Peripheral nerve defect repair with epineural tubes supported with bone marrow stromal cells: A preliminary report

Annals of Plastic Surgery

Volumn 67, Issue 1, 2011, Pages 73-84

  Siemionow, Maria ^a   Duggan, William ^a   Brzezicki, Grzegorz ^a   Klimczak, Aleksandra ^a   Grykien, Christopher ^a   Gatherwright, James ^a   Nair, Dileep ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

autograft repair; bone marrow stromal cells (BMSC); epineural tube; nerve growth factors; peripheral nerve repair

Indexed keywords

NERVE GROWTH FACTOR;

ANIMAL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; GRAFT SURVIVAL; INJURY; ISOGRAFT; LEWIS RAT; MALE; METABOLISM; METHODOLOGY; NERVE REGENERATION; PHYSIOLOGY; PLASTIC SURGERY; RAT; SCIATIC NERVE; STROMA CELL; TRANSPLANTATION;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; GRAFT SURVIVAL; MALE; NERVE GROWTH FACTORS; NERVE REGENERATION; RATS; RATS, INBRED LEW; RECONSTRUCTIVE SURGICAL PROCEDURES; SCIATIC NERVE; STROMAL CELLS; TRANSPLANTATION, ISOGENEIC;

EID: 79959711156     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/SAP.0b013e318223c2db     Document Type: Conference Paper

References (60)

