Increased lymphangiogenesis and hemangiogenesis in infant cornea

Lymphatic Research and Biology

Volumn 9, Issue 2, 2011, Pages 109-114

  Yuen, Don ^a   Leu, Rose ^a   Sadovnikova, Anna ^a   Chen, Lu ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL; CELL INFILTRATION; CONTROLLED STUDY; CORNEA HEMANGIOGENESIS; CORNEA LYMPHANGIOGENESIS; DIGITAL IMAGING; EYE DEVELOPMENT; IMMUNOFLUORESCENCE MICROSCOPY; IN VIVO STUDY; INFLAMMATION; LYMPH VESSEL; LYMPHANGIOGENESIS; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SLIT LAMP;

ANIMALS; CORNEA; HUMANS; INFANT; LYMPHANGIOGENESIS; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; RETINAL VESSELS;

EID: 79959598371     PISSN: 15396851     EISSN: 15578585     Source Type: Journal    
DOI: 10.1089/lrb.2011.0005     Document Type: Article

References (29)

1. Tammela T, Alitalo K. Lymphangiogenesis: Molecular mechanisms and future promise. Cell. 2010;140:460-476.
2. Rockson SG. Lymphatic research: Past, present, and future. Lymphat Res Biol. 2009;7:183-187.
3. Chen L. Ocular lymphatics: State-of-the-art review. Lymphology. 2009;42:66-76.
4. Brown P. Lymphatic system: Unlocking the drains. Nature. 2005;436:456-458. (Pubitemid 41112892)
5. Folkman J, Kaipainen A. Genes tell lymphatics to sprout or not. Nat Immunol. 2004;5:11-12. (Pubitemid 38081460)
6. Oliver G, Detmar M. The rediscovery of the lymphatic system: Old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev. 2002;16:773-783. (Pubitemid 34280101)
7. Banerji S, Ni J, Wang SX, Clasper S, Su J, Tammi R, Jones M, Jackson DG. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol. 1999;144:789-801. (Pubitemid 29234556)
8. Rockson SG. The broad spectrum of lymphatic health and disease. Lymphat Res Biol. 2010;8:101.
9. Muthukkaruppan V, Auerbach R. Angiogenesis in the mouse cornea. Science. 1979;205:1416-1418. (Pubitemid 10226660)
10. Gimbrone MA, Jr., Cotran RS, Leapman SB, Folkman J. Tumor growth and neovascularization: An experimental model using the rabbit cornea. J Natl Cancer Inst. 1974;52: 413-427.
11. Chen L, Hann B, Wu L. Experimental models to study lymphatic and blood vascular metastasis. J Surg Oncol. 2011;103:475-483.
12. Cursiefen C, Chen L, Dana MR, Streilein JW. Corneal lymphangiogenesis: Evidence, mechanisms, and implications for corneal transplant immunology. Cornea. 2003;22:273-281. (Pubitemid 36359171)
13. Chong EM, Dana MR. Graft failure IV. Immunologic mechanisms of corneal transplant rejection. Int Ophthalmol. 2008;28:209-222.
14. Chen L, Huq S, Gardner H, de Fougerolles AR, Barabino S, Dana MR. Very late antigen 1 blockade markedly promotes survival of corneal allografts. Arch. Ophthal. 2007;125:783-788. (Pubitemid 46919739)
15. Dietrich T, Bock F, Yuen D, Hos D, Bachmann BO, Zahn G, Wiegand S, Chen L, Cursiefen C. Cutting edge: Lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation. J Immunol. 2010;184:535-539.
16. Vanathi M, Panda A, Vengayil S, Chaudhuri Z, Dada T: Pediatric keratoplasty. Surv Ophthalmol. 2009;54:245-271.
17. Al-Ghamdi A, Al-Rajhi A, Wagoner MD: Primary pediatric keratoplasty: Indications, graft survival, and visual outcome. J AAPOS. 2007;11:41-47. (Pubitemid 46329468)
18. Dana MR, Moyes AL, Gomes JA, Rosheim KM, Schaumberg DA, Laibson PR, Holland EJ, Sugar A, Sugar J: The indications for and outcome in pediatric keratoplasty. A multicenter study. Ophthalmology. 1995;102:1129-1138.
19. Schwartzkopff J, Berger M, Birnbaum F, Bohringer D, Reinhard T: Accelerated corneal graft rejection in baby rats. Br J Ophthalmol. 2010;94:1062-1066.
20. Chen L, Hamrah P, Cursiefen C, Zhang Q, Pytowski B, Streilein JW, Dana MR: Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity. Nat Med. 2004;10:813-815. (Pubitemid 39070853)
21. Zhang H, Hu X, Tse J, Tilahun F, Qiu M, Chen L: Spontaneous lymphatic vessel formation and regression in the murine cornea. Invest Ophthalmol Vis Sci. 2011;52:334-338.
22. Grimaldo S, Yuen D, Ecoiffier T, Chen L: Very late antigen-1 mediates corneal lymphangiogenesis. Invest Ophthalmol Vis Sci. 2011 Mar 2 [Epub ahead of print].
23. Yuen D, Pytowski B, Chen L: Combined blockade of VEGFR- 2 and VEGFR-3 inhibits inflammatory lymphangiogenesis in early and middle stages. Invest Ophthalmol Vis Sci. 2011;52: 2593-2597.
24. Ecoiffier T, Yuen D, Chen L. Differential distribution of blood and lymphatic vessels in the murine cornea. Invest Ophthalmol Vis Sci 2010;51:2436-2440.
25. Dastjerdi MH, Al-Arfaj KM, Nallasamy N, Hamrah P, Jurkunas UV, Pineda R, Pavan-Langston D, Dana R: Topical bevacizumab in the treatment of corneal neovascularization: Results of a prospective, open-label, noncomparative study. Arch Ophthalmol. 2009;127:381-389.
26. Chung ES, Chauhan SK, Jin Y, Nakao S, Hafezi-Moghadam A, van Rooijen N, Zhang Q, Chen L, Dana R: Contribution of macrophages to angiogenesis induced by vascular endothelial growth factor receptor-3-specific ligands. Am J Pathol. 2009;175:1984-1992.
27. Rashid S, Jin Y, Ecoiffier T, Barabino S, Schaumberg DA, Dana MR: Topical omega-3 and omega-6 fatty acids for treatment of dry eye. Arch Ophthalmol. 2008;126:219-225. (Pubitemid 351240851)
28. Dana MR, Streilein JW: Loss and restoration of immune privilege in eyes with corneal neovascularization. Invest Ophthalmol Vis Sci. 1996;37:2485-2494. (Pubitemid 26391286)
29. Cursiefen C, Chen L, Borges LP, Jackson D, Cao J, Radziejewski C, D'Amore PA, Dana MR, Wiegand SJ, Streilein JW: VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest. 2004;113:1040-1050. (Pubitemid 38544126)