-
1
-
-
77957910119
-
Dementia revealed: Novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities
-
pii
-
Naj AC, Beecham GW, Martin ER, Gallins PJ, Powell EH, Konidari I, Whitehead PL, Cai G, Haroutunian V, Scott WK, Vance JM, Slifer MA, Gwirtsman HE, Gilbert JR, Haines JL, Buxbaum JD, Pericak-Vance MA (2010) Dementia revealed: Novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. PLoS Genet 6, pii: E1001130.
-
(2010)
PLoS Genet
, vol.6
-
-
Naj, A.C.1
Beecham, G.W.2
Martin, E.R.3
Gallins, P.J.4
Powell, E.H.5
Konidari, I.6
Whitehead, P.L.7
Cai, G.8
Haroutunian, V.9
Scott, W.K.10
Vance, J.M.11
Slifer, M.A.12
Gwirtsman, H.E.13
Gilbert, J.R.14
Haines, J.L.15
Buxbaum, J.D.16
Pericak-Vance, M.A.17
-
2
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TF, McCarroll SA, Visscher PM (2009) Finding the missing heritability of complex diseases. Nature 461, 747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
Cho, J.H.11
Guttmacher, A.E.12
Kong, A.13
Kruglyak, L.14
Mardis, E.15
Rotimi, C.N.16
Slatkin, M.17
Valle, D.18
Whittemore, A.S.19
Boehnke, M.20
Clark, A.G.21
Eichler, E.E.22
Gibson, G.23
Haines, J.L.24
Mackay, T.F.25
McCarroll, S.A.26
Visscher, P.M.27
more..
-
3
-
-
0036301635
-
A second locus for very-late-onset Alzheimer Disease: A genome scan reveals linkage to 20p and epistasis between 20p and the Amyloid Precursor Protein region
-
DOI 10.1086/341034
-
Olson JM, Goddard KA, Dudek DM (2002) A second locus for very-late-onset Alzheimer disease: A genome scan reveals linkage to 20 p and epistasis between 20 p and the amyloid precursor protein region. Am J Hum Genet 71, 154-161. (Pubitemid 34734716)
-
(2002)
American Journal of Human Genetics
, vol.71
, Issue.1
, pp. 154-161
-
-
Olson, J.M.1
Goddard, K.A.B.2
Dudek, D.M.3
-
4
-
-
14844297720
-
Disruption of the Mthfd1 gene reveals a monofunctional 10- formyltetrahydrofolate synthetase in mammalian mitochondria
-
DOI 10.1074/jbc.M409380200
-
Christensen KE, Patel H, Kuzmanov U, Mejia NR, MacKenzie RE (2005) Disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria. J Biol Chem 280, 7597-7602. (Pubitemid 40349652)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.9
, pp. 7597-7602
-
-
Christensen, K.E.1
Patel, H.2
Kuzmanov, U.3
Mejia, N.R.4
MacKenzie, R.E.5
-
5
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
DOI 10.1056/NEJMoa011613
-
Seshadri S, Beiser A, Selhub J, Jacques PF, Rosenberg IH, D'Agostino RB, Wilson PW, Wolf PA (2002) Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 346, 476-483. (Pubitemid 34441738)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.7
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
Jacques, P.F.4
Rosenberg, I.H.5
D'Agostino, R.B.6
Wilson, P.W.F.7
Wolf, P.A.8
-
6
-
-
0031597388
-
12, and serum total homocysteine levels in confirmed Alzheimer disease
-
Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM(1998) Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 55, 1449-1455. (Pubitemid 28525506)
-
(1998)
Archives of Neurology
, vol.55
, Issue.11
, pp. 1449-1455
-
-
Clarke, R.1
Smith, A.D.2
Jobst, K.A.3
Refsum, H.4
Sutton, L.5
Ueland, P.M.6
-
7
-
-
0031902352
-
Total serum homocysteine in senile dementia of Alzheimer type
-
DOI 10.100 2/(SICI)1099-1 166(199 804)13:4<2 35::AID-GPS 761>3.0.CO;2-8
-
McCaddon A, Davies G, Hudson P, Tandy S, Cattell H (1998) Total serum homocysteine in senile dementia of Alzheimer type. Int J Geriatr Psychiatry 13, 235-239. (Pubitemid 28194997)
-
(1998)
International Journal of Geriatric Psychiatry
, vol.13
, Issue.4
, pp. 235-239
-
-
McCaddon, A.1
Davies, G.2
Hudson, P.3
Tandy, S.4
Cattell, H.5
-
8
-
-
77954510763
-
CALHM1P86L polymorphism is associated with late-onset Alzheimer's disease in a recessive model
-
Boada M, Antunez C, Lopez-Arrieta J, Galan JJ, Moron FJ, Hernandez I, Marin J, Martinez-Lage P, Alegret M, Carrasco JM, Moreno C, Real LM, Gonzalez-Perez A, Tarraga L, Ruiz A (2010) CALHM1P86L polymorphism is associated with late-onset Alzheimer's disease in a recessive model. J Alzheimers Dis 20, 247-251.
