-
1
-
-
34547784051
-
Mechanisms of tumor-related brain edema
-
Stummer W (2007) Mechanisms of tumor-related brain edema. Neurosurg Focus 22:E8
-
(2007)
Neurosurg Focus
, vol.22
-
-
Stummer, W.1
-
2
-
-
33646428102
-
Blood-brain barrier interfaces and brain tumors
-
Lee SW, Kim WJ, Park JA, Choi YK, Kwon YW, Kim KW (2006) Blood-brain barrier interfaces and brain tumors. Arch Pharm Res 29:265-275 (Pubitemid 43685278)
-
(2006)
Archives of Pharmacal Research
, vol.29
, Issue.4
, pp. 265-275
-
-
Lee, S.-W.1
Woo, J.K.2
Park, J.A.3
Yoon, K.C.4
Kwon, Y.-W.5
Kim, K.-W.6
-
3
-
-
0029939878
-
Corticotropin-releasing factor decreases vasogenic brain edema
-
Tjuvajev J, Uehara H, Desai R, Beattie B, Matei I, Zhou Y, Kreek MJ, Koutcher J, Blasberg R (1996) Corticotropin-releasing factor decreases vasogenic edema. Cancer Res 56:1352-1360 (Pubitemid 26080979)
-
(1996)
Cancer Research
, vol.56
, Issue.6
, pp. 1352-1360
-
-
Tjuvajev, J.1
Uehara, H.2
Desai, R.3
Beattie, B.4
Matei, C.5
Zhou, Y.6
Kreek, M.-J.7
Koutcher, J.8
Blasberg, R.9
-
4
-
-
8344241192
-
The management of brain edema in brain tumors
-
DOI 10.1097/01.cco.0000142076.52721.b3
-
Kaal EC, Vecht CJ (2004) The management of brain edema in brain tumors. Curr Opin Oncol 16:593-600 (Pubitemid 39482980)
-
(2004)
Current Opinion in Oncology
, vol.16
, Issue.6
, pp. 593-600
-
-
Kaal, E.C.A.1
Vecht, C.J.2
-
5
-
-
0038407615
-
Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists
-
DOI 10.1016/S1043-2760(02)00670-7, PII S1043276002006707
-
Grammatopoulos DK, Chrousos GP (2002) Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists. Trends Endocrinol Metab 13:436-444 (Pubitemid 36733938)
-
(2002)
Trends in Endocrinology and Metabolism
, vol.13
, Issue.10
, pp. 436-444
-
-
Grammatopoulos, D.K.1
Chrousos, G.P.2
-
6
-
-
33646521497
-
The molecular mechanisms underlying the regulation of the biological activity of corticotropin releasing hormone receptors: Implications for physiology and pathophysiology
-
Hillhouse EW, Grammatopoulos OK (2006) The molecular mechanisms underlying the regulation of the biological activity of corticotropin releasing hormone receptors: implications for physiology and pathophysiology. Endocr Rev 27:260-286
-
(2006)
Endocr Rev
, vol.27
, pp. 260-286
-
-
Hillhouse, E.W.1
Grammatopoulos, O.K.2
-
7
-
-
0037622756
-
Expression of CRF1 and CRF2 receptors in human cancers
-
DOI 10.1210/jc.2002-021853
-
Reubi JC, Waser W, Vale W, Rivier J (2003) Expression of CRF1 and CRF2 receptors in human cancers. J Clin Endocrinol Metab 88:3312-3320 (Pubitemid 36877510)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.7
, pp. 3312-3320
-
-
Reubi, J.C.1
Waser, B.2
Vale, W.3
Rivier, J.4
-
8
-
-
12244253775
-
A new role for corticotropin-releasing factor receptor-2: Suppression of vascularization
-
DOI 10.1016/S1050-1738(02)00214-1, PII S1050173802002141
-
Bale TL, Giordano FJ, Vale WW (2003) A new role for corticotrophin- releasing factor receptor-2: suppression of vascularization. Trends Cardiovasc Med 13:68-71 (Pubitemid 36175530)
-
(2003)
Trends in Cardiovascular Medicine
, vol.13
, Issue.2
, pp. 68-71
-
-
Bale, T.L.1
Giordano, F.J.2
Vale, W.W.3
