Coupling vascular and myocardial inflammatory injury into a common phenotype of cardiovascular dysfunction: Systemic inflammation and aging - A mini-review

Gerontology

Volumn 57, Issue 4, 2011, Pages 295-303

  Puntmann, Valentina O ^a   Taylor, Peter C ^a   Mayr, Manuel ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiovascular disease; Imaging; Immunomics; Inflammation; integrated; myocardial; noninvasive; Proteomics

Indexed keywords

ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; AGING; ATHEROSCLEROSIS; CARDIAC IMAGING; CARDIOVASCULAR INFLAMMATION; CARDIOVASCULAR RISK; DIABETES MELLITUS; ENDOTHELIAL DYSFUNCTION; EXTRACELLULAR MATRIX; HEART MUSCLE INJURY; HEART VENTRICLE REMODELING; HUMAN; HYPERTENSION; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEOMICS; REVIEW; RHEUMATOID ARTHRITIS; RISK FACTOR;

AGED; AGING; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASES; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL REPERFUSION INJURY; PHENOTYPE; PROGNOSIS; PROTEOMICS; RISK ASSESSMENT; VENTRICULAR REMODELING;

EID: 79959671348     PISSN: 0304324X     EISSN: 14230003     Source Type: Journal    
DOI: 10.1159/000316577     Document Type: Review

References (40)