-
(2010)
J Alzheimers Dis
, vol.20
, pp. 247-251
-
-
Boada, M.1
Antunez, C.2
Lopez-Arrieta, J.3
Galan, J.J.4
Moron, F.J.5
Hernandez, I.6
Marin, J.7
Martinez-Lage, P.8
Alegret, M.9
Carrasco, J.M.10
Moreno, C.11
Real, L.M.12
Gonzalez-Perez, A.13
Tarraga, L.14
Ruiz, A.15
-
9
-
-
77952307991
-
Genome-wide analysis of genetic loci associated with Alzheimer disease
-
Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, LongstrethWTJr, JanssensAC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM (2010) Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 303, 1832-1840.
-
(2010)
JAMA
, vol.303
, pp. 1832-1840
-
-
Seshadri, S.1
Fitzpatrick, A.L.2
Ikram, M.A.3
DeStefano, A.L.4
Gudnason, V.5
Boada, M.6
Bis, J.C.7
Smith, A.V.8
Carassquillo, M.M.9
Lambert, J.C.10
Harold, D.11
Schrijvers, E.M.12
Ramirez-Lorca, R.13
Debette, S.14
Longstreth Jr., W.T.15
Janssens, A.C.16
Pankratz, V.S.17
Dartigues, J.F.18
Hollingworth, P.19
Aspelund, T.20
Hernandez, I.21
Beiser, A.22
Kuller, L.H.23
Koudstaal, P.J.24
Dickson, D.W.25
Tzourio, C.26
Abraham, R.27
Antunez, C.28
Du, Y.29
Rotter, J.I.30
Aulchenko, Y.S.31
Harris, T.B.32
Petersen, R.C.33
Berr, C.34
Owen, M.J.35
Lopez-Arrieta, J.36
Varadarajan, B.N.37
Becker, J.T.38
Rivadeneira, F.39
Nalls, M.A.40
Graff-Radford, N.R.41
Campion, D.42
Auerbach, S.43
Rice, K.44
Hofman, A.45
Jonsson, P.V.46
Schmidt, H.47
Lathrop, M.48
Mosley, T.H.49
Au, R.50
Psaty, B.M.51
Uitterlinden, A.G.52
Farrer, L.A.53
Lumley, T.54
Ruiz, A.55
Williams, J.56
Amouyel, P.57
Younkin, S.G.58
Wolf, P.A.59
Launer, L.J.60
Lopez, O.L.61
Van Duijn, C.M.62
Breteler, M.M.63
more..
-
10
-
-
63249096555
-
GAB2 gene does not modify the risk of Alzheimer's disease in Spanish APOE 4 carriers
-
Ramirez-Lorca R, Boada M, Saez ME, Hernandez I, Mauleon A, Rosende-Roca M, Martinez-Lage P, Gutierrez M, RealLM, Lopez-Arrieta J, Gayan J, Antunez C, Gonzalez-Perez A, Tarraga L, Ruiz A (2009) GAB2 gene does not modify the risk of Alzheimer's disease in Spanish APOE 4 carriers. J Nutr Health Aging 13, 214-219.