-
9
-
-
42649105799
-
Urocortin's inhibition of tumor growth and angiogenesis in hepatocellular carcinoma via corticotrophin-releasing factor receptor 2
-
DOI 10.1080/07357900701788106, PII 792701860
-
Wang J, Xu Y, Xu Y, Zhu H, Zhang R, Zhang G, Li S (2008) Urocortin's inhibition of tumor growth and angiogenesis in hepatocellular carcinoma via corticotrophin-releasing factor receptor 2. Cancer Invest 26:359-368 (Pubitemid 351601386)
-
(2008)
Cancer Investigation
, vol.26
, Issue.4
, pp. 359-368
-
-
Wang, J.1
Xu, Y.2
Xu, Y.3
Zhu, H.4
Zhang, R.5
Zhang, G.6
Li, S.7
-
10
-
-
0029739615
-
A model of angiogenesis in the mouse cornea
-
Kenyon BM, Voest EE, Chen CC, Flynn E, Folkman J, D'Amato RJ (1996) A model of angiogenesis in the mouse cornea. Invest Ophtalmol Vis Sci 37:1625-1632 (Pubitemid 26271414)
-
(1996)
Investigative Ophthalmology and Visual Science
, vol.37
, Issue.8
, pp. 1625-1632
-
-
Kenyon, B.M.1
Voest, E.E.2
Chen, C.C.3
Flynn, E.4
Folkman, J.5
D'Amato, R.J.6
-
11
-
-
77958516149
-
A placebo-controlled study investigating the dexamethasone-sparing effects of corticorelin acetate in patients with primary or metastatic brain tumors and peritumoral edema
-
abstr 2078
-
Recht LD, Mechtler L, Phuphanich S, Hormigo A, Hines V, Milsted R, O'Connor PC, Ryan RP, Wong ET (2009) A placebo-controlled study investigating the dexamethasone-sparing effects of corticorelin acetate in patients with primary or metastatic brain tumors and peritumoral edema. J Clin Oncol 27:abstr 2078
-
(2009)
J Clin Oncol
, vol.27
-
-
Recht, L.D.1
Mechtler, L.2
Phuphanich, S.3
Hormigo, A.4
Hines, V.5
Milsted, R.6
O'Connor, P.C.7
Ryan, R.P.8
Wong, E.T.9
-
12
-
-
78751472524
-
A long-term openlabel extension study examining the steroid-sparing effects of corticorelin acetate in patients with cerebral tumors
-
abstr 2079
-
Mechtler L, Wong ET, Hormigo A, Pannullo S, Hines V, Milsted R, O'Connor PO, Ryan RP, Recht L (2009) A long-term openlabel extension study examining the steroid-sparing effects of corticorelin acetate in patients with cerebral tumors. J Clin Oncol 27:abstr 2079
-
(2009)
J Clin Oncol
, vol.27
-
-
Mechtler, L.1
Wong, E.T.2
Hormigo, A.3
Pannullo, S.4
Hines, V.5
Milsted, R.6
O'Connor, P.O.7
Ryan, R.P.8
Recht, L.9
-
13
-
-
76749171098
-
A randomized, double-blind study comparing corticorelin acetate with dexamethasone in patients with primary malignant glioma who require increased dexamethasone doses to control symptoms of peritumoral brain edema
-
abstr 2080
-
Shapiro WR, Mechtler L, Cher L, Wheeler H, Hines V, Milsted R, O'Connor PC, Ryan RP, L. Recht L (2009) A randomized, double-blind study comparing corticorelin acetate with dexamethasone in patients with primary malignant glioma who require increased dexamethasone doses to control symptoms of peritumoral brain edema. J Clin Oncol 27:abstr 2080
-
(2009)
J Clin Oncol
, vol.27
-
-
Shapiro, W.R.1
Mechtler, L.2
Cher, L.3
Wheeler, H.4
Hines, V.5
Milsted, R.6
O'Connor, P.C.7
Ryan, R.P.8
L Recht, L.9
-
14
-
-
68849124489
-
Corticorelin acetate injections for the treatment of peritumoral brain edema
-