1. Libby P, Ridker PM, Hansson GK: Inflammation in atherosclerosis from pathophysiology to practice. J Am Coll Cardiol 2009; 54: 2129-2138.
2. Lüscher TF, Steffel J, Eberli FR, Joner M, Na-kazawa G, Tanner FC, Virmani R: Drug-eluting stent and coronary thrombosis: biological mechanisms and clinical implications. Circulation 2007; 115: 1051-1058. (Pubitemid 46328299)
3. Cai H, Harrison DG: Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 2000; 87:840-844.
4. Püntmann VO, Hussain MB, Mayr M, Xu Q, Singer DR: Role of oxidative stress in angio-tensin-II mediated contraction of human conduit arteries in patients with cardiovascular disease. Vascul Pharmacol 2005; 43: 277-282. (Pubitemid 41586215)
5. Hussain MB, Puntmann VO, Mayr M, Khong T, Singer DRJ: The role of oxidant stress in angiotensin II-mediated contraction of human resistance arteries in the state of health and the presence of cardiovascular disease. Vascul Pharmacol 2006; 45: 395-399. (Pubitemid 44765301)
6. Mitchell GF: Arterial stiffness and wave reflection: biomarkers of cardiovascular risk. Artery Res 2009; 3: 56-64.
7. Mattace-Raso FUS, van der Cammen TJM, van der Meer IM, Schalekamp MADH, Asmar R, Hofman A, Witteman JCM: Creactive protein and arterial stiffness in older adults: the Rotterdam Study. Atherosclerosis 2004; 176:111-116. (Pubitemid 39078652)
8. Van Leuven SI, Franssen R, Kastelein JJ, Levi M, Stroes ES, Tak PP: Systemic inflammation as a risk factor for atherothrombosis. Rheumatology 2008; 47:3-7. (Pubitemid 350286254)
9. Gonzalez-Gay MA, Gonzalez-Juanatey C, Pineiro A, Garcia-Porrua C, Testa A, Llorca J: High-grade C-reactive protein elevation correlates with accelerated atherogenesis in patients with rheumatoid arthritis. J Rheu-matol 2005; 32:1219-1223. (Pubitemid 40995373)
10. Taylor PC, Sivakumar B: Hypoxia and angio-genesis in rheumatoid arthritis. Curr Opin Rheumatol 2005; 17:293-298.
11. Wick G, Knoflach M, Xu Q: Autoimmune and inflammatory mechanisms in atherosclerosis. Annu Rev Immunol 2004; 22:361-403. (Pubitemid 38680427)
12. Xu Q, Willeit J, Marosi M, Kleindienst R, Oberhollenzer F, Kiechl S, Stulnig T, Luef G, Wick G: Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis. La ncet 1993; 341: 255-325.
13. Mayr M, Kiechl S, Willeit J, Wick G, Xu Q: Infections, immunity, and atherosclerosis: associations of antibodies to Chlamydia pneumoniae, Helicobacter pylori, and cyto-megalovirus with immune reactions to heat-shock protein 60 and carotid or femoral atherosclerosis. Circulation 2000; 102: 833-839.
14. Liuzzo G, Kopecky SL, Frye RL, O'Fallon WM, Maseri A, Goronzy JJ, Weyand CM: Perturbation of the T-cell repertoire in patients with unstable angina. Circulation 1999; 100:2135-2139.
15. Metzler B, Mayr M, Dietrich H, Singh M, Wiebe E, Xu Q, Wick G: Inhibition of arteriosclerosis by T-cell depletion in normocho-lesterolemic rabbits immunized with heat shock protein 65. Arterioscler Thromb Vasc Biol 1999; 19: 1905-1911. (Pubitemid 29379920)
16. Mann DL: Inflammatory mediators and the failing heart: past, present and foreseeable future. Circ Res 2002; 91:988-998. (Pubitemid 35416635)
17. Hamid T, Gu Y, Ortines RV, Bhattacharya C, Wang G, Xuan YT, Prabhu SD: Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: role of nuclear factor-kappaB and inflammatory activation. Circulation 2009; 119: 1386-1397.
18. Pauschinger M, Chandrasekharan K, Schultheiss HP: Myocardial remodeling in viral heart disease: possible interactions between inflammatory mediators and MMP-TIMP system. Heart Fail Rev 2004; 9: 21-31. (Pubitemid 38196074)
19. Currie RW, Tanguay RM, Kingma JG Jr: Heat-shock response and limitation of tissue necrosis during occlusion/reperfusion in rabbit hearts. Circulation 1993; 87: 963-971. (Pubitemid 23070828)
20. Piot C, Croisille P, Staat P, Thibault H, Riou-fol G, Mewton N, Elbelghiti R, Cung TT, Bonnefoy E, Angoulva nt D, Macia C, Raczka F, Sportouch C, Gahide G, Finet G, André-Fouët X, Revel D, Kirkorian G, Monassier JP, Derumeaux G, Ovize M: Effect of cyclospo-rine on reperfusion injury in acute myocar-dial infarction. N Engl J Med 2008; 359:473-481.
21. Bernhard D, Laufer G: The aging cardiomyo-cyte: a mini-review. Gerontology 2008; 54: 24-31.
22. Li SY, Du M, Dolence EK, Fang CX, Mayer GE, Ceylan-Isik AF, LaCour KH, Yang X, Wilbert CJ, Sreejayan N, Ren J: Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification. Aging Cell 2005; 4: 57-64. (Pubitemid 41632904)
23. Barakat K, Wilkinson P, Deaner A, Fluck D, Ranjadayalan K, Timmis A: How should age affect management of acute myocardial infarction? A prospective cohort study. Lancet 1999; 353: 955-959. (Pubitemid 29132603)
24. Puntmann VO: How-to guide on biomarkers: biomarker definitions, validation and applications with examples from cardiovascular disease. Postgrad Med J 2009; 85: 538-545.
25. Mayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, John R: Griffiths JR, Xu Q, Tedgui A and Boulanger CM: Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Circ Cardiovasc Genet 2009; 2: 379-388.
26. Puntmann VO, Taylor PC, Barr A, Schna-ckenburg B, Jahnke C, Paetsch I: Towards understanding the phenotypes of myocar-dial involvement in the presence of self-limiting and sustained systemic inflammation: a magnetic resonance imaging study. Rheu-matolog y 2010; 49: 528-535.
27. Mosedale DE, Chauhan A, Schofield PM, Grainger DJ: A pattern of anti-carbohydrate antibody responses present in patients with advanced atherosclerosis. J Immunol Methods 2006; 309: 182-191. (Pubitemid 43190814)
28. Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M: Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood 2009; 114:723-732.
29. Xu QB, Oberhuber G, Gruschwitz M, Wick G: Immunology of atherosclerosis: cellular composition and major histocompatibility complex class II antigen expression in aortic intima, fatty streaks, and atherosclerotic plaques in young and aged human specimens. Clin Immunol Immunopathol 1990; 56: 344-359. (Pubitemid 20269296)
30. Pham T, Gregg CJ, Karp F, Chow R, Padler-Karavani V, Cao H, Chen X, Witztum JL, Varki NM, Varki A: Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium. Blood 2009; 114:5225-5235.
31. Padler-Karavani V, Yu H, Cao H, Chokha-wala H, Karp F, Varki N, Chen X, Varki A: Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: potential implications for disease. Glycobiology 2008; 18: 818-830.
32. Binder CJ, Hörkkö S, Dewan A, Chang MK, Kieu EP, Goodyear CS, Shaw PX, Palinski W, Witztum JL, Silverman GJ: Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med 2003; 9: 736-743. (Pubitemid 36749223)
33. Mayr M, Kiechl S, Tsimikas S, Miller E, Sheldon J, Willeit J, Witztum JL, Xu Q: Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study. J Am Coll Cardiol 2006; 47:2436-2443. (Pubitemid 43866376)
34. Xu Q, Dietrich H, Steiner HJ, Gown AM, Schoel B, Mikuz G, Kaufmann SH, Wick G: Induction of arteriosclerosis in normocho-lesterolemic rabbits by immunization with heat shock protein 65. Arterioscler Thromb 1992; 12:789-799.
35. Maron R, Sukhova G, Faria AM, Hoffmann E, Mach F, Libby P, Weiner HL: Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice. Circulation 2002; 106: 1708-1715.
36. Tonetti MS, D'Aiuto F, Nibali L, Donald A, Storry C, Parkar M, Suvan J, Hingorani AD, Vallance P, Deanfield J: Treatment of peri-odontitis and endothelial function. N Engl J Med 2007; 356: 911-920.
37. Klein C, Nagel E, Gebker R, Kelle S, Schna-ckenburg B, Graf K, Dreysse S, Fleck E: Magnetic resonance adenosine perfusion imaging in patients after coronary artery bypass graft surgery. JACC Cardiovasc Imaging 2009; 2:437-445.
38. Von Birgelen C, Hartmann M, Mintz GS, van Houwelingen KG, Deppermann N, Schmermund A, Bose D, Eggebrecht H, Neumann T, Gossl M, Wieneke H, Erbel R: Relationship between cardiovascular risk as predicted by established risk scores versus plaque progression as measured by serial in-travascular ultrasound in left main coronary arteries. Circulation 2004; 110: 1579-1585. (Pubitemid 39297979)
39. Rieber J, Meissner O, Babaryka G, Reim S, Oswald M, Koenig A, Schiele TM, Shapiro M, Theisen K, Reiser MF, Klauss V, Hoffmann U: Diagnostic accuracy of optical coherence tomography and intravascular ultrasound for the detection and characterization of atherosclerotic plaque composition in ex-vivo coronary specimens: a comparison with histology. Coron Artery Dis 2006; 17:425-430. (Pubitemid 44309782)
40. Wick MC, Kremser C, Frischauf S, Wick G: In vivo molecular imaging of vascular stress. Cel l Stress Chaperones 2008; 13: 263-273.