-
(2009)
J Nutr Health Aging
, vol.13
, pp. 214-219
-
-
Ramirez-Lorca, R.1
Boada, M.2
Saez, M.E.3
Hernandez, I.4
Mauleon, A.5
Rosende-Roca, M.6
Martinez-Lage, P.7
Gutierrez, M.8
Real, L.M.9
Lopez-Arrieta, J.10
Gayan, J.11
Antunez, C.12
Gonzalez-Perez, A.13
Tarraga, L.14
Ruiz, A.15
-
11
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K,Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schurmann B, van den Bussche H, Heuser I, Kornhuber J,Wiltfang J, Dichgans M, Frolich L, Hampel H, Hull M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van BroeckhovenC,Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Muhleisen TW, Nothen MM, Moebus S, Jockel KH, Klopp N,Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41, 1088-1093.
-
(2009)
Nat Genet
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
Hamshere, M.L.6
Pahwa, J.S.7
Moskvina, V.8
Dowzell, K.9
Williams, A.10
Jones, N.11
Thomas, C.12
Stretton, A.13
Morgan, A.R.14
Lovestone, S.15
Powell, J.16
Proitsi, P.17
Lupton, M.K.18
Brayne, C.19
Rubinsztein, D.C.20
Gill, M.21
Lawlor, B.22
Lynch, A.23
Morgan, K.24
Brown, K.S.25
Passmore, P.A.26
Craig, D.27
McGuinness, B.28
Todd, S.29
Holmes, C.30
Mann, D.31
Smith, A.D.32
Love, S.33
Kehoe, P.G.34
Hardy, J.35
Mead, S.36
Fox, N.37
Rossor, M.38
Collinge, J.39
Maier, W.40
Jessen, F.41
Schurmann, B.42
Van Den Bussche, H.43
Heuser, I.44
Kornhuber, J.45
Wiltfang, J.46
Dichgans, M.47
Frolich, L.48
Hampel, H.49
Hull, M.50
Rujescu, D.51
Goate, A.M.52
Kauwe, J.S.53
Cruchaga, C.54
Nowotny, P.55
Morris, J.C.56
Mayo, K.57
Sleegers, K.58
Bettens, K.59
Engelborghs, S.60
De Deyn, P.P.61
Van Broeckhoven, C.62
Livingston, G.63
Bass, N.J.64
Gurling, H.65
McQuillin, A.66
Gwilliam, R.67
Deloukas, P.68
Al-Chalabi, A.69
Shaw, C.E.70
Tsolaki, M.71
Singleton, A.B.72
Guerreiro, R.73
Muhleisen, T.W.74
Nothen, M.M.75
Moebus, S.76
Jockel, K.H.77
Klopp, N.78
Wichmann, H.E.79
Carrasquillo, M.M.80
Pankratz, V.S.81
Younkin, S.G.82
Holmans, P.A.83
O'Donovan, M.84
Owen, M.J.85
Williams, J.86
more..
-
12
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fievet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O, de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossu P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanche H, Dartigues JF, Tzourio C, Gut I,Van BroeckhovenC, Alperovitch A, Lathrop M, Amouyel P (2009) Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41, 1094-1099.
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
Hiltunen, M.6
Combarros, O.7
Zelenika, D.8
Bullido, M.J.9
Tavernier, B.10
Letenneur, L.11
Bettens, K.12
Berr, C.13
Pasquier, F.14
Fievet, N.15
Barberger-Gateau, P.16
Engelborghs, S.17
De Deyn, P.18
Mateo, I.19
Franck, A.20
Helisalmi, S.21
Porcellini, E.22
Hanon, O.23
De Pancorbo, M.M.24
Lendon, C.25
Dufouil, C.26
Jaillard, C.27
Leveillard, T.28
Alvarez, V.29
Bosco, P.30
Mancuso, M.31
Panza, F.32
Nacmias, B.33
Bossu, P.34
Piccardi, P.35
Annoni, G.36
Seripa, D.37
Galimberti, D.38
Hannequin, D.39
Licastro, F.40
Soininen, H.41
Ritchie, K.42
Blanche, H.43
Dartigues, J.F.44
Tzourio, C.45
Gut, I.46
Van Broeckhoven, C.47
Alperovitch, A.48
Lathrop, M.49
Amouyel, P.50
more..
|