1. Masaki T, Matsumura K, Saito F, et al. Association of dystroglycan and laminin-2 coexpression with myelinogenesis in peripheral nerves. Med Electron Microsc. 2003;36:221-239. (Pubitemid 38133229)
2. Millesi H. Nerve grafts: indication, techniques, and prognoses. In: Omer GE, Spinner M, Van Beek AL, eds. Management of Peripheral Nerve Problems. Philadelphia, PA: W. B. Saunders; 1998:280-289.
3. Strauch B. Use of nerve conduits in peripheral nerve repair. Hand Clin. 2000;16:123-130. (Pubitemid 30117168)
4. Meirer R, Babuccu O, Unsal M, et al. Effect of chronic cyclosporine administration on peripheral nerve regeneration: a dose-response study. Ann Plast Surg. 2002;49:96-103. (Pubitemid 34755474)
5. Siemionow M, Tetik C, Ozer K, et al. Epineural sleeve neurorrhaphy: surgical technique and functional results-a preliminary report. Ann Plast Surg. 2002; 48:281-285. (Pubitemid 34205139)
6. Tetik C, Ozer K, Ayhan S, et al. Conventional versus epineural sleeve neurorrhaphy technique: functional and histomorphometric analysis. Ann Plast Surg. 2002;49:397-403.
7. Scharpf J, Meirer R, Zielinski M, et al. A novel technique for peripheral nerve repair. Laryngoscope. 2003;113:95-101. (Pubitemid 36050521)
8. Lubiatowski P, Unsal FM, Nair D, et al. The epineural sleeve technique for nerve graft reconstruction enhances nerve recovery. Microsurgery. 2008;28: 160-167. (Pubitemid 351458262)
9. Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci USA. 1999;96: 10711-10716. (Pubitemid 29442209)
10. Kim HA, Ratner N, Roberts TM, et al. Schwann cell proliferative responses to cAMP and Nf1 are mediated by cyclin D1. J Neurosci. 2001;21:1110-1116. (Pubitemid 32128756)
11. Sanchez-Ramos J, Song S, Cardozo-Pelaez F, et al. Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol. 2000;164: 247-256. (Pubitemid 32008970)
12. Dezawa M, Adachi-Usami E. Role of Schwann cells in retinal ganglion cell axon regeneration. Prog Retin Eye Res. 2000;19:171-204.
13. Chopp M, Zhang XH, Li Y, et al. Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. Neuroreport. 2000;11:3001-3005.
14. Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science. 1997;276:71-74. (Pubitemid 27161245)
15. LeBeau JM, Liuzzi FJ, Depto AS, et al. Differential laminin gene expression in dorsal root ganglion neurons and nonneuronal cells. Exp Neurol. 1994; 127:1-8. (Pubitemid 24199217)
16. Tucker BA, Rahimtula M, Mearow KM. Integrin activation and neurotrophin signaling cooperate to enhance neurite outgrowth in sensory neurons. J Comp Neurol. 2005;486:267-280. (Pubitemid 40593959)
17. Rosenstein JM, Krum JM. New roles for VEGF in nervous tissue-beyond blood vessels. Exp Neurol. 2004;187:246-253. (Pubitemid 38610271)
18. Sondell M, Lundborg G, Kanje M. Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J Neurosci. 1999;19:5731-5740. (Pubitemid 29327910)
19. Sondell M, Sundler F, Kanje M. Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk-1 receptor. Eur J Neurosci. 2000;12:4243-4254. (Pubitemid 32037835)
20. Snyder CC. Epineurial repair. Orthop Clin North Am. 1981;12:267-276. (Pubitemid 11037446)
21. Ignatiadis IA, Tsiampa VA, Yiannakopoulos CK, et al. A new technique of autogenous conduits for bridging short nerve defects. An experimental study in the rabbit. Acta Neurochir Suppl. 2007;100:73-76.
22. Ignatiadis IA, Yiannakopoulos CK, Barbitsioti AD, et al. Diverse types of epineural conduits for bridging short nerve defects. An experimental study in the rabbit. Microsurgery. 2007;27:98-104. (Pubitemid 46411435)
23. Karacaoglu E, Yuksel F, Peker F, et al. Nerve regeneration through an epineurial sheath: its functional aspect compared with nerve and vein grafts. Microsurgery. 2001;21:196-201. (Pubitemid 33086096)
24. Ignatiadis IA, Yiannakopoulos CK, Avram AM, et al. Posttraumatic neuroma of the radial nerve treated with an autogenous epineural conduit technique. A case report. Microsurgery. 2009;29:133-135.
25. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143-147. (Pubitemid 29282067)
26. Chen CJ, Ou YC, Liao SL, et al. Transplantation of bone marrow stromal cells for peripheral nerve repair. Exp Neurol. 2007;204:443-453.
27. Dezawa M, Takahashi I, Esaki M, et al. Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells. Eur J Neurosci. 2001;14:1771-1776. (Pubitemid 35463694)
28. Myckatyn TM, Mackinnon SE. A review of research endeavors to optimize peripheral nerve reconstruction. Neurol Res. 2004;26:124-138. (Pubitemid 38419095)
29. Fawcett JW, Keynes RJ. Muscle basal lamina: a new graft material for peripheral nerve repair. J Neurosurg. 1986;65:354-363. (Pubitemid 16042442)
30. Kim DH, Connolly SE, Zhao S, et al. Comparison of macropore, semipermeable, and nonpermeable collagen conduits in nerve repair. J Reconstr Microsurg. 1993;9:415-420. (Pubitemid 23345614)
31. Evans PJ, Midha R, Mackinnon SE. The peripheral nerve allograft: a comprehensive review of regeneration and neuroimmunology. Prog Neurobiol. 1994;43:187-233. (Pubitemid 24269533)
32. Navarro X, Rodriguez FJ, Labrador RO, et al. Peripheral nerve regeneration through bioresorbable and durable nerve guides. J Peripher Nerv Syst. 1996;1:53-64. (Pubitemid 126674021)
