.; Molnár, J.; Rédei, D.; Evanics, F.; Forgo, P.; Kálmán, A.; Argay, G.; Szabó, P. J. Med. Chem. 2002, 45, 2425-2431
17. Duarte, N.; Járdánházy, A.; Molnár, J.; Hilgeroth, A.; Ferreira, M. J. U. Bioorg. Med. Chem. 2008, 16, 9323-9330
18. Corea, G.; Di Pietro, A; Dumontet, C.; Fattorusso, E.; Lanzotti, V. Phytochem. Rev. 2009, 8, 431-447
19. Lu, Z. Q.; Yang, M.; Zhang, J. Q.; Chen, G. T.; Huang, H. L.; Guan, S. H.; Ma, C.; Liu, X.; Guo, D. A. Phytochemistry 2008, 69, 812-819
20. Onwukaeme, N. D.; Rowan, M. G. Phytochemistry 1992, 31, 3479-3482
21. Sekine, T.; Kamiya, M.; Ikegami, F.; Qi, J. F. Nat. Prod. Lett. 1998, 12, 237-239
22. Kupchan, S. M.; Uchida, I.; Branfman, A. R.; Dailey, R. G.; Fei, B. Y. Science 1976, 191, 571-572
23. Valente, C.; Pedro, M.; Duarte, A.; Nascimento, M. S.; Abreu, P. M.; Ferreira, M. J. J. Nat. Prod. 2004, 67, 902-904
24. Engi, H.; Vasas, A.; Rédei, D.; Molnár, J.; Hohmann, J. Anticancer Res. 2007, 27, 3454-3458
25. Hohmann, J.; Vasas, A.; Günther, G.; Máthé, I.; Evanics, F.; Dombi, G.; Jerkovich, G. J. Nat. Prod. 1997, 60, 331-335
26. Günther, G.; Hohmann, J.; Vasas, A.; Máthé, I.; Dombi, G.; Jerkovich, G. Phytochemistry 1998, 47, 1309-1313
27. Günther, G.; Martinek, T.; Dombi, G.; Hohmann, J.; Vasas, A. Magn. Reson. Chem. 1999, 37, 365-370
28. Jakupovic, J.; Morgenstern, T.; Bittner, M.; Silva, M. Phytochemistry 1998, 47, 1601-1609
29. Hohmann, J.; Evanics, F.; Berta, L.; Bartók, T. Planta Med. 2000, 66, 291-294
30. Hohmann J.; Evanics, F.; Dombi, G.; Szabó, P. Tetrahedron Lett. 2001, 42, 6581-6584
31. Hohmann, J.; Evanics, F.; Dombi, G.; Molnár, J.; Szabó, P. Tetrahedron 2001, 57, 211-215
32. Mossmann, T. J. Immunol. Methods 1983, 65, 55-63
33. Cornwell, M. M.; Pastan, I.; Gottesmann, M. M. J. Biol. Chem. 1987, 262, 2166-2170