Optimal central nervous system prophylaxis in Philadelphia chromosome-positive acute lymphoblastic leukemia: Collateral damage in the imatinib era?

Leukemia and Lymphoma

Volumn 52, Issue 7, 2011, Pages 1164-1165

  Bassan, Renato ^a  

^a OSPEDALI RIUNITI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; DASATINIB; IMATINIB; METHOTREXATE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTICOAGULATION; CENTRAL NERVOUS SYSTEM; HUMAN; LUMBAR PUNCTURE; NEUROPROTECTION; NOTE; PHILADELPHIA CHROMOSOME POSITIVE CELL; PRIORITY JOURNAL; PROPHYLAXIS; SUBDURAL HEMATOMA; THROMBOCYTOPENIA;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; FEMALE; HEMATOMA, SUBDURAL; HUMANS; MALE; PIPERAZINES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PYRIMIDINES;

EID: 79959591108     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.575494     Document Type: Note

References (8)

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2. Fielding AK, Buck G, Lazarus HM, et al. Imatinib significantly enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukaemia; final results of the UKALLXII/ ECOG2993 trial. Blood 2010;116(Suppl. 1): Abstract 169.
3. Pfeifer H, Goekbuget N, Volp C, et al. Long-term outcome of 335 adult patients receiving different schedules of imatinib and chemotherapy as front-line treatment for Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL). Blood 2010;116 (Suppl. 1): Abstract 173.
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7. Gokbuget N, Hartog CM, Bassan R, et al. Liposomal cytarabine is effective and tolerable in the treatment of central nervous system relapse of acute lymphoblastic leukemia and very aggressive lymphoma. Haematologica 2011;96:238-244.
8. Porkka K, Koskenvesa P, Lundan T, et al. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia. Blood 2008;112:1005-1012.