33. Fansa H, Keilhoff G. Comparison of different biogenic matrices seeded with cultured Schwann cells for bridging peripheral nerve defects. Neurol Res. 2004;26:167-173. (Pubitemid 38419100)
34. Bunge RP. Expanding roles for the Schwann cell: ensheathment, myelination, trophism and regeneration. Curr Opin Neurobiol. 1993;3:805-809. (Pubitemid 23303389)
35. Hori J, Ng TF, Shatos M, et al. Neural progenitor cells lack immunogenicity and resist destruction as allografts. Stem Cells. 2003;21:405-416. (Pubitemid 36798086)
36. Hori J, Ng TF, Shatos M, et al. Neural progenitor cells lack immunogenicity and resist destruction as allografts. 2003. Ocul Immunol Inflamm. 2007;15: 261-273.
37. Zhang P, He X, Zhao F, et al. Bridging small-gap peripheral nerve defects using biodegradable chitin conduits with cultured Schwann and bone marrow stromal cells in rats. J Reconstr Microsurg. 2005;21:565-571. (Pubitemid 41742204)
38. Pereira Lopes FR, Camargo de Moura Campos L, Dias Correa J Jr, et al. Bone marrow stromal cells and resorbable collagen guidance tubes enhance sciatic nerve regeneration in mice. Exp Neurol. 2006;198:457-468.
39. Chen X, Wang XD, Chen G, et al. Study of in vivo differentiation of rat bone marrow stromal cells into Schwann cell-like cells. Microsurgery. 2006;26: 111-115.
40. Novikova LN, Mosahebi A, Wiberg M, et al. Alginate hydrogel and matrigel as potential cell carriers for neurotransplantation. J Biomed Mater Res A. 2006;77:242-252. (Pubitemid 47233525)
41. Yamakawa T, Kakinoki R, Ikeguchi R, et al. Nerve regeneration promoted in a tube with vascularity containing bone marrow-derived cells. Cell Transplant. 2007;16:811-822. (Pubitemid 351448257)
42. Hou SY, Zhang HY, Quan DP, et al. Tissue-engineered peripheral nerve grafting by differentiated bone marrow stromal cells. Neuroscience. 2006; 140:101-110.
43. Nie X, Zhang YJ, Tian WD, et al. Improvement of peripheral nerve regeneration by a tissue-engineered nerve filled with ectomesenchymal stem cells. Int J Oral Maxillofac Surg. 2007;36:32-38. (Pubitemid 46029854)
44. Zhang P, Xu H, Zhang D, et al. The biocompatibility research of functional Schwann cells induced from bone mesenchymal cells with chitosan conduit membrane. Artif Cells Blood Substit Immobil Biotechnol. 2006;34:89-97.
45. Mimura T, Dezawa M, Kanno H, et al. Peripheral nerve regeneration by transplantation of bone marrow stromal cell-derived Schwann cells in adult rats. J Neurosurg. 2004;101:806-812. (Pubitemid 39430974)
46. Tohill M, Mantovani C, Wiberg M, et al. Rat bone marrow mesenchymal stem cells express glial markers and stimulate nerve regeneration. Neurosci Lett. 2004;362:200-203. (Pubitemid 38648941)
47. Shimizu S, Kitada M, Ishikawa H, et al. Peripheral nerve regeneration by the in vitro differentiated-human bone marrow stromal cells with Schwann cell property. Biochem Biophys Res Commun. 2007;359:915-920. (Pubitemid 46946904)
48. Keilhoff G, Goihl A, Langnase K, et al. Transdifferentiation of mesenchymal stem cells into Schwann cell-like myelinating cells. Eur J Cell Biol. 2006; 85:11-24. (Pubitemid 43055554)
49. Keilhoff G, Goihl A, Stang F, et al. Peripheral nerve tissue engineering: autologous Schwann cells vs. transdifferentiated mesenchymal stem cells. Tissue Eng. 2006;12:1451-1465. (Pubitemid 44174781)
50. Keilhoff G, Stang F, Goihl A, et al. Transdifferentiated mesenchymal stem cells as alternative therapy in supporting nerve regeneration and myelination. Cell Mol Neurobiol. 2006;26:1235-1252. (Pubitemid 44924044)
51. Li N, Yang H, Lu L, et al. Spontaneous expression of neural phenotype and NGF, TrkA, TrkB genes in marrow stromal cells. Biochem Biophys Res Commun. 2007;356:561-568. (Pubitemid 46509763)
52. Calza L, Giardino L, Giuliani A, et al. Nerve growth factor control of neuronal expression of angiogenetic and vasoactive factors. Proc Natl Acad Sci USA. 2001;98:4160-4165. (Pubitemid 32249915)
53. Krum JM, Rosenstein JM. VEGF mRNA and its receptor flt-1 are expressed in reactive astrocytes following neural grafting and tumor cell implantation in the adult CNS. Exp Neurol. 1998;154:57-65. (Pubitemid 28553567)
54. Bartholdi D, Rubin BP, Schwab ME. VEGF mRNA induction correlates with changes in the vascular architecture upon spinal cord damage in the rat. Eur J Neurosci. 1997;9:2549-2560. (Pubitemid 28082944)
55. Fu CY, Hong GX, Wang FB. Expression of vascular endothelial growth factor and its fetal liver kinase-1 receptor in spinal cord and dorsal root ganglia after neurotomy of sciatic nerve in rats. Chin J Traumatol. 2005;8: 17-22.
56. Hobson MI, Brown R, Green CJ, et al. Inter-relationships between angiogenesis and nerve regeneration: a histochemical study. Br J Plast Surg. 1997; 50:125-131. (Pubitemid 27107462)
57. Fernandes M, Valente SG, Fernandes MJ, et al. Bone marrow cells are able to increase vessels number during repair of sciatic nerve lesion. J Neurosci Methods. 2008;170:16-24.
58. Choi BH, Zhu SJ, Kim BY, et al. Transplantation of cultured bone marrow stromal cells to improve peripheral nerve regeneration. Int J Oral Maxillofac Surg. 2005;34:537-542.
59. Wiberg M, Terenghi G. Will it be possible to produce peripheral nerves? Surg Technol Int. 2003;11:303-310.
60. Ffrench-Constant C, Colognato H, Franklin RJ. Neuroscience. The mysteries of myelin unwrapped. Science. 2004;304:688-689.