Moliterno JA, Henry E, Pannullo SC (2009) Corticorelin acetate injections for the treatment of peritumoral brain edema. Expert Opin Investig Drugs 18:1413-1419
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1413-1419
-
-
Moliterno, J.A.1
Henry, E.2
Pannullo, S.C.3
-
15
-
-
78751543902
-
Corticorelin acetate exhibits preclinical antitumor activity against the human glioma U87 xenograft
-
abstr 2326
-
Ryan R, Moroz M, Berestein T, Evans-Freke S, Gamez I, Hines V, and Blasberg R (2009) Corticorelin acetate exhibits preclinical antitumor activity against the human glioma U87 xenograft. Proc Am Assoc Cancer Res, abstr 2326
-
(2009)
Proc Am Assoc Cancer Res
-
-
Ryan, R.1
Moroz, M.2
Berestein, T.3
Evans-Freke, S.4
Gamez, I.5
Hines, V.6
Blasberg, R.7
-
16
-
-
79952937440
-
Corticorelin acetate exhibits preclinical antitumor activity, alone and with bevacizumab, against human brain tumor models
-
abstr 1557
-
Gamez I, Ryan R, and Keir S (2010) Corticorelin acetate exhibits preclinical antitumor activity, alone and with bevacizumab, against human brain tumor models. Proc Am Assoc Cancer Res, abstr 1557
-
(2010)
Proc Am Assoc Cancer Res
-
-
Gamez, I.1
Ryan, R.2
Keir, S.3
-
17
-
-
70349277438
-
Monoclonal antibodies targeting vascular endothelial growth factor: Current status and future challenges in cancer therapy
-
Hsu JY, Wakelee HA (2009) Monoclonal antibodies targeting vascular endothelial growth factor: current status and future challenges in cancer therapy. BioDrugs 23(5):289-304
-
(2009)
BioDrugs
, vol.23
, Issue.5
, pp. 289-304
-
-
Hsu, J.Y.1
Wakelee, H.A.2
-
19
-
-
0004252445
-
-
4th edn. Prentice-Hall, Upper Saddle River
-
Zar JH (1999) Biostatistical analysis, 4th edn. Prentice-Hall, Upper Saddle River
-
(1999)
Biostatistical Analysis
-
-
Zar, J.H.1
-
20
-
-
34547765468
-
Antitumor activity of capecitabine and bevacizumab combination in a human estrogen receptor-negative breast adenocarcinoma xenograft model
-
Higgins B, Kolinsky K, Linn M, Adames V, Zhang YE, Moisa C, Dugan U, Heimbrook D, Packman K (2007) Antitumor activity of capecitabine and bevacizumab combination in a human estrogen receptor-negative breast adenocarcinoma xenograft model. Anticancer Res 27:2279-2287 (Pubitemid 47228065)
-
(2007)
Anticancer Research
, vol.27
, Issue.4 B
, pp. 2279-2287
-
-
Higgins, B.1
Kolinsky, K.2
Linn, M.3
Adames, V.4
Zhang, Y.-E.5
Moisa, C.6
Dugan, U.7
Heimbrook, D.8
Packman, K.9
-
21
-
-
68349106656
-
Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models
-
Yanagisawa M, Fujimoto-Ouchi K, Yorozu K, Yamashita Y, Mori K (2009) Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models. Oncol Rep 22:241-247
-
(2009)
Oncol Rep
, vol.22
, pp. 241-247
-
-
Yanagisawa, M.1
Fujimoto-Ouchi, K.2
Yorozu, K.3
Yamashita, Y.4
Mori, K.5
-
22
-
-
13444278498
-
Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
-
Gerber HP, Ferrara N (2005) Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res 65:671-680
-
(2005)
Cancer Res
, vol.65
, pp. 671-680
-
-
Gerber, H.P.1
Ferrara, N.2
-
23
-
-
0028935608
-
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
-
Warren RS, Yuan H, Matli MR, Gillett NA, Ferrara N (1995) Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J Clin Invest 95:1789-1797
