A novel optical method to assess cervical changes during pregnancy and use to evaluate the effects of progestins on term and preterm labor

American Journal of Obstetrics and Gynecology

Volumn 205, Issue 1, 2011, Pages 82.e15-82.e20

  Kuon, Ruben J ^b   Shi, Shao Qing ^a   Maul, Holger ^b   Sohn, Christof ^b   Balducci, James ^a   Shi, Leili ^a   Garfield, Robert E ^a  

^a ST JOSEPH'S HOSPITAL AND MEDICAL CENTER   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

17 alpha hydroxyprogesterone caproate; cervix; preterm labor; progesterone; rat

Indexed keywords

HYDROXYPROGESTERONE CAPROATE; MIFEPRISTONE; PROGESTERONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DELIVERY; DRUG EFFECT; ENDOSCOPY; FEMALE; FLUORESCENCE; LABOR; MEDICAL PHOTOGRAPHY; METHODOLOGY; NONHUMAN; OPTICAL EVALUATION; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; RAT; UTERINE CERVIX; UTERINE CERVIX RIPENING;

EID: 79959690714     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2011.02.048     Document Type: Article

References (43)

1. S. Beck, D. Wojdyla, and L. Say The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity Bull World Health Organ 88 2010 31 38
2. P. Steer The epidemiology of preterm labour BJOG 112 suppl 1 2005 1 3 (Pubitemid 40313972)
3. R.E. Garfield, W.L. Maner, H. Maul, and G.R. Saade Use of uterine EMG and cervical LIF in monitoring pregnant patients BJOG 112 suppl 1 2005 103 108 (Pubitemid 40313993)
4. N. Uldbjerg, G. Ekman, A. Malmstrom, K. Olsson, and U. Ulmsten Ripening of the human uterine cervix related to changes in collagen, glycosaminoglycans, and collagenolytic activity Am J Obstet Gynecol 147 1983 662 666 (Pubitemid 14242437)
5. T. Rechberger, N. Uldbjerg, and H. Oxlund Connective tissue changes in the cervix during normal pregnancy and pregnancy complicated by cervical incompetence Obstet Gynecol 71 1988 563 567 (Pubitemid 18097641)
6. K. Chwalisz, M. Benson, P. Scholz, J. Daum, H.M. Beier, and C. Hegele-Hartung Cervical ripening with the cytokines interleukin 8, interleukin 1 beta and tumour necrosis factor alpha in guinea-pigs Hum Reprod 9 1994 2173 2181 (Pubitemid 24354470)
7. L.C. Junqueira, M. Zugaib, G.S. Montes, O.M. Toledo, R.M. Krisztan, and K.M. Shigihara Morphologic and histochemical evidence for the occurrence of collagenolysis and for the role of neutrophilic polymorphonuclear leukocytes during cervical dilation Am J Obstet Gynecol 138 1980 273 281 (Pubitemid 10018415)
8. R. Osmers, W. Rath, and B.C. Adelmann-Grill Origin of cervical collagenase during parturition Am J Obstet Gynecol 166 1992 1455 1460
9. C.G. Liggins Cervical ripening as an inflammatory reaction D.A. Elwood, A.B.M. Andersson, Cervix in pregnancy and labour 1981 Churchill Livingstone Edinburgh, Scotland 1 9
10. W. Glassman, M. Byam-Smith, and R.E. Garfield Changes in rat cervical collagen during gestation and after antiprogesterone treatment as measured in vivo with light-induced autofluorescence Am J Obstet Gynecol 173 1995 1550 1556
11. K. Clark, H. Ji, H. Feltovich, J. Janowski, C. Carroll, and E.K. Chien Mifepristone-induced cervical ripening: structural, biomechanical, and molecular events Am J Obstet Gynecol 194 2006 1391 1398
12. K. Chwalisz, and R.E. Garfield Antiprogestins in the induction of labor Ann N Y Acad Sci 734 1994 387 413
13. H. Ji, T.L. Dailey, V. Long, and E.K. Chien Androgen-regulated cervical ripening: a structural, biomechanical, and molecular analysis Am J Obstet Gynecol 198 2008 543.e1 543.e9
14. L. Shi, S.Q. Shi, G.R. Saade, K. Chwalisz, and R.E. Garfield Studies of cervical ripening in pregnant rats: effects of various treatments Mol Hum Reprod 6 2000 382 389 (Pubitemid 30171527)
15. H. Maul, L. Shi, S.G. Marx, R.E. Garfield, and G.R. Saade Local application of platelet-activating factor induces cervical ripening accompanied by infiltration of polymorphonuclear leukocytes in rats Am J Obstet Gynecol 187 2002 829 833 (Pubitemid 35178364)
16. E.H. Bishop Pelvic scoring for elective induction Obstet Gynecol 24 1964 266 268
17. J.M. Crane Factors predicting labor induction success: a critical analysis Clin Obstet Gynecol 49 2006 573 584 (Pubitemid 44181430)
18. C.T. Fittkow, S.Q. Shi, E. Bytautiene, G. Olson, G.R. Saade, and R.E. Garfield Changes in light-induced fluorescence of cervical collagen in guinea pigs during gestation and after sodium nitroprusside treatment J Perinat Med 29 2001 535 543 (Pubitemid 33130999)
19. R.J. Kuon, S.Q. Shi, and H. Maul Pharmacologic actions of progestins to inhibit cervical ripening and prevent delivery depend on their properties, the route of administration, and the vehicle Am J Obstet Gynecol 202 2010 455.e1 455.e9
