Intercellular communication by exchange of cytoplasmic material via tunneling nano-tube like structures in primary human renal epithelial cells

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Domhan, Sophie ^a,b,c   Ma, Lili ^a   Tai, Albert ^a   Anaya, Zachary ^a   Beheshti, Afshin ^a   Zeier, Martin ^c   Hlatky, Lynn ^a   Abdollahi, Amir ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DYE; LATRUNCULIN B; NANOCRYSTAL; NANOTUBE; QUANTUM DOT;

ARTICLE; CELL COMMUNICATION; CELL FRACTIONATION; CELL LABELING; CELL ORGANELLE; CELL STRESS; CELL TRANSPORT; CELL VACUOLE; COCULTURE; CONTROLLED STUDY; CYTOPLASM; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; KIDNEY FUNCTION; KIDNEY PROXIMAL TUBULE; MITOCHONDRION; CELL CULTURE; CYTOLOGY; EPITHELIUM CELL; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; KIDNEY; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOPLASM; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; KIDNEY; MICROSCOPY, FLUORESCENCE;

EID: 79959583875     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021283     Document Type: Article

References (18)

1. Rustom A, Saffrich R, Markovic I, Walther P, Gerdes HH, (2004) Nanotubular highways for intercellular organelle transport. Science 303: 1007-1010 10.1126/science.1093133 [doi];303/5660/1007 [pii].
2. Gerdes HH, Carvalho RN, (2008) Intercellular transfer mediated by tunneling nanotubes. Curr Opin Cell Biol 20: 470-475 S0955-0674(08)00038-0 [pii];10.1016/j.ceb.2008.03.005 [doi].
3. Gerdes HH, Bukoreshtliev NV, Barroso JF, (2007) Tunneling nanotubes: a new route for the exchange of components between animal cells. FEBS Lett 581: 2194-2201 S0014-5793(07)00348-1 [pii];10.1016/j.febslet.2007.03.071 [doi].
4. Koyanagi M, Brandes RP, Haendeler J, Zeiher AM, Dimmeler S, (2005) Cell-to-cell connection of endothelial progenitor cells with cardiac myocytes by nanotubes: a novel mechanism for cell fate changes? Circ Res 96: 1039-1041 01.RES.0000168650.23479.0c [pii];10.1161/01.RES.0000168650.23479.0c [doi].
5. Gurke S, Barroso JF, Hodneland E, Bukoreshtliev NV, Schlicker O, et al. (2008) Tunneling nanotube (TNT)-like structures facilitate a constitutive, actomyosin-dependent exchange of endocytic organelles between normal rat kidney cells. Exp Cell Res 314: 3669-3683 S0014-4827(08)00340-6 [pii];10.1016/j.yexcr.2008.08.022 [doi].
6. Eugenin EA, Gaskill PJ, Berman JW, (2009) Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: a potential mechanism for intercellular HIV trafficking. Cell Immunol 254: 142-148 S0008-8749(08)00157-3 [pii];10.1016/j.cellimm.2008.08.005 [doi].
7. Gerdes HH, (2009) Prions tunnel between cells. Nat Cell Biol 11: 235-236 ncb0309-235 [pii];10.1038/ncb0309-235 [doi].
8. Chinnery HR, Pearlman E, McMenamin PG, (2008) Cutting edge: Membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea. J Immunol 180: 5779-5783 180/9/5779 [pii].
9. Onfelt B, Nedvetzki S, Yanagi K, Davis DM, (2004) Cutting edge: Membrane nanotubes connect immune cells. J Immunol 173: 1511-1513 173/3/1511 [pii].
10. Zhu D, Tan KS, Zhang X, Sun AY, Sun GY, et al. (2005) Hydrogen peroxide alters membrane and cytoskeleton properties and increases intercellular connections in astrocytes. J Cell Sci 118: 3695-3703 jcs.02507 [pii];10.1242/jcs.02507 [doi].
11. Martinez AD, Eugenin EA, Branes MC, Bennett MV, Saez JC, (2002) Identification of second messengers that induce expression of functional gap junctions in microglia cultured from newborn rats. Brain Res 943: 191-201 S0006899302026215 [pii].
12. Eugenin EA, Branes MC, Berman JW, Saez JC, (2003) TNF-alpha plus IFN-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses. J Immunol 170: 1320-1328.
13. Eugenin EA, Eckardt D, Theis M, Willecke K, Bennett MV, et al. (2001) Microglia at brain stab wounds express connexin 43 and in vitro form functional gap junctions after treatment with interferon-gamma and tumor necrosis factor-alpha. Proc Natl Acad Sci U S A 98: 4190-4195 10.1073/pnas.051634298 [doi];051634298 [pii].
14. Gousset K, Schiff E, Langevin C, Marijanovic Z, Caputo A, et al. (2009) Prions hijack tunnelling nanotubes for intercellular spread. Nat Cell Biol 11: 328-336 ncb1841 [pii];10.1038/ncb1841 [doi].
15. Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, et al. (2005) Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest 115: 1743-1755 10.1172/JCI22593 [doi].
16. Bruno S, Grange C, Deregibus MC, Calogero RA, Saviozzi S, et al. (2009) Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol 20: 1053-1067 ASN.2008070798 [pii];10.1681/ASN.2008070798 [doi].
17. Abdollahi A, Hahnfeldt P, Maercker C, Grone HJ, Debus J, et al. (2004) Endostatin's antiangiogenic signaling network. Mol Cell 13: 649-663 S1097276504001029 [pii].
18. Zuba-Surma EK, Kucia M, Abdel-Latif A, Lillard JW Jr, Ratajczak MZ, (2007) The ImageStream System: a key step to a new era in imaging. Folia Histochem Cytobiol 45: 279-290 39/4/2007 [pii].