-
(1995)
J Clin Invest
, vol.95
, pp. 1789-1797
-
-
Warren, R.S.1
Yuan, H.2
Matli, M.R.3
Gillett, N.A.4
Ferrara, N.5
-
24
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
DOI 10.1038/362841a0
-
Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362:841-844 (Pubitemid 23132159)
-
(1993)
Nature
, vol.362
, Issue.6423
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
25
-
-
0033018871
-
Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans
-
Mordenti J, Thomsen K, Licko V, Chen H, Meng YG, Ferrara N (1999) Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans. Toxicol Pathol 27:14-21 (Pubitemid 29075738)
-
(1999)
Toxicologic Pathology
, vol.27
, Issue.1
, pp. 14-21
-
-
Mordenti, J.1
Thomsen, K.2
Licko, V.3
Chen, H.4
Meng, Y.G.5
Ferrara, N.6
-
26
-
-
47549084965
-
Inhibitory effect of bevacizumab on the angiogenesis and growth of retinoblastoma
-
DOI 10.1001/archopht.126.7.953
-
Lee SY, Kim DK, Cho JH, Koh JY, Yoon YH (2008) Inhibitory effect of bevacizumab on the angiogenesis and growth of retinoblastoma. Arch Ophthalmol 126:953-958 (Pubitemid 352008378)
-
(2008)
Archives of Ophthalmology
, vol.126
, Issue.7
, pp. 953-958
-
-
Lee, S.Y.1
Kim, D.-K.2
Cho, J.H.3
Koh, J.-Y.4
Yoon, Y.H.5
-
27
-
-
41649112581
-
Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation
-
DOI 10.1073/pnas.0712366105
-
Hao Z, Huang Y, Cleman J, Jovin IS, Vale WW, Bale TL, Giordano FJ (2008) Urocortin 2 inhibits tumor growth via effects on vascularization and cell proliferation. Proc Natl Acad Sci USA 105:3939-3944 (Pubitemid 351723503)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.10
, pp. 3939-3944
-
-
Hao, Z.1
Huang, Y.2
Cleman, J.3
Jovin, I.S.4
Vale, W.W.5
Bale, T.L.6
Giordano, F.J.7
-
28
-
-
13144283610
-
Anti-neoplastic properties of human corticotropin releasing factor: Involvement of the nitric oxide pathway
-
Tjuvajev J, Kolesnikov Y, Joshi R, Sherinski J, Koutcher L, Zhou Y, Matei C, Koutcher J, Kreek MJ, Blasberg R (1998) Antineoplastic properties of human corticotropin releasing factor: involvement of the nitric oxide pathway. In Vivo 12:1-10 (Pubitemid 28177273)
-
(1998)
In Vivo
, vol.12
, Issue.1
, pp. 1-10
-
-
Tjuvajev, J.1
Kolesnikov, Y.2
Joshi, R.3
Sherinski, J.4
Koutcher, L.5
Zhou, Y.6
Matei, C.7
Koutcher, J.8
Kreek, M.-J.9
Blasberg, R.10
-
29
-
-
79959623915
-
-
Investigator's Brochure Xerecept® (Corticorelin acetate): Version 1.0 Celtic Pharma Development Services Inc., New York
-
Investigator's Brochure Xerecept® (Corticorelin acetate): Version 1.0 Celtic Pharma Development Services Inc., New York
-
-
-
-
30
-
-
0021967251
-
Continuous administration of synthetic ovine corticotropin-releasing factor in man. Physiological and pathophysiological implications
-
Schulte HM, Chrousos GP, Gold PW, Booth JD, Oldfield EH, Cutler GB Jr, Loriaux DL (1985) Continuous administration of synthetic ovine corticotropin-releasing factor in man. Physiological and pathophysiological implications. J Clin Invest 75:1781-1785 (Pubitemid 15237785)
-
(1985)
Journal of Clinical Investigation
, vol.75
, Issue.6
, pp. 1781-1785
-
-
Schulte, H.M.1
Chrousos, G.P.2
Gold, P.W.3
|