20. E.B. da Fonseca, R.E. Bittar, M.H. Carvalho, and M. Zugaib Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study Am J Obstet Gynecol 188 2003 419 424 (Pubitemid 36249980)
21. E.A. DeFranco, J.M. O'Brien, and C.D. Adair Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo-controlled trial Ultrasound Obstet Gynecol 30 2007 697 705 (Pubitemid 47612690)
22. J.M. O'Brien, C.D. Adair, and D.F. Lewis Progesterone vaginal gel for the reduction of recurrent preterm birth: primary results from a randomized, double-blind, placebo-controlled trial Ultrasound Obstet Gynecol 30 2007 687 696 (Pubitemid 47612689)
23. E.B. Fonseca, E. Celik, M. Parra, M. Singh, and K.H. Nicolaides Progesterone and the risk of preterm birth among women with a short cervix N Engl J Med 357 2007 462 469 (Pubitemid 47204875)
24. F. Facchinetti, S. Paganelli, G. Comitini, G. Dante, and A. Volpe Cervical length changes during preterm cervical ripening: effects of 17-alpha-hydroxyprogesterone caproate Am J Obstet Gynecol 196 2007 453.e1 453.e4 discussion 421
25. J.M. O'Brien, E.A. Defranco, and C.D. Adair Effect of progesterone on cervical shortening in women at risk for preterm birth: secondary analysis from a multinational, randomized, double-blind, placebo-controlled trial Ultrasound Obstet Gynecol 34 2009 653 659
26. C.P. Durnwald, C.D. Lynch, H. Walker, and J.D. Iams The effect of treatment with 17 alpha-hydroxyprogesterone caproate on changes in cervical length over time Am J Obstet Gynecol 201 2009 410.e1 410.e5
27. J.W. Johnson, K.L. Austin, G.S. Jones, G.H. Davis, and T.M. King Efficacy of 17alpha-hydroxyprogesterone caproate in the prevention of premature labor N Engl J Med 293 1975 675 680
28. M. Incerti, A. Ghidini, A. Locatelli, S.H. Poggi, and J.C. Pezzullo Cervical length ≤25 mm in low-risk women: a case control study of cerclage with rest vs rest alone Am J Obstet Gynecol 197 2007 315.e1 315.e4
29. A.L. Jorgensen, Z. Alfirevic, C. Tudur Smith, and P.R. Williamson Cervical stitch (cerclage) for preventing pregnancy loss: individual patient data meta-analysis BJOG 114 2007 1460 1476 (Pubitemid 350077432)
30. A.C. Vidaeff, and S.M. Ramin From concept to practice: the recent history of preterm delivery prevention: part II, subclinical infection and hormonal effects Am J Perinatol 23 2006 75 84
31. Y.J. Blumenfeld, and D.J. Lyell Prematurity prevention: the role of acute tocolysis Curr Opin Obstet Gynecol 21 2009 136 141
32. K. Higby, E.M. Xenakis, and C.J. Pauerstein Do tocolytic agents stop preterm labor? A critical and comprehensive review of efficacy and safety Am J Obstet Gynecol 168 1993 1247 1259 (Pubitemid 23122176)
33. R.E. Garfield, J.M. Gasc, and E.E. Baulieu Effects of the antiprogesterone RU 486 on preterm birth in the rat Am J Obstet Gynecol 157 1987 1281 1285 (Pubitemid 17163822)
34. W.S. Rasband ImageJ (National Institutes of Health; 1997-2009) http://rsb.info.nih.gov/ij/ Accessed Aug. 2, 2010
35. M.D. Abramoff, P.J. Magelhaes, and S.J. Ram Image processing with ImageJ Biophotonics International 11 2004 36 42
36. H. Maul, L. Mackay, and R.E. Garfield Cervical ripening: biochemical, molecular, and clinical considerations Clin Obstet Gynecol 49 2006 551 563 (Pubitemid 44181428)
37. H. Maul, G. Olson, C.T. Fittkow, G.R. Saade, and R.E. Garfield Cervical light-induced fluorescence in humans decreases throughout gestation and before delivery: preliminary observations Am J Obstet Gynecol 188 2003 537 541 (Pubitemid 36249998)
38. R. Osmers, W. Rath, M.A. Pflanz, W. Kuhn, H.W. Stuhlsatz, and M. Szeverenyi Glycosaminoglycans in cervical connective tissue during pregnancy and parturition Obstet Gynecol 81 1993 88 92 (Pubitemid 23041709)
39. R.G. Osmers, J. Blaser, W. Kuhn, and H. Tschesche Interleukin-8 synthesis and the onset of labor Obstet Gynecol 86 1995 223 229
40. M.L. Akins, K. Luby-Phelps, and M. Mahendroo Second harmonic generation imaging as a potential tool for staging pregnancy and predicting preterm birth J Biomed Opt 15 2010 026020
41. V.N. Breeveld-Dwarkasing, J.M. te Koppele, R.A. Bank, G.C. van der Weijden, M.A. Taverne, and F.M. van Dissel-Emiliani Changes in water content, collagen degradation, collagen content, and concentration in repeated biopsies of the cervix of pregnant cows Biol Reprod 69 2003 1608 1614 (Pubitemid 37362845)
42. A. Csapo Progesterone block Am J Anat 98 1956 273 291
43. J. Murray Natural progesterone: what role in women's health care? Women's Health Primary Care 1 